Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Simona De Summa"'
Autor:
Stefania Martino, Simona De Summa, Brunella Pilato, Maria Digennaro, Letizia Laera, Stefania Tommasi, Margherita Patruno
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The gene protection of telomere 1 (POT1) is involved in telomere maintenance and stability and plays a crucial role in the preservation of genomic stability. POT1 is considered a high-penetrance melanoma susceptibility gene; however, the number of ca
Externí odkaz:
https://doaj.org/article/79fdfc99c2374daf9642fab4a291a3b4
Autor:
Elsa Vitale, Alessandro Rizzo, Lorenza Maistrello, Patrizia Nardulli, Tiziana Talienti, Davide Quaresmini, Simona De Summa, Raffaella Massafra, Nicola Silvestris, Oronzo Brunetti
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundWe performed a systematic review and meta-analysis to further explore the impact of the addition of immunotherapy to gemcitabine–cisplatin as first-line treatment for advanced biliary tract cancer (BTC) patients.MethodsLiterature research
Externí odkaz:
https://doaj.org/article/8a657111b7b94433986614971289368c
Autor:
Simona Serratì, Roberta Di Fonte, Letizia Porcelli, Simona De Summa, Ivana De Risi, Livia Fucci, Eustachio Ruggieri, Tommaso Maria Marvulli, Sabino Strippoli, Rossella Fasano, Tania Rafaschieri, Gabriella Guida, Michele Guida, Amalia Azzariti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background Clinical drawback in checkpoint inhibitors immunotherapy (ICI) of metastatic melanoma (MM) is monitoring clinical benefit. Soluble forms of PD1(sPD1) and PD-L1(sPD-L1) and extracellular vesicles (EVs) expressing PD1 and PD-L1 have
Externí odkaz:
https://doaj.org/article/2b5cecf7a196430a882f23e37244ba42
Autor:
Vito Longo, Carminia Maria Della Corte, Alessandro Russo, Francesca Spinnato, Francesca Ambrosio, Riccardo Ronga, Antonella Marchese, Teresa Del Giudice, Concetta Sergi, Francesca Casaluce, Marina Gilli, Michele Montrone, Valerio Gristina, Vincenzo Sforza, Maria Lucia Reale, Raimondo Di Liello, Alberto Servetto, Helga Lipari, Claudio Longhitano, Laura Vizzini, Anna Manzo, Antonella Cristofano, Loretta Paolelli, Annalisa Nardone, Simona De Summa, Antonella Perrone, Carmela Bisceglia, Caterina Derosa, Valerio Nardone, Giuseppe Viscardi, Domenico Galetta, Fabiana Vitiello
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundConsolidative thoracic radiotherapy (TRT) has been commonly used in the management of extensive-stage small cell lung cancer (ES-SCLC). Nevertheless, phase III trials exploring first-line chemoimmunotherapy have excluded this treatment appr
Externí odkaz:
https://doaj.org/article/0916d9972ccf47d690c1cb596c1e055d
Autor:
Simona De Summa, Debora Traversa, Antonella Daniele, Orazio Palumbo, Massimo Carella, Raffaella Stallone, Antonio Tufaro, Andreina Oliverio, Eleonora Bruno, Maria Digennaro, Katia Danza, Patrizia Pasanisi, Stefania Tommasi
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundBreast cancer onset is determined by a genetics-environment interaction. BRCA1/2 gene alterations are often genetically shared in familial context, but also food intake and hormonal assessment seem to influence the lifetime risk of developi
Externí odkaz:
https://doaj.org/article/df766af27fde48da81be1b838199c8e7
Autor:
Katia Danza, Letizia Porcelli, Simona De Summa, Roberta Di Fonte, Brunella Pilato, Rosanna Lacalamita, Simona Serratì, Amalia Azzariti, Stefania Tommasi
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 904-920 (2022)
Vitamin D is used to reduce cancer risk and improve the outcome of cancer patients, but the vitamin D receptor (VDR; also known as the calcitriol receptor) pathway needs to be functionally intact to ensure the biological effects of circulating calcit
Externí odkaz:
https://doaj.org/article/4a3c78e8a74c4d76a4b251811673088b
Autor:
Simona Serratì, Michele Guida, Roberta Di Fonte, Simona De Summa, Sabino Strippoli, Rosa Maria Iacobazzi, Alessandra Quarta, Ivana De Risi, Gabriella Guida, Angelo Paradiso, Letizia Porcelli, Amalia Azzariti
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-18 (2022)
Abstract Background The immunotherapy with immune checkpoints inhibitors (ICI) has changed the life expectancy in metastatic melanoma (MM) patients. Nevertheless, several patients do not respond hence, the identification and validation of novel bioma
Externí odkaz:
https://doaj.org/article/bb0f7e675ead4af9bb663a4eb45ed84e
Autor:
Lucia Di Nardo, Cristina Pellegrini, Alessandro Di Stefani, Francesco Ricci, Barbara Fossati, Laura Del Regno, Carmine Carbone, Geny Piro, Vincenzo Corbo, Pietro Delfino, Simona De Summa, Maria Giovanna Maturo, Tea Rocco, Giampaolo Tortora, Maria Concetta Fargnoli, Ketty Peris
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract A number of genes have been implicated in the pathogenesis of BCC in addition to the Hedgehog pathway, which is known to drive the initiation of this tumour. We performed in-depth analysis of 13 BCC-related genes (CSMD1, CSMD2, DPH3 promoter
Externí odkaz:
https://doaj.org/article/42184938104c4252943a7b251521a537
Autor:
Nicola Altini, Emilia Puro, Maria Giovanna Taccogna, Francescomaria Marino, Simona De Summa, Concetta Saponaro, Eliseo Mattioli, Francesco Alfredo Zito, Vitoantonio Bevilacqua
Publikováno v:
Bioengineering, Vol 10, Iss 4, p 396 (2023)
The segmentation and classification of cell nuclei are pivotal steps in the pipelines for the analysis of bioimages. Deep learning (DL) approaches are leading the digital pathology field in the context of nuclei detection and classification. Neverthe
Externí odkaz:
https://doaj.org/article/ad99363331c948249ed69c3ae29f1b5d
Autor:
Letizia Andresciani, Concetta Calabrò, Mariarita Laforgia, Maria Ronchi, Simona De Summa, Christel Cariddi, Rosa Boccuzzi, Anna De Rosa, Elisabetta Rizzo, Giulia Losito, Grazia Bradascio, Gaetano Napoli, Michele Simone, Giuseppe Carravetta, Giovanni Mastrandrea
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The complexity of cancer patients and the use of advanced and demolitive surgical techniques frequently need post-operatory ICU hospitalization. To increase safety and to select the best medical strategies for the patient, a multidisciplinary team ha
Externí odkaz:
https://doaj.org/article/d408a6a5df554f409f8ed62b65dadc1f