Mutation of Somatostatin Receptor Type 5 in an Acromegalic Patient Resistant to Somatostatin Analog Treatment

Autor: Simona Mantovani, Enza Giammona, Emilia Ballaré, Giovanni Faglia, Anna Spada, Andrea Lania, Marcello Filopanti, Sabrina Corbetta, Luca Persani, Maura Arosio, Paolo Beck-Peccoz

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 86:3809-3814

Introduction of somatostatin analogs has greatly contributed to improving the prognosis of acromegaly. Although the majority of patients are effectively treated by these agents, resistance occurs in a subset of patients. So far, resistance to somatos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70d19722f905c545870a2121bc4debf
https://doi.org/10.1210/jcem.86.8.7787

Constitutively Active Gsα Is Associated with an Increased Phosphodiesterase Activity in Human Growth Hormone-Secreting Adenomas1

Autor: Simona Mantovani, Andrea Lania, Anna Spada, Emilia Ballaré, Marco Losa, Luca Persani

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 83:1624-1628

Because phosphodiesterase (PDE) expression and activity are controlled by cAMP, we investigated whether activating mutations of Gs alpha gene that occur in human GH-secreting adenomas are associated with increased PDE activity. We studied 10 adenomas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::635c7a735c0641fdece40ecf5e8a8f21
https://doi.org/10.1210/jcem.83.5.4814

Contents, Vol. 47, 1997

Autor: P. Chanson, X. Jeunemaitre, M. Talbot, D. Simpson, Emmanuel Gautherot, Annick Martin, Maria Luisa Brandi, Jp. Aubert, Catharina Larsson, F. Mantero, Cx. Zhang, David Wynford-Thomas, Claude Jaffiol, M. Boggild, Simona Mantovani, A.M. Masini, Eric Clauser, A. Angeli, Véronique Alvaro, Cristina Missale, G. Gunz, B. Fournes, A. Enjalbert, Olov Nilsson, I. Morange-Ramos, Charis Eng, B. Conte-Devolx, A. Courseaux, Eric Rouvier, A. Murat, Lars-Ove Farnebo, Alessandra Finardi, Filip Farnebo, G. Cadiot, P. Niccoli, B. Allolio, C. Beldjord, Massimo Giovanelli, Colette Auzan, P. Jaquet, P. Gaudray, Corinne Prévostel, Chiara Fiorentini, A. Ali, M. Giovagnetti, Pascal Meyer, R. Monier, B. Maes, Marco Losa, M. Terzolo, V. Aubert, Xavier Bertagna, Sandra Sigala, J.F. Hewy, W. Farrell, G. Arnaldi, M. Klein, A. Calender, J. Leclère, Jérôme Bertherat, Frederic Lenne, G. Osella, Patricia René, J. Bicknell, Andrea Lania, N. Porchet, Pf. Plouin, C. Gicquel, M.C. Béné, A. Barlier, Lois M. Mulligan, A. Boneu, L. Caccavelli, B. Caillou, Anna Spada, P. Rochefort, G. Opocher, G. Faure, Jacques Barbel, S. Giraud, Deborah J. Marsh, F. Michiels, Johannes Järhult, P. Rodien, Jacob Lagercrantz, Bin Tean Teh, J. Feunteun, G. Weryha, Dominique Joubert, M. Reincke, I. Schuffenecker, J.B. Corcuff, L. Mercken, Kerstin Sandelin, C. Dumont, M. Schlumberger, Y. Le Bouc, E. Modigliani, Yves de Keyzer, V. Pascal-Vigneron, Emilia Ballaré, Günther Weber, A.S. Bates, R.N. Clayton, I. Pellegrini-Bouiller, PierFranco Spano, N. Barbot, Gm. Lenoir

Publikováno v: Hormone Research. 47:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d297928ac32ca3c3c7aadb06ed80a60c
https://doi.org/10.1159/000185453

Induction of B1 bradykinin receptors in the kindled brain

Autor: Brice Ongali, Michele Simonato, Anna Binaschi, Simona Mantovani, Manuela Mazzuferi, Donata Rodi, Réjean Couture

Publikováno v: Kindling 6 ISBN: 9780387243801

Knowledge of the cellular and molecular mechanisms underlying the various forms of epilepsy could drive the search for new drugs and lead to improved therapies. The proposal of J.H. Jackson, put forward more than a century ago, that seizures are caus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc04481b484446efde8093f9b8a588b
http://hdl.handle.net/11392/1191991

Kainate Seizures Increase Nociceptin/Orphanin FQ Release in the Rat Hippocampus and Thalamus: a Microdialysis Study

Autor: Manuela Mazzuferi, Giuseppe Lopetuso, Daniela Landuzzi, Michele Simonato, Patrizia Romualdi, Simona Mantovani, Manuela Di Benedetto, Liliana Carmona Aparicio, Anna Binaschi, Sanzio Candeletti

The neuropeptide nociceptin/orphanin FQ (N/OFQ) has been suggested to play a facilitatory role in kainate seizure expression. Furthermore, mRNA levels for the N/OFQ precursor are increased following kainate seizures, while its receptor (NOP) density

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbeb48787c3b8b3c5222633b8cdd6151
http://hdl.handle.net/11585/1065