Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Simona F. Spampinato"'
Autor:
Martina Beneventano, Simona F. Spampinato, Sara Merlo, Mariangela Chisari, Paola Platania, Marco Ragusa, Michele Purrello, Ferdinando Nicoletti, Maria Angela Sortino
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Metabotropic glutamate (mGlu) receptor 5 is involved in neuroinflammation and has been shown to mediate reduced inflammation and neurotoxicity and to modify microglia polarization. On the other hand, blockade of mGlu5 receptor results in inhibition o
Externí odkaz:
https://doaj.org/article/9d76198e74ae45eab62d6f57bc48a592
Autor:
Giuseppe Caruso, Claudia G. Fresta, Nicolò Musso, Mariaconcetta Giambirtone, Margherita Grasso, Simona F. Spampinato, Sara Merlo, Filippo Drago, Giuseppe Lazzarino, Maria A. Sortino, Susan M. Lunte, Filippo Caraci
Publikováno v:
Cells, Vol 8, Iss 1, p 64 (2019)
Carnosine (β-alanyl-L-histidine), a dipeptide, is an endogenous antioxidant widely distributed in excitable tissues like muscles and the brain. Carnosine is involved in cellular defense mechanisms against oxidative stress, including the inhibition o
Externí odkaz:
https://doaj.org/article/6576816879f04530b4ef9a943001353d
Autor:
Filippo, Caraci, Fabio, Tascedda, Sara, Merlo, Cristina, Benatti, Simona F, Spampinato, Antonio, Munafò, Gian Marco, Leggio, Ferdinando, Nicoletti, Nicoletta, Brunello, Filippo, Drago, Maria Angela, Sortino, Agata, Copani
Publikováno v:
Frontiers in Pharmacology
Selective reuptake inhibitors (SSRIs), such as fluoxetine and sertraline, increase circulating Transforming-Growth-Factor-β1 (TGF-β1) levels in depressed patients, and are currently studied for their neuroprotective properties in Alzheimer’s dise
Autor:
Simona F Spampinato, Birgit Obermeier, Anne Cotleur, Anna Love, Yukio Takeshita, Yasuteru Sano, Takashi Kanda, Richard M Ransohoff
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133392 (2015)
The ability of the Blood Brain Barrier (BBB) to maintain proper barrier functions, keeping an optimal environment for central nervous system (CNS) activity and regulating leukocytes' access, can be affected in CNS diseases. Endothelial cells and astr
Externí odkaz:
https://doaj.org/article/1b6f677fc1694ae2a37b6691c600442e