Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Simona Plesselova"'
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Akademický článek
Poly(ethylene-imine)-Functionalized Magnetite Nanoparticles Derivatized with Folic Acid: Heating and Targeting Properties
Autor: Mariano Ortega-Muñoz, Simona Plesselova, Angel V. Delgado, Francisco Santoyo-Gonzalez, Rafael Salto-Gonzalez, Maria Dolores Giron-Gonzalez, Guillermo R. Iglesias, Francisco Javier López-Jaramillo
Publikováno v: Polymers, Vol 13, Iss 10, p 1599 (2021)
Magnetite nanoparticles (MNPs) coated by branched poly (ethylene-imine) (PEI) were synthesized in a one-pot. Three molecular weights of PEI were tested, namely, 1.8 kDa (sample MNP-1), 10 kDa (sample MNP-2), and 25 kDa (sample MNP-3). The MNP-1 parti
Externí odkaz: https://doaj.org/article/29c26219ce474dd78cb05198575d1425
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2
Reduction of Metastasis via Epigenetic Modulation in a Murine Model of Metastatic Triple Negative Breast Cancer (TNBC)
Autor: Jessica L. S. Zylla, Mariah M. Hoffman, Simona Plesselova, Somshuvra Bhattacharya, Kristin Calar, Yohannes Afeworki, Pilar de la Puente, Etienne Z. Gnimpieba, W. Keith Miskimins, Shanta M. Messerli
Publikováno v: Cancers; Volume 14; Issue 7; Pages: 1753
This study investigates the effects of a dual selective Class I histone deacetylase (HDAC)/lysine-specific histone demethylase 1A (LSD1) inhibitor known as 4SC-202 (Domatinostat) on tumor growth and metastasis in a highly metastatic murine model of T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f40f65ffdf1daeab566f21480d0e545
https://pubmed.ncbi.nlm.nih.gov/35406526
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3
Amphiphilic-like carbon dots as antitumoral drug vehicles and phototherapeutical agents
Autor: Simona Plesselova, M. Dolores Giron-Gonzalez, Fernando Hernandez-Mateo, F. Javier Lopez-Jaramillo, Ángel V. Delgado, Rafael Salto-Gonzalez, Francisco Santoyo-Gonzalez, Guillermo R. Iglesias, Mariano Ortega-Muñoz, Paula Vargas-Navarro
Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
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The work was financially supported by the Spanish institutions Ministerio de Ciencia, Innovacion y Universidades (PGC2018-098770-B-I00 and CTQ2017-86125-P) and Junta de Andalucia (ProgramaOperativo FEDER 2014-2020, grants B-FQM-141-UGR18, A1-FQM-341-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d24b3841b6d47d1eff026ab0200e96
http://hdl.handle.net/10481/71260
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4
Polyethylenimine-Bisphosphonate-Cyclodextrin Ternary Conjugates: Supramolecular Systems for the Delivery of Antineoplastic Drugs
Autor: Francisco J Reche-Perez, Maria Dolores Giron-Gonzalez, Fernando Hernandez-Mateo, Francisco Santoyo-Gonzalez, Simona Plesselova, Pablo Garcia-Cerezo, Víctor Blanco, Rafael Salto-Gonzalez
Publikováno v: Journal of Medicinal Chemistry
Bisphosphonates (BPs) are bone-binding molecules that provide targeting capabilities to bone cancer cells when conjugated with drug-carrying polymers. This work reports the design, synthesis, and biological evaluation of polyethyleneimine− BP−cyc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cbee3535dc6eff6991e5ef422ff261
https://hdl.handle.net/10481/80467
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5
Single chain variable fragment fused to maltose binding protein: a modular nanocarrier platform for the targeted delivery of antitumorals
Autor: Rafael Salto-Gonzalez, Francisco J Reche-Perez, Simona Plesselova, Maria Dolores Giron-Gonzalez, Eduardo De Los Reyes-Berbel, Mariano Ortega-Muñoz, Fernando Hernandez-Mateo, Francisco Javier Lopez-Jaramillo, Francisco Santoyo-Gonzalez
Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
This work was supported by grants CTQ2014-55474-C2-1-R, CTQ2014-55474-C2-2-R and CTQ2017-86125-P from the Ministerio Economia, Industria y Competitividad (co-financed by FEDER funds). SP is supported by a FPU fellowship (FPU17/ 04749). We acknowledge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319a2c263007a8a2a4be3429f738ffbb
https://pubmed.ncbi.nlm.nih.gov/33432316
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6
Poly(ethylene-imine)-Functionalized Magnetite Nanoparticles Derivatized with Folic Acid: Heating and Targeting Properties
Autor: Rafael Salto-Gonzalez, Simona Plesselova, Francisco Javier Lopez-Jaramillo, Guillermo R. Iglesias, Maria Dolores Giron-Gonzalez, Ángel V. Delgado, Mariano Ortega-Muñoz, Francisco Santoyo-Gonzalez
Publikováno v: Polymers, Vol 13, Iss 1599, p 1599 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Polymers
Volume 13
Issue 10
Magnetite nanoparticles (MNPs) coated by branched poly (ethylene-imine) (PEI) were synthesized in a one-pot. Three molecular weights of PEI were tested, namely, 1.8 kDa (sample MNP-1), 10 kDa (sample MNP-2), and 25 kDa (sample MNP-3). The MNP-1 parti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15cc8f5f45e3c0e3e3ee5be2fe28d26
http://hdl.handle.net/10481/68553
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7
Quinolimide-based peptide biosensor for probing p25 in vitro and in living cells
Autor: Simona Plesselova, Angel Orte, Juan A. González-Vera, May C. Morris, Jose M. Paredes, Francisco Fueyo-González, Rafael Salto, Rosario Herranz, María D. Girón
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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CDK5 kinase is activated through interactions with different partners including the p35/p25 regulators. Active CDK5 plays a key role in several neuronal functions and its hyperactivity contributes to a variety of neurodegenerative processes and sever
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c413d9f84e27a8b6102c65aa741e95ba
http://hdl.handle.net/10261/238820
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8
Human Plasma-Derived 3D Cultures Model Breast Cancer Treatment Responses and Predict Clinically Effective Drug Treatment Concentrations
Autor: Pilar de la Puente, Simona Plesselova, Kristin Calar, Megan Jorgensen, Somshuvra Bhattacharya
Publikováno v: Cancers
Cancers, Vol 12, Iss 1722, p 1722 (2020)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Volume 12
Issue 7
Lack of efficacy and a low overall success rate of phase I-II clinical trials are the most common failures when it comes to advancing cancer treatment. Current drug sensitivity screenings present several challenges including differences in cell growt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf276d2fd9b82da6a34c9d67eba6c37
https://pubmed.ncbi.nlm.nih.gov/32610529
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9
Abstract A22: Feasibility and efficacy of a human-derived plasma 3D culture (huP3D) model to predict clinically effective drug treatment concentrations
Autor: Somshuvra Bhattacharya, Simona Plesselova, Pilar de la Puente, Kristin Calar
Publikováno v: Cancer Research. 80:A22-A22
Despite significant improvements in research and development in the cancer field, about 95% of oncology drugs in clinical trials fail to receive FDA approval. Compelling evidence suggests that three-dimensional (3D) cell culture techniques provide us
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c091f5f2a7febf1d94501a160fae7af
https://doi.org/10.1158/1538-7445.camodels2020-a22
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