Výsledky vyhledávání - "Simona Pellegrino"

Akademický článek

Main Disorders of Gastrointestinal Tract in Older People: An Overview

Autor: Antonella Gallo, Simona Pellegrino, Erika Pero, Maria Chiara Agnitelli, Caterina Parlangeli, Francesco Landi, Massimo Montalto

Publikováno v: Gastrointestinal Disorders, Vol 6, Iss 1, Pp 313-336 (2024)

From a physiological standpoint, aging is a progressive reduction in each organ system’s capacity to maintain homeostasis in the face of illness or stressors. With advancing age, gastrointestinal (GI) symptoms and signs may increase, not only due t

Externí odkaz: https://doaj.org/article/6666e5395e034401a6db460bc4e1afe0

Zobrazit plný text záznamu

Akademický článek

Real-Life Effectiveness of Mepolizumab on Forced Expiratory Flow between 25% and 75% of Forced Vital Capacity in Patients with Severe Eosinophilic Asthma

Autor: Angelantonio Maglio, Carolina Vitale, Simona Pellegrino, Cecilia Calabrese, Maria D’Amato, Antonio Molino, Corrado Pelaia, Massimo Triggiani, Girolamo Pelaia, Cristiana Stellato, Alessandro Vatrella

Publikováno v: Biomedicines, Vol 9, Iss 11, p 1550 (2021)

Severe eosinophilic asthma (SEA) is associated with high peripheral blood and airway eosinophilia, recurrent disease exacerbations and severe airflow limitation. Eosinophilic inflammation is also responsible for small airway disease (SAD) development

Externí odkaz: https://doaj.org/article/75cb49082e334b6f9ca52940d0d6f952

Zobrazit plný text záznamu

How can Biology of Aging Explain the Severity of COVID-19 in Older Adults

Autor: Antonella Gallo, Erika Pero, Simona Pellegrino, Noemi Macerola, Celeste Ambra Murace, Francesca Ibba, Maria Chiara Agnitelli, Francesco Landi, Massimo Montalto

Publikováno v: Clinics in geriatric medicine. 38(3)

Aging has been identified as one of the most relevant risk factors for poor outcomes in COVID-19 infection. Since now, different mechanisms responsible for worse outcomes in the elderly have been proposed, which include the remodeling of immune syste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92022acf34a30d819d1e711b6ee2d731
https://pubmed.ncbi.nlm.nih.gov/35868666

Zobrazit plný text záznamu

Effectiveness of benralizumab in severe eosinophilic asthma: Distinct sub-phenotypes of response identified by cluster analysis

Background: Benralizumab is effective in severe eosinophilic asthma (SEA), but suboptimal responses are observed in some patients. Although several factors have been associated with benralizumab response, no cluster analysis has yet been undertaken t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1735e2213a547239e34d66116bfef264
http://hdl.handle.net/10447/541238

Zobrazit plný text záznamu

Therapeutic effects of benralizumab assessed in patients with severe eosinophilic asthma: Real-life evaluation correlated with allergic and non-allergic phenotype expression

Autor: Giovanna Elisiana Carpagnano, Nicola Scichilone, Luigi Macchia, Alida Benfante, Claudia Crimi, Simona Pellegrino, Santi Nolasco, Giuseppe Spadaro, Alessandro Vatrella, Giuseppe Valenti, Giulia Scioscia, Maria D'Amato, Maria Filomena Caiaffa, Corrado Pelaia, Cecilia Calabrese, Domenico Ciotta, Girolamo Pelaia, Nunzio Crimi

Publikováno v: Journal of Asthma and Allergy
Journal of Asthma and Allergy, Vol Volume 14, Pp 163-173 (2021)

Corrado Pelaia,1 Claudia Crimi,2 Alida Benfante,3 Maria Filomena Caiaffa,4 Cecilia Calabrese,5 Giovanna Elisiana Carpagnano,6 Domenico Ciotta Jnr,7 Maria D’Amato,8 Luigi Macchia,9 Santi Nolasco,2 Girolamo Pelaia,1 Simona Pellegrino,7 Nicola Scichil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9ecfd37e9ccb22fe44100c39068c03
http://hdl.handle.net/11591/458968

Zobrazit plný text záznamu

Small airways function: evaluation in a population of adult patients with severe asthma and potential use as a response biomarker for anti-IL5 therapy

Autor: Alessandro Vatrella, Simona Pellegrino, Carolina Vitale, Girolamo Pelaia, Massimo Triggiani, Roberta Parente, Corrado Pelaia, Cecilia Calabrese, Cristiana Stellato, Angelantonio Maglio

Publikováno v: Airway pharmacology and treatment.

Background: Asthma is a disease characterized by heterogeneity in clinical presentation and pathophysiological mechanisms. A novel element of new studies is the role of the involvement of the small airways function (SAF) in asthma severity and in res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::797d92ab436081095d24600a4f057aee
https://doi.org/10.1183/13993003.congress-2020.2265

Zobrazit plný text záznamu

Phenotyping severe asthma: a rationale for biologic therapy

Autor: Simona Pellegrino, Corrado Pelaia, Angelantonio Maglio, Carolina Vitale, Cristiana Stellato, Alessandro Vatrella, Girolamo Pelaia

Asthma is a complex disease with heterogeneity in etiology, triggers, clinical characteristics and different responses to pharmacological therapies. Patients with severe uncontrolled asthma constit...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405d5a92f611dcd9752b2afc346e43d1
http://hdl.handle.net/11386/4754156

Zobrazit plný text záznamu

Benralizumab Effectiveness in Severe Eosinophilic Asthma with and without Chronic Rhinosinusitis with Nasal Polyps: A Real-World Multicenter Study

Autor: Giuseppe Valenti, Giovanna Elisiana Carpagnano, Simona Pellegrino, Domenico Ciotta, Alida Benfante, Corrado Pelaia, Maria Filomena Caiaffa, Nunzio Crimi, Girolamo Pelaia, Santi Nolasco, Raffaele Campisi, Luigi Macchia, Claudia Crimi, Giuseppe Spadaro, Maria D'Amato, Nicola Scichilone, Cecilia Calabrese, Alessandro Vatrella, Giulia Scioscia

Publikováno v: The Journal of Allergy and Clinical Immunology: In Practice. 9:4371-4380.e4

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) affects around 60% of patients with severe eosinophilic asthma (SEA). Benralizumab was recently approved for SEA add-on treatment. Objective: To assess the real-world effectiveness of benr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f634945eb8e2f966143ce1867ddfe832
https://doi.org/10.1016/j.jaip.2021.08.004

Zobrazit plný text záznamu

Real-Life Effectiveness of Mepolizumab on Forced Expiratory Flow between 25% and 75% of Forced Vital Capacity in Patients with Severe Eosinophilic Asthma

Autor: Cristiana Stellato, Massimo Triggiani, Corrado Pelaia, Girolamo Pelaia, Cecilia Calabrese, Antonio Molino, Alessandro Vatrella, Maria D'Amato, Simona Pellegrino, Angelantonio Maglio, Carolina Vitale

Publikováno v: Biomedicines
Volume 9
Issue 11
Biomedicines, Vol 9, Iss 1550, p 1550 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6126d0176c583c73411b00d4aee94092
https://doi.org/10.3390/biomedicines9111550

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání