Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Simona Riva"'
Autor:
Luca Barbero, Hugues Dolgos, Dieter Gallemann, Simona Riva, Mirza Bojić, F. Peter Guengerich, Achim Freisleben
Publikováno v:
Drug Metabolism and Disposition. 42:1438-1446
Cilengitide is a stable cyclic pentapeptide containing an Arg-Gly-Asp motif responsible for selective binding to αVβ3 and αVβ5 integrins. The candidate drug showed unexpected inhibition of cytochrome P450 (P450) 3A4 at high concentrations, that i
Autor:
Stefano Donadio, Simona Riva, Gianpaolo Candiani, Gabriella Romano, Daniela Jabes, Cristina Brunati
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:1671-1676
NAI-107 is a novel lantibiotic active against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), glycopeptide-intermediate S. aureus (GISA), and vancomycin-resistant enterococci (VRE). The aim of this study was to e
Autor:
Clarissa Porzio Vernino, Rita Mastroianni, Simona Riva, Barbara Marsiglia, Luca Barbero, Marina Feroggio
Publikováno v:
Journal of Analytical & Bioanalytical Techniques. 6
Evaluation of the in-vivo concentration of monoclonal antibody (mAb) mixtures is a challenging task. Here we report the application of an LC-MS bioanalytical method to quantify in monkey serum the Sym004, an equimolar mixture of two monoclonal antibo
Autor:
Luigi Colombo, Simona Riva, Marco Cavaleri, James A. Dowell, Martin Stogniew, Marco Guanci, Anna Valagussa
Publikováno v:
Journal of Antimicrobial Chemotherapy. 55:ii31-ii35
Objectives: The pharmacokinetics, tissue distribution and excretion routes of dalbavancin, a semi-synthetic glycopeptide, were investigated in rats. Methods: A 20 mg/kg intravenous dose of dalbavancin or [ 3 H]dalbavancin was administered to rats in
Autor:
Simona Riva, Gabriella Romano, Daniela Jabes, Cristina Brunati, Gianpaolo Candiani, Marco Cavaleri
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:1118-1123
Infections due to methicillin-resistant Staphylococcus aureus (MRSA) are an important cause of morbidity and mortality in hospital patients. Moreover, increased incidences of outpatient MRSA have been recently reported. This study investigated the ba
Autor:
Matteo Simone, Sonia I. Maffioli, Gabriella Romano, Gianpaolo Candiani, Cristina Brunati, Rosaria Rossi, Simona Riva, Daniela Jabes, Eleonora Gaspari, Stefano Donadio
Publikováno v:
Antimicrobial agents and chemotherapy. 58(4)
NAI-603 is a ramoplanin derivative designed to overcome the tolerability issues of the parent drug as a systemic agent. NAI-603 is highly active against aerobic and anaerobic Gram-positive bacteria, with MICs ranging from 0.008 to 8 μg/ml. MICs were
Autor:
Simona Riva, Stefano Donadio, Eleonora Gaspari, Rosaria Rossi, Cristina Brunati, Daniela Jabes, Matteo Simone, Gabriella Romano, Gianpaolo Candiani, Sonia I. Maffioli
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:6675-6675
Autor:
Mandy Agresta, Simona Riva, Giuseppe Pedrocchi-Fantoni, Daniele Losi, Ezio Fasoli, Paola D'Arrigo, Stefano Servi, Davide Tessaro
Alkylphosphocholines (APC) with one or more methylene groups in the alkyl chain replaced by oxygen atoms or carbonyl groups, or both have been assembled modularly using omega-diols as central building blocks. Out of 25 new compounds of this kind, 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486c5530b0757113c9554a702bef20ca
http://hdl.handle.net/11311/557122
http://hdl.handle.net/11311/557122