Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Simona Manzella"'
Autor:
Erine Craey, Fabian Hulpia, Jeroen Spanoghe, Simona Manzella, Lars E. Larsen, Mathieu Sprengers, Dimitri De Bundel, Ilse Smolders, Evelien Carrette, Jean Delbeke, Kristl Vonck, Paul Boon, Serge Van Calenbergh, Wytse J. Wadman, Robrecht Raedt
Publikováno v:
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
We report the design, synthesis, and validation of the novel compound photocaged N6-cyclopentyladenosine (cCPA) to achieve precisely localized and timed release of the parent adenosine A1 receptor agonist CPA using 405 nm light. Gi protein-coupled A1
Autor:
Jeroen, Spanoghe, Lars E, Larsen, Erine, Craey, Simona, Manzella, Annelies, Van Dycke, Paul, Boon, Robrecht, Raedt
Publikováno v:
International Journal of Molecular Sciences
Adenosine acts as an endogenous anticonvulsant and seizure terminator in the brain. Many of its anticonvulsive effects are mediated through the activation of the adenosine A1 receptor, a G protein-coupled receptor with a wide array of targets. Activa