Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Simona Luatti"'
Autor:
Marco Romano, Daria Sollazzo, Sara Trabanelli, Martina Barone, Nicola Polverelli, Margherita Perricone, Dorian Forte, Simona Luatti, Michele Cavo, Nicola Vianelli, Camilla Jandus, Francesca Palandri, Lucia Catani
Publikováno v:
OncoImmunology, Vol 6, Iss 10 (2017)
Myelofibrosis (MF) is a clonal neoplasia associated with chronic inflammation due to aberrant cytokine production. Mutations in Janus Kinase-2 (JAK2), calreticulin (CALR) and myeloproliferative leukemia protein (MPL) genes have been recently associat
Externí odkaz:
https://doaj.org/article/4ca308e34de64e01b33d44ac98889cb5
Autor:
Daria Sollazzo, Dorian Forte, Nicola Polverelli, Margherita Perricone, Marco Romano, Simona Luatti, Nicola Vianelli, Michele Cavo, Francesca Palandri, Lucia Catani
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Myelofibrosis (MF) is a clonal neoplasia of the hemopoietic stem/progenitor cells associated with genetic mutations in the Janus kinase 2 (JAK2), myeloproliferative leukemia virus oncogene (MPL), and calreticulin (CALR) genes. MF is also characterize
Externí odkaz:
https://doaj.org/article/be1152e0768143e3bb9d10edfc0b312f
Autor:
Elisa Leo, Manuela Mancini, Michela Aluigi, Simona Luatti, Fausto Castagnetti, Nicoletta Testoni, Simona Soverini, Maria Alessandra Santucci, Giovanni Martinelli
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81425 (2013)
Beta Catenin signaling is critical for the self-renewal of leukemic stem cells in chronic myeloid leukemia. It is driven by multiple events, enhancing beta catenin stability and promoting its transcriptional co-activating function. We investigated th
Externí odkaz:
https://doaj.org/article/9ef74c8aa53d474d90f5616c007b2a39
Autor:
Francesca Palandri, Fausto Castagnetti, Simona Soverini, Angela Poerio, Gabriele Gugliotta, Simona Luatti, Marilina Amabile, Giovanni Martinelli, Gianantonio Rosti, Michele Baccarani
Publikováno v:
Haematologica, Vol 94, Iss 12 (2009)
An increase in the serum concentration of pancreatic enzymes (amylase and lipase) was reported in a proportion of imatinib-resistant and/or intolerant Philadelphia-positive chronic myeloid leukemia patients treated with nilotinib. Acute pancreatitis
Externí odkaz:
https://doaj.org/article/58e31ef29a814c3e8e4eff775098810f
Autor:
Francesca Palandri, Fausto Castagnetti, Giuliana Alimena, Nicoletta Testoni, Massimo Breccia, Simona Luatti, Giovanna Rege-Cambrin, Fabio Stagno, Giorgina Specchia, Bruno Martino, Luciano Levato, Serena Merante, Anna Maria Liberati, Fabrizio Pane, Giuseppe Saglio, Daniele Alberti, Giovanni Martinelli, Michele Baccarani, Gianantonio Rosti
Publikováno v:
Haematologica, Vol 94, Iss 2 (2009)
Background Imatinib mesylate is the first line treatment for chronic myeloid leukemia. The advent of imatinib increased survival significantly in patients in an advanced phase of the disease. However, few long-term data on the outcome of these patien
Externí odkaz:
https://doaj.org/article/38a4fbd4de0d488ba9856689ae63c462
Autor:
Francesca Palandri, Fausto Castagnetti, Nicoletta Testoni, Simona Luatti, Giulia Marzocchi, Simona Bassi, Massimo Breccia, Giuliana Alimena, Ester Pungolino, Giovanna Rege-Cambrin, Riccardo Varaldo, Maurizio Miglino, Giorgina Specchia, Eliana Zuffa, Felicetto Ferrara, Monica Bocchia, Giuseppe Saglio, Fabrizio Pane, Daniele Alberti, Giovanni Martinelli, Michele Baccarani, Gianantonio Rosti
Publikováno v:
Haematologica, Vol 93, Iss 12 (2008)
Background Imatinib mesylate is the first line treatment for chronic myeloid leukemia. In patients with advanced phase of the disease, the advent of imatinib significantly increased survival. However, few long-term data, based on large, prospective a
Externí odkaz:
https://doaj.org/article/3f6cd0d8cc154c3abf09a722043029a1
Autor:
Simona Soverini, Sabrina Colarossi, Alessandra Gnani, Fausto Castagnetti, Gianantonio Rosti, Costanza Bosi, Stefania Paolini, Michela Rondoni, Pier Paolo Piccaluga, Francesca Palandri, Panagiota Giannoulia, Giulia Marzocchi, Simona Luatti, Nicoletta Testoni, Ilaria Iacobucci, Daniela Cilloni, Giuseppe Saglio, Michele Baccarani, Giovanni Martinelli
Publikováno v:
Haematologica, Vol 92, Iss 3 (2007)
The emergence of resistance to the Bcr-Abl inhibitor imatinib mesylate in patients with Philadelphia chromosome-positive (Ph+) leukemia has prompted the development of second-generation compounds active against several imatinib-insensitive mutant for
Externí odkaz:
https://doaj.org/article/8907d98d9e554c64b972ccf45d8f6f92
Autor:
Carmen Baldazzi, Simona Luatti, Giulia Marzocchi, Alessandra Grassi, Michele Cavo, Nicoletta Testoni
Publikováno v:
Cancer Genetics. :35-39
The translocation t(5;12)(q31;p13)/ETV6::ACSL6 is a rare cytogenetic abnormality, although it is reported in various myeloid malignancies. To date, only 16 cases of t(5;12) and ETV6::ACSL6 rearrangement, confirmed by either molecular or Fluorescence
Autor:
Giulia Marzocchi, Carmela Gurrieri, Elisa Zuffa, Gaia Ameli, Maria Antonella Bardi, Cristina Papayannidis, Rossella Paolini, Nicoletta Testoni, Giovanni Martinelli, Simona Luatti, Laura Bonaldi, Michele Cavo, Antonio Cuneo, Emanuela Ottaviani, Gian Matteo Rigolin, Carmen Baldazzi
Publikováno v:
Genes, Chromosomes and Cancer. 55:375-388
Chromosomal rearrangements involving 3q26 are recurrent findings in myeloid malignancies leading to MECOM overexpression, which has been associated with a very poor prognosis. Other 3q abnormalities have been reported and cryptic MECOM rearrangements
Autor:
Stefania Paolini, Gaia Ameli, Giulia Marzocchi, Nicoletta Testoni, Simona Luatti, Carmen Baldazzi, Michele Cavo, Cristina Papayannidis, Giovanni Martinelli
Publikováno v:
American Journal of Hematology. 91:E14-E16