Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Simona Giovagnetti"'
Autor:
Simona Giovagnetti, Roberta Galeazzi, Liana Spazzafumo, Raffaele Di Pillo, Sara Cecchini, Fabiola Olivieri, Gelsomina Malatesta, Alberto Montesanto, Roberto Antonicelli, Giuseppina Rose
Publikováno v:
Drugs & Aging
Objective The clinical efficacy of clopidogrel in secondary prevention of vascular events is hampered by marked inter-patient variability in drug response, which partially depends on genetic make-up. The aim of this pilot prospective study was to eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9199c8955f1cab2ed7ae6cd21084fb
http://europepmc.org/articles/PMC6061429
http://europepmc.org/articles/PMC6061429
Autor:
Elisa Righi, Rosaria Gesuita, Federica Alessandrini, Mauro Pesaresi, Francesco Brandimarti, Raffaele Giorgetti, Adriano Tagliabracci, Simona Giovagnetti, Roberta Galeazzi, Letizia De Angelis, Chiara Catalani
Publikováno v:
International Journal of Legal Medicine. 131:447-458
Venous thromboembolism (VTE) is a multifactorial disease determined by a combination of inherited and acquired factors. Inherited factors include mutations in the genes coding for coagulation factors, some of which seem to exert a differential influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d2c2ce8b3e91fcf17658cb867eb695
https://doi.org/10.1007/s00414-016-1508-z
https://doi.org/10.1007/s00414-016-1508-z
Autor:
Francesca Marchegiani, Simona Giovagnetti, Roberta Galeazzi, Mauro Provinciali, Elisa Pierpaoli, Fausto Moroni, Francesco Piacenza, Maurizio Cardelli, Stefania Appolloni
Publikováno v:
Thrombosis research. 156
Oral anticoagulation therapy (OAT) with coumarins (vitamin K antagonist) is the most used against thromboembolism. Prothrombin time (PT) International Normalized Ratio (INR) monitoring is fundamental to establish coumarins dosage and prevent bleeding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67681b95077652c33cfbcfe3f2ad416
https://pubmed.ncbi.nlm.nih.gov/28586696
https://pubmed.ncbi.nlm.nih.gov/28586696
Autor:
Liana Spazzafumo, Fabiola Olivieri, Roberto Antonicelli, Simona Giovagnetti, Claudio Franceschi, Roberta Galeazzi, Francesca Marchegiani, Maurizio Cardelli, C. Sirolla, Eugenio Mocchegiani
Publikováno v:
Mechanisms of Ageing and Development. 129:231-237
The elderly subjects affected by Acute Myocardial Infarction (AMI) have the highest risk of mortality. Our study was designed to improve the capability of mortality risk stratification in elderly AMI patients through the concurrent evaluations of dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c09d59f4d9ea1c0f64e9755931f88d
https://doi.org/10.1016/j.mad.2008.01.002
https://doi.org/10.1016/j.mad.2008.01.002
Autor:
Elena Mugianesi, Rosamaria Lisa, Raffaella Moresi, Luca Cavallone, Simona Giovagnetti, Claudio Franceschi, Maurizio Cardelli, Fabiola Olivieri, Francesca Marchegiani
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
The uneven distribution of Alu repetitive elements in the human genome is related to specific functional properties of genomic regions. We report the identification of a locus associated with human longevity in one of the chromosomal regions with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3695ee1830846b2a5cf4117b96c3160e
https://doi.org/10.1093/gerona/61.6.547
https://doi.org/10.1093/gerona/61.6.547
Autor:
Giuseppina Carrieri, Francesca Marchegiani, Fabiola Olivieri, Cinzia Molendini, Rosalia Stecconi, Chiara Trapassi, Giovanna De Benedictis, Dimitri Kletsas, Erika Marzi, Maurizio Cardelli, Luca Cavallone, Simona Giovagnetti, Claudio Franceschi
Publikováno v:
Aging Cell. 3:443-448
Sequence variations in a variety of pro- or anti-inflammatory cytokine genes have been found to influence successful aging and longevity. Because of the role played by the transforming growth factor beta1 (TGF-beta1) cytokine in inflammation and regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8b898ebfd12e66f2b3471b1fa9fd1e4
https://doi.org/10.1111/j.1474-9728.2004.00129.x
https://doi.org/10.1111/j.1474-9728.2004.00129.x
Autor:
Chariklia Petropoulou, Luca Cavallone, Claudia Giampieri, Giuseppina Carrieri, Simona Giovagnetti, Claudio Franceschi, Efstathios S. Gonos, Rosamaria Lisa, Matteo Centurelli, Elena Mugianesi, Massimiliano Bonafè, Stefano Cenerelli, Francesca Marchegiani, Maurizio Cardelli, Roberto Testa, Fabiola Olivieri, Massimo Boemi
Publikováno v:
Gene 327:2(Mar2004):215-219
The human forkhead box O1A (FOXO1A) gene belongs to the human forkhead gene family and acts downstream of the human insulin signalling pathway. In this study, polymorphisms of the Intron I of FOXO1A gene were studied in Italian healthy people and ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daed0c12becb8949ef8feeadfdec320b
https://doi.org/10.1016/j.gene.2003.11.003
https://doi.org/10.1016/j.gene.2003.11.003
Autor:
Stefania Bandinelli, Simona Giovagnetti, Claudio Franceschi, Fabiola Olivieri, Annamaria Corsi, Jack M. Guralnik, Giuseppe Paolisso, L. Ferrucci, Michelangela Barbieri, Emilia Ragno, Massimiliano Bonafè
Publikováno v:
Scopus-Elsevier
Deregulation of the inflammatory response plays a major role in the age-related decline of physical performance. The causal pathway leading from inflammation to disability has not been fully clarified, but several researches suggest that interleukin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3e65670fac176a10731e289f61be43
https://doi.org/10.1152/ajpendo.00319.2002
https://doi.org/10.1152/ajpendo.00319.2002
Autor:
Maurizio Cardelli, Claudia Giampieri, Fabiola Olivieri, Raffaella Moresi, Rosamaria Lisa, Elena Mugianesi, Massimiliano Bonafè, Francesca Marchegiani, Luca Cavallone, Simona Giovagnetti, Claudio Franceschi, Rosalia Stecconi
Publikováno v:
Experimental Gerontology. 37:309-314
IL-6 in vitro production, as well as the serum/plasma concentration of the cytokine, increase with age. In the present investigation, a total of 62 individuals (31 males and 31 females), aged from 29 to 93 years of age (mean age of males: 60.4 years;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff783aa1fb9fe648372f5166523f467
https://doi.org/10.1016/s0531-5565(01)00197-8
https://doi.org/10.1016/s0531-5565(01)00197-8
Autor:
Giuseppe Paolisso, Francesca Marchegiani, Simona Giovagnetti, Claudio Franceschi, Maurizio Marra, Massimiliano Bonafè, Maria Rosaria Rizzo, Rosmarie Lisa, Daniela Monti, Carlo Pieri, Luca Cavallone, Maurizio Cardelli, Fabiola Olivieri, Roberto Antonicelli
Publikováno v:
European Journal of Immunology. 31:2357-2361
Current literature indicates that elevated IL-6 serum levels are associated with diseases, disability and mortality in the elderly. In this paper, we studied the IL-6 promoter genetic variability at -174 C/G locus and its effect on IL-6 serum levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa5a02364e83c15795b0bac7b3a2014
https://doi.org/10.1002/1521-4141(200108)31:8<2357::aid-immu2357>3.0.co
https://doi.org/10.1002/1521-4141(200108)31:8<2357::aid-immu2357>3.0.co