Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Simona Frosali"'
Autor:
Simona Frosali, Danilo Pagliari, Giovanni Gambassi, Raffaele Landolfi, Franco Pandolfi, Rossella Cianci
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
The gut is able to maintain tolerance to microbial and food antigens. The intestine minimizes the number of harmful bacteria by shaping the microbiota through a symbiotic relationship. In healthy human intestine, a constant homeostasis is maintained
Externí odkaz:
https://doaj.org/article/996fc067313048d48a0c6b6de4752438
Autor:
Rossella Cianci, Simona Frosali, Danilo Pagliari, Paola Cesaro, Lucio Petruzziello, Fabio Casciano, Raffaele Landolfi, Guido Costamagna, Franco Pandolfi
Publikováno v:
Journal of Immunology Research, Vol 2014 (2014)
Background/Aim. Uncomplicated diverticular disease (UDD) is a frequent condition in adults. The pathogenesis of symptoms remains unknown. Bacteria are able to interact with Toll-like receptors (TLRs) and to induce inflammation through both innate imm
Externí odkaz:
https://doaj.org/article/95d8d7ea308b4b7f8eecd2cfa7f7a0ff
Autor:
Lucia Coppo, Simona Scheggi, Graziella DeMontis, Raffaella Priora, Simona Frosali, Antonio Margaritis, Domenico Summa, Danila Di Giuseppe, Monica Ulivelli, Paolo Di Simplicio
Publikováno v:
Antioxidantsredox signaling.
Increased plasma concentrations of total homocysteine (tHcy) (mild-moderate hyperhomocysteinemia: 15-50 µM tHcy) are considered an independent risk factor for onset/progression of various diseases, but it is not known how the increase in tHcy causes
Autor:
Lucia Coppo, Domenico Summa, Monica Ulivelli, Danila Di Giuseppe, Simona Frosali, Paolo Di Simplicio, Antonios Margaritis, Raffaella Priora, Sabina Bartalini
Publikováno v:
Amino Acids. 46:429-439
In hyperhomocysteinemic patients, after reaction with homocysteine-albumin mixed disulfides (HSS-ALB), mesna (MSH) forms the mixed disulfide with Hcy (HSSM) which can be removed by renal clearance, thus reducing the plasma concentration of total homo
Publikováno v:
Clinical therapeutics. 38(5)
Purpose This review aimed to take stock of the current status of research on damage-associated molecular pattern (DAMP) protein. We discuss the Janus-faced role of DAMP molecules in inflammation, cancer, and tissue repair. The high-mobility group box
Autor:
Paolo Di Simplicio, Antonios Margaritis, Raffaella Priora, Lucia Coppo, Monica Ulivelli, Danila Di Giuseppe, Giuseppe Martini, Simona Frosali, Alfonso Cerase, Domenico Summa, Sabina Bartalini
The toxicity risk of hyperhomocysteinemia is prevented through thiol drug administration which reduces plasma total homocysteine (tHcy) concentrations by activating thiol exchange reactions. Assuming that cysteine (Cys) is a homocysteinemia regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f862a3466c04eaa2e199d29b961e94c0
http://hdl.handle.net/11365/1026414
http://hdl.handle.net/11365/1026414
Autor:
Lucia Coppo, G. P. Pessina, Domenico Summa, Paolo Di Simplicio, Danila Di Giuseppe, Antonios Margaritis, Carlo Aldinucci, Raffaella Priora, Simona Frosali, Anna Di Stefano
Publikováno v:
Pharmacological Research. 64:289-297
Three different NO donors, S-nitrosoglutathione (GSNO), sodium nitroprusside (SNP) and 3-morpholino-sydnonimine hydrochloride (SIN-1) were used in order to investigate mechanisms of platelet inhibition through cGMP-dependent and -independent pathways
Publikováno v:
Experimental Biology and Medicine. 235:1114-1125
We compared the ability of pure lycopene (Lyco) versus lycopene phytocomplex (LycoC) to induce apoptosis in vitro. We found that LycoC, but not Lyco, was able to trigger apoptosis in HL60 cells, as documented by subdiploid DNA content and phosphatidy
Autor:
Lucia Coppo, Paolo Di Simplicio, Simona Frosali, Antonios Margaritis, Raffaella Priora, Jongyun Heo, Domenico Summa, Danila Di Giuseppe
Publikováno v:
Toxicology and Applied Pharmacology. 242:333-343
Protein thiol modifications including cysteinylation (CSSP) and glutathionylation (GSSP) in erythrocytes of rat treated with diamide have been reported, but mechanism and origin of CSSP formation are unknown. Experiments were performed to relate CSSP
Publikováno v:
Mini reviews in medicinal chemistry. 16(3)
We review our experience on Rifaximin in uncomplicated diverticular disease. Our data show that a 2 week treatment induces modifications in the immune system: local mucosal lymphocytes with TLR-4 were increased. In the peripheral blood CD103 cells, w