Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Simona Jevsevar"'
Autor:
Menci Kunstelj, Simona Jevsevar
Publikováno v:
Therapeutic Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8cea2e9e05e1135594e23ca6a78ee2
https://doi.org/10.1002/9783527644827.ch3
https://doi.org/10.1002/9783527644827.ch3
Publikováno v:
Biotechnology Journal. 5:113-128
Since the first PEGylated product was approved by the Food and Drug Administration in 1990, PEGylation has been widely used as a post-production modification methodology for improving biomedical efficacy and physicochemical properties of therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3454054e02535bb35a59d011198c2c
https://doi.org/10.1002/biot.200900218
https://doi.org/10.1002/biot.200900218
Autor:
Menci Kunstelj, Simon Caserman, Simona Jevsevar, Tanja Milunović, Mateja Kusterle, Vladka Gaberc Porekar, Mark Schiefermeier
Publikováno v:
Analytical Biochemistry. 389:27-31
Pegylation is the most widely used and accepted methodology for half-life extension of biopharmaceutical drugs that also improves physicochemical and biological characteristics of proteins considerably. Most of the positive pharmacological effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d874491cdd6470c0d78d217e404f5b
https://doi.org/10.1016/j.ab.2009.03.023
https://doi.org/10.1016/j.ab.2009.03.023
Autor:
Simona Jevsevar, Jože Grdadolnik, Barbara Podobnik, Vladka Gaberc-Porekar, Irena Fonda, Viktor Menart
Publikováno v:
Biotechnology Progress. 21:632-639
Human granulocyte-colony stimulating factor (hG-CSF), an important biopharmaceutical drug used in oncology, is currently produced mainly in Escherichia coli. Expression of human hG-CSF gene in E. coli is very low, and therefore a semisynthetic, codon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c60e44de60915ff193117ac346c9e2c
https://doi.org/10.1021/bp0497839
https://doi.org/10.1021/bp0497839
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799303
Antibody fragments (Fab's) represent important structure for creating new therapeutics. Compared to full antibodies Fab' fragments possess certain advantages, including higher mobility and tissue penetration, ability to bind antigen monovalently and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2231c0cc194693d434fa7cfe24c35198
https://doi.org/10.1007/978-1-61779-931-0_15
https://doi.org/10.1007/978-1-61779-931-0_15
