Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Simona Lodato"'
Autor:
Camilla Fontana, Federica Marasca, Livia Provitera, Sara Mancinelli, Nicola Pesenti, Shruti Sinha, Sofia Passera, Sergio Abrignani, Fabio Mosca, Simona Lodato, Beatrice Bodega, Monica Fumagalli
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background Preterm birth affects almost 9–11% of newborns and is one of the leading causes of childhood neurodevelopmental disabilities; the underlying molecular networks are poorly defined. In neurons, retrotransposons LINE-1 (L1) are an
Externí odkaz:
https://doaj.org/article/eb9f42366ba641508cb079d17db5b002
Autor:
Martin Sauvageau, Loyal A Goff, Simona Lodato, Boyan Bonev, Abigail F Groff, Chiara Gerhardinger, Diana B Sanchez-Gomez, Ezgi Hacisuleyman, Eric Li, Matthew Spence, Stephen C Liapis, William Mallard, Michael Morse, Mavis R Swerdel, Michael F D’Ecclessis, Jennifer C Moore, Venus Lai, Guochun Gong, George D Yancopoulos, David Frendewey, Manolis Kellis, Ronald P Hart, David M Valenzuela, Paola Arlotta, John L Rinn
Publikováno v:
eLife, Vol 2 (2013)
Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few have been tested for in vivo relevance through genetic ablation in animal models. To investigate the functional relevance of lncRNAs in various physiological cond
Externí odkaz:
https://doaj.org/article/5fdb35f4c02f45c69bc508db25a26cb3
Autor:
Federica Rizzo, Silvia Bono, Marc David Ruepp, Sabrina Salani, Linda Ottoboni, Elena Abati, Valentina Melzi, Chiara Cordiglieri, Serena Pagliarani, Roberta De Gioia, Alessia Anastasia, Michela Taiana, Manuela Garbellini, Simona Lodato, Paolo Kunderfranco, Daniele Cazzato, Daniele Cartelli, Caterina Lonati, Nereo Bresolin, Giacomo Comi, Monica Nizzardo, S Corti
Mitofusin-2 (MFN2) is an outer mitochondrial membrane protein essential for mitochondrial networking in most cells. Autosomal dominant mutations in the MFN2 gene cause Charcot-Marie-Tooth type 2A disease (CMT2A), a severe and disabling sensory-motor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce717771b8aeb8132018f9768aa5df20
https://doi.org/10.21203/rs.3.rs-2817290/v1
https://doi.org/10.21203/rs.3.rs-2817290/v1
Autor:
Alessandro M Mozzarelli, Alice Bertocchi, Sara Mancinelli, Sara Carloni, Daniele Braga, Michela Matteoli, Martina Bellini, Giuseppe Penna, Simona Lodato, Marco Erreni, Daria Manganaro, Daniel Fernandez Perez, Silvia Giugliano, Antonella Borreca, Maria Rescigno, Federico Colombo, Diego Pasini, Antonio Di Sabatino
Publikováno v:
Science (New York, N.Y.). 374(6566)
Up to 40% of patients with inflammatory bowel disease present with psychosocial disturbances. We previously identified a gut vascular barrier that controls the dissemination of bacteria from the intestine to the liver. Here, we describe a vascular ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd354f8d001ecb5b7ed56b037f295bc
https://pubmed.ncbi.nlm.nih.gov/34782782
https://pubmed.ncbi.nlm.nih.gov/34782782
Autor:
Sara Mancinelli, Simona Lodato
Publikováno v:
Current Opinion in Neurobiology. 53:146-155
The neocortex is by far one of the most complex regions of the mammalian brain, characterized by an extraordinary diversity of neuronal and non-neuronal cell types, whose coordinated development and function guarantee the execution of high-order cogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a06c3952b07b0658aecf106306db7e
https://doi.org/10.1016/j.conb.2018.08.001
https://doi.org/10.1016/j.conb.2018.08.001
Autor:
Wen Yuan, Sai Ma, Juliana R. Brown, Kwanho Kim, Vanessa Murek, Lucia Trastulla, Alexander Meissner, Simona Lodato, Ashwin S. Shetty, Joshua Z. Levin, Jason D. Buenrostro, Michael J. Ziller, Paola Arlotta
Publikováno v:
Nature Neuroscience
Mammalian neocortical neurons span one of the most diverse cell type spectra of any tissue. Cortical neurons are born during embryonic development, and their maturation extends into postnatal life. The regulatory strategies underlying progressive neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3948dd902f9b2890181f8d1773583b84
https://pubmed.ncbi.nlm.nih.gov/35915179
https://pubmed.ncbi.nlm.nih.gov/35915179
Autor:
Paola Arlotta, Ashwin S. Shetty, Xin Jin, Lan Nguyen, Amy X. Guo, Simona Lodato, Elise B. Robinson, Sean Simmons, Paul Oyler, Joshua Z. Levin, Giulio Deangeli, Michelle Ko, Feng Zhang, Vahbiz Jokhi, Nathan C. Curry, Aviv Regev
Publikováno v:
PMC
An in vivo analysis of autism risk genes CRISPR targeting in vivo, especially in mammals, can be difficult and time consuming when attempting to determine the effects of a single gene. However, such studies may be required to identify pathological ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05decc1fc51450705164a7f5ea2ca306
https://doi.org/10.1126/science.aaz6063
https://doi.org/10.1126/science.aaz6063
Autor:
Marija Markicevic, Paolo Kunderfranco, Alberto Termanini, Davide Pozzi, Filippo Mirabella, Marco Rasile, Clara Akofa Amegandjin, Simona Lodato, Clelia Peano, Michela Matteoli, Genni Desiato, Valerio Zerbi, Giuliana Fossati, Elisabetta Menna, Christina Grimm, Sara Mancinelli, Raffaella Morini, Graziella Di Cristo
SummaryEarly prenatal inflammatory conditions are thought to represent a risk factor for different neurodevelopmental disorders, with long-term consequences on adult brain connectivity. Here we show that a transient IL-6 elevation, occurring at vulne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd141f83c545acf5b81f8742f8445c5
https://doi.org/10.1101/2020.11.02.364356
https://doi.org/10.1101/2020.11.02.364356
Autor:
Alexander Meissner, Kwanho Kim, Paola Arlotta, Ashwin S. Shetty, Michael J. Ziller, Lucia Trastulla, Jason D. Buenrostro, Wen Yuan, Juliana Brown, Joshua Z. Levin, Sai Ma, Vanessa Murek, Simona Lodato
Mammalian neocortical neurons span one of the most diverse cell type spectra of any tissue. The regulatory strategies that neurons use during progressive development and maturation remain unclear. We present an integrated single-cell epigenomic and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::066ff116b4e16971811e44c04b58fca8
https://doi.org/10.1101/2020.08.23.263434
https://doi.org/10.1101/2020.08.23.263434
Brain organoids: Human 3D models to investigate neuronal circuits assembly, function and dysfunction
Autor:
M. Tambalo, Simona Lodato
Publikováno v:
Brain research. 1746
The human brain is characterized by an extraordinary complexity of neuronal and nonneuronal cell types, wired together into patterned neuronal circuits, which represent the anatomical substrates for the execution of high-order cognitive functions. Br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9456cfb58ed62bc137fd05e9a80904
https://pubmed.ncbi.nlm.nih.gov/32717276
https://pubmed.ncbi.nlm.nih.gov/32717276