Liprin-α1 promotes cell spreading on the extracellular matrix by affecting the distribution of activated integrins

Autor: Veronica Astro, Claudia Asperti, Simona Paris, Ivan de Curtis, Antonio Totaro

Publikováno v: Journal of Cell Science. 122:3225-3232

Integrin activation is needed to link the extracellular matrix with the actin cytoskeleton during cell motility. Protrusion requires coordination of actin dynamics with focal-adhesion turnover. We report that the adaptor protein liprin-alpha1 is stab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d97cd0e5100d5c3f1679d0f623313d6
https://doi.org/10.1242/jcs.054155

Characterization of the endogenous GIT1–βPIX complex, and identification of its association to membranes

Autor: Angela Bachi, Sara Gualdoni, Ivan de Curtis, Simona Paris, Lorena Za, Angela Cattaneo, Oronza A. Botrugno

Publikováno v: European Journal of Cell Biology. 85:35-46

G protein-coupled receptor kinase interactors (GITs) are adaptor proteins with ADP-ribosylating factor--GTPase-activating protein (ARF-GAP) activity that form complexes with the p21-activated kinase-interacting exchange factor (PIX) guanine nucleotid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706c2ec5c004f45f6e70ae6b42e9b597
https://doi.org/10.1016/j.ejcb.2005.09.018

Leucine-zipper-mediated homo- and hetero-dimerization of GIT family p95-ARF GTPase-activating protein, PIX-, paxillin-interacting proteins 1 and 2

Autor: Ivan de Curtis, Simona Paris, Paolo Santambrogio, Renato Longhi

Publikováno v: Biochemical journal (Lond., 1984) 372 (2003): 391–398.
info:cnr-pdr/source/autori:Paris S., Longhi R., Santambrogio P., De Curtis I./titolo:Leucine-zipper-mediated homo and hetero-dimerization of GIT family p95-ARF GTPase-activating protein, PIX-, paxillin-interacting proteins 1 and 2/doi:/rivista:Biochemical journal (Lond., 1984)/anno:2003/pagina_da:391/pagina_a:398/intervallo_pagine:391–398/volume:372

ADP-ribosylation factor GTPase-activating proteins (ARFGAPs) of the G-protein-coupled receptor kinase interactor 1/p95 paxillin kinase linker/p95-ARFGAP Pak-interacting exchange factor paxillin-binding protein (APP)-1 family are multidomain proteins,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c39e4585ca45aa82a8ab0efd04e57b
https://doi.org/10.1042/bj20030047

Analysis of the subcellular distribution of avian p95-APP2, an ARF-GAP orthologous to mammalian paxillin kinase linker

Autor: Ivan de Curtis, Simona Paris, Barbara Sporchia, Lorena Za

Publikováno v: The International Journal of Biochemistry & Cell Biology. 34:826-837

We describe here the identification and characterization of avian p95-APP2, a multi-domain protein of a recently identified family of ADP-ribosylation factor (ARF)-GTPase-activating proteins (GAPs) including mammalian G protein-coupled receptor kinas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d88d9d4c2e0c8e39138b01af8bd9281
https://doi.org/10.1016/s1357-2725(02)00008-0

New Diagnostic and Prognostic Models for the Development of Alcoholic Cirrhosis Based on Genetic Predisposition and Alcohol History

Autor: Monica Mischitelli, Alessandra Spagnoli, Aurelio Abbatecola, Claudia Codazzo, Marta Giacomelli, Simona Parisse, Rosellina Margherita Mancina, Claudia Rotondo, Fabio Attilia, Stefano Ginanni Corradini, Flaminia Ferri

Publikováno v: Biomedicines, Vol 11, Iss 8, p 2132 (2023)

Liver cirrhosis development is a multifactorial process resulting from a combination of environmental and genetic factors. The aim of the study was to develop accurate non-invasive diagnostic and prognostic models for alcoholic cirrhosis. Consecutive

Externí odkaz: https://doaj.org/article/013d5f3c4bd146af809ddac3036d0627