Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Simona Patange"'
Autor:
Simona Patange, David A. Ball, Yihan Wan, Tatiana S. Karpova, Michelle Girvan, David Levens, Daniel R. Larson
Publikováno v:
Cell Reports, Vol 38, Iss 4, Pp 110292- (2022)
Summary: The MYC oncogene has been studied for decades, yet there is still intense debate over how this transcription factor controls gene expression. Here, we seek to answer these questions with an in vivo readout of discrete events of gene expressi
Externí odkaz:
https://doaj.org/article/0148514683b44686af79c07ff4811f4c
Publikováno v:
Synth Biol (Oxf)
The presence and impact of variability in cells as the source material for genome engineering are important to consider for the design, execution and interpretation of outcomes of a genome-engineering process. Variability may be present at the genoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b0e7156535cf373be32cc99f7d3e4f
https://europepmc.org/articles/PMC10029982/
https://europepmc.org/articles/PMC10029982/
Autor:
Simona Patange, Samantha Maragh
Publikováno v:
Biochemistry.
Genome editing is a rapidly evolving biotechnology with the potential to transform many sectors of industry such as agriculture, biomanufacturing, and medicine. This technology is enabled by an ever-growing portfolio of biomolecular reagents that spa
Publikováno v:
Current Opinion in Systems Biology. 8:7-15
Gene expression varies across cells in a population or a tissue. This heterogeneity has come into sharp focus in recent years through developments in new imaging and sequencing technologies. However, our ability to measure variation has outpaced our
Publikováno v:
J Mol Biol
Regulation of transcription by RNA Polymerase II (RNAPII) is a rapidly evolving area of research. Technological developments in microscopy have revealed insight into the dynamics, structure, and localization of transcription components within single
Publikováno v:
Biophysical Journal. 116:306a-307a
Publikováno v:
Biophysical Journal. 112:210a-211a
We seek to determine how the MYC oncogene modulates gene transcription kinetics with single-molecule imaging techniques.Thirty-five years after the discovery of MYC and despite intensive research effort, there is still little understanding of how thi
Publikováno v:
Journal of Community & Applied Social Psychology. 22:63-74
The paper presents a psychoanalytically informed analysis of the concept of hip-hop identity through the lens of a four-year social action research and documentary film project, titled Moving to the Beat (M2B). The M2B project sought to document and
Autor:
Heba I. Diab, Rosa Puertollano, Li Lishu, Jose A. Martina, Simona Patange, Lim Jeong-A, Nina Raben
Publikováno v:
Science Signaling. 7
The discovery of a gene network regulating lysosomal biogenesis and its transcriptional regulator transcription factor EB (TFEB) revealed that cells monitor lysosomal function and respond to degradation requirements and environmental cues. We report
Publikováno v:
Biophysical Journal. 108:564a
Pathogenic Vibrio cholerae easily transitions between fresh water reservoirs and host intestines, having exceptional adaptation to abrupt osmotic changes. Mechanosensitive (MS) channels in the inner membrane act as tension-sensitive release valves, e