Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Simona Manzella"'
Autor:
Marijke Vergaelen, Simona Manzella, Kristl Vonck, Erine Craey, Jeroen Spanoghe, Mathieu Sprengers, Evelien Carrette, Wytse Jan Wadman, Jean Delbeke, Paul Boon, Lars Emil Larsen, Robrecht Raedt
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 660 (2024)
The intrahippocampal kainic acid (IHKA) mouse model is an extensively used in vivo model to investigate the pathophysiology of mesial temporal lobe epilepsy (mTLE) and to develop novel therapies for drug-resistant epilepsy. It is characterized by pro
Externí odkaz:
https://doaj.org/article/02afdd2faea84223b1ec2bc09f9cb2c9
Autor:
Erine Craey, Fabian Hulpia, Jeroen Spanoghe, Simona Manzella, Lars E. Larsen, Mathieu Sprengers, Dimitri De Bundel, Ilse Smolders, Evelien Carrette, Jean Delbeke, Kristl Vonck, Paul Boon, Serge Van Calenbergh, Wytse J. Wadman, Robrecht Raedt
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 8887 (2022)
We report the design, synthesis, and validation of the novel compound photocaged N6-cyclopentyladenosine (cCPA) to achieve precisely localized and timed release of the parent adenosine A1 receptor agonist CPA using 405 nm light. Gi protein-coupled A1
Externí odkaz:
https://doaj.org/article/ebe67bf7ff904601a50d9497aa46580a
Autor:
Jeroen Spanoghe, Lars E. Larsen, Erine Craey, Simona Manzella, Annelies Van Dycke, Paul Boon, Robrecht Raedt
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 320 (2020)
Adenosine acts as an endogenous anticonvulsant and seizure terminator in the brain. Many of its anticonvulsive effects are mediated through the activation of the adenosine A1 receptor, a G protein-coupled receptor with a wide array of targets. Activa
Externí odkaz:
https://doaj.org/article/8bc5fb6f48a54c24a1da7a72ceee6e4f
Autor:
Annelies Van Dycke, Jeroen Spanoghe, Lars Emil Larsen, Simona Manzella, Erine Craey, Robrecht Raedt, Paul Boon
Publikováno v:
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
International Journal of Molecular Sciences, Vol 22, Iss 320, p 320 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 320, p 320 (2021)
Adenosine acts as an endogenous anticonvulsant and seizure terminator in the brain. Many of its anticonvulsive effects are mediated through the activation of the adenosine A1 receptor, a G protein-coupled receptor with a wide array of targets. Activa