Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Simona Caruso"'
Autor:
Simona Manni, Francesca Del Bufalo, Pietro Merli, Domenico Alessandro Silvestris, Marika Guercio, Simona Caruso, Sofia Reddel, Laura Iaffaldano, Michele Pezzella, Stefano Di Cecca, Matilde Sinibaldi, Alessio Ottaviani, Maria Cecilia Quadraccia, Mariasole Aurigemma, Andrea Sarcinelli, Roselia Ciccone, Zeinab Abbaszadeh, Manuela Ceccarelli, Rita De Vito, Maria Chiara Lodi, Maria Giuseppina Cefalo, Angela Mastronuzzi, Biagio De Angelis, Franco Locatelli, Concetta Quintarelli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Chimeric antigen receptor T (CAR-T) cell therapy may achieve long-lasting remission in patients with B-cell malignancies not responding to conventional therapies. However, potentially severe and hard-to-manage side effects, including cytokin
Externí odkaz:
https://doaj.org/article/e13fedf5b3e94ec1a443079d5e0501e7
Autor:
Simona Caruso, Biagio De Angelis, Francesca Del Bufalo, Roselia Ciccone, Samantha Donsante, Gabriele Volpe, Simona Manni, Marika Guercio, Michele Pezzella, Laura Iaffaldano, Domenico Alessandro Silvestris, Matilde Sinibaldi, Stefano Di Cecca, Angela Pitisci, Enrico Velardi, Pietro Merli, Mattia Algeri, Mariachiara Lodi, Valeria Paganelli, Marta Serafini, Mara Riminucci, Franco Locatelli, Concetta Quintarelli
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-19 (2022)
Abstract Background Paediatric acute myeloid leukaemia (AML) is characterized by poor outcomes in patients with relapsed/refractory disease, despite the improvements in intensive standard therapy. The leukaemic cells of paediatric AML patients show h
Externí odkaz:
https://doaj.org/article/a538e2a7f35741f4b65eb6ac393adde9
Autor:
Marika Guercio, Simona Manni, Iolanda Boffa, Simona Caruso, Stefano Di Cecca, Matilde Sinibaldi, Zeinab Abbaszadeh, Antonio Camera, Roselia Ciccone, Vinicia Assunta Polito, Francesca Ferrandino, Sofia Reddel, Maria Luigia Catanoso, Emilia Bocceri, Francesca Del Bufalo, Mattia Algeri, Biagio De Angelis, Concetta Quintarelli, Franco Locatelli
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T cells engineered with chimeric antigen receptor (CAR-T cells) are an effective treatment in patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia or B-cell non-Hodgkin lymphoma. Despite the reported exciting clinical resul
Externí odkaz:
https://doaj.org/article/22257a3336434483b101ea658433576b
Autor:
Marco Ruella, Valentina Bertaina, Franco Locatelli, Antonio Camera, Biagio De Angelis, Francesca Del Bufalo, Concetta Quintarelli, Pietro Merli, Marika Guercio, Simona Manni, Iolanda Boffa, Matilde Sinibaldi, Stefano Di Cecca, Simona Caruso, Zeinab Abbaszadeh, Biancamaria Cembrola, Roselia Ciccone, Alberto Orfao, Lourdes Martin-Martin, Sara Gutierrez-Herrero, Maria Herrero-Garcia, Gianni Cazzaniga, Vittorio Nunes, Simona Songia, Paolo Marcatili, Frederikke I Marin, Luciana Vinti, Mattia Algeri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Methods We evaluated the impact of a high percentage of leukemia blast contamination in patient-derived starting material (SM) on CAR T-cell drug product (DP) manufacturing. In vitro as well as in vivo models were employed to identify char
Externí odkaz:
https://doaj.org/article/fc993e58dfde4d03ab19898c5289c470
Autor:
Marika Guercio, Domenico Orlando, Stefano Di Cecca, Matilde Sinibaldi, Iolanda Boffa, Simona Caruso, Zeinab Abbaszadeh, Antonio Camera, Biancamaria Cembrola, Katia Bovetti, Simona Manni, Ignazio Caruana, Roselia Ciccone, Francesca Del Bufalo, Pietro Merli, Luciana Vinti, Katia Girardi, Annalisa Ruggeri, Cristiano De Stefanis, Marco Pezzullo, Ezio Giorda, Marco Scarsella, Rita De Vito, Sabina Barresi, Andrea Ciolfi, Marco Tartaglia, Lorenzo Moretta, Franco Locatelli, Concetta Quintarelli, Biagio De Angelis
Publikováno v:
Haematologica, Vol 106, Iss 4 (2020)
The prognosis of many patients with chemotherapy-refractory or multiply relapsed CD30+ non-Hodgkin Lymphoma (NHL) or Hodgkin lymphoma (HL) still remains poor, and novel therapeutic approaches are warranted to address this unmet clinical need. In ligh
Externí odkaz:
https://doaj.org/article/47f7780fa4f341798474cf24f1f0e5d0
Sediment mobility is one of the key issues considered during the design and construction process off offshore infrastructure ( Wind farms, cables, pipelines etc.). Early understanding of the seabed mobility can significantly affect the project timeli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b7c80d2709442a822efa8ef70a3fecf
https://doi.org/10.5194/egusphere-egu23-16716
https://doi.org/10.5194/egusphere-egu23-16716
Autor:
Concetta Quintarelli, Franco Locatelli, Elisabetta Ferretti, Angela Mastronuzzi, Felice Giangaspero, Mirjam H.M. Heemskerk, Renate S. Hagedoorn, Annemarie Moseley, Antonio Camera, Simona Caruso, Andrea Carai, Luana Abballe, Ignazio Caruana, Agnese Po, Matilde Sinibaldi, Iolanda Boffa, Marika Guercio, Biagio De Angelis, Evelina Miele, Domenico Orlando
TABLE S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e1a57a8217fa6a364b5240986103f8
https://doi.org/10.1158/0008-5472.22419360
https://doi.org/10.1158/0008-5472.22419360
Autor:
Concetta Quintarelli, Franco Locatelli, Elisabetta Ferretti, Angela Mastronuzzi, Felice Giangaspero, Mirjam H.M. Heemskerk, Renate S. Hagedoorn, Annemarie Moseley, Antonio Camera, Simona Caruso, Andrea Carai, Luana Abballe, Ignazio Caruana, Agnese Po, Matilde Sinibaldi, Iolanda Boffa, Marika Guercio, Biagio De Angelis, Evelina Miele, Domenico Orlando
Medulloblastoma is the most frequent malignant childhood brain tumor with a high morbidity. Identification of new therapeutic targets would be instrumental in improving patient outcomes. We evaluated the expression of the tumor-associated antigen PRA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd155452f1bc1ba89568fe062679db0e
https://doi.org/10.1158/0008-5472.c.6510363.v1
https://doi.org/10.1158/0008-5472.c.6510363.v1
Autor:
Simona Manni, Francesca Del Bufalo, Pietro Merli, Domenico Alessandro Silvestris, Marika Guercio, Simona Caruso, Sofia Reddel, Laura Iaffaldano, Michele Pezzella, Stefano Di Cecca, Matilde Sinibaldi, Alessio Ottaviani, Maria Cecilia Quadraccia, Mariasole Aurigemma, Andrea Sarcinelli, Roselia Ciccone, Zeinab Abbaszadeh, Manuela Ceccarelli, Rita De Vito, Maria Chiara Lodi, Maria Giuseppina Cefalo, Angela Mastronuzzi, Biagio De Angelis, Franco Locatelli, Concetta Quintarelli
Chimeric antigen receptor (CAR) T-cell therapy represents a revolutionary approach to induce long-lasting remission in patients with B-cell malignancies not responding to conventional therapies. Nevertheless, possible severe side effects, including c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794ebdffc6d89067008d2f1424cecfad
https://doi.org/10.21203/rs.3.rs-1482837/v1
https://doi.org/10.21203/rs.3.rs-1482837/v1
Autor:
Emmanuel de Billy, Marsha Pellegrino, Domenico Orlando, Giulia Pericoli, Roberta Ferretti, Pietro Businaro, Maria Antonietta Ajmone-Cat, Sabrina Rossi, Lucia Lisa Petrilli, Nicola Maestro, Francesca Diomedi-Camassei, Marco Pezzullo, Cristiano De Stefanis, Paola Bencivenga, Alessia Palma, Rossella Rota, Francesca Del Bufalo, Luca Massimi, Gerrit Weber, Chris Jones, Andrea Carai, Simona Caruso, Biagio De Angelis, Ignazio Caruana, Concetta Quintarelli, Angela Mastronuzzi, Franco Locatelli, Maria Vinci
Publikováno v:
Neuro-Oncology. 24:1150-1163
BackgroundDiffuse midline gliomas (DMG) H3K27M-mutant, including diffuse intrinsic pontine glioma (DIPG), are pediatric brain tumors associated with grim prognosis. Although GD2-CAR T-cells demonstrated significant anti-tumor activity against DMG H3K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40e98f616965166ec05f8163095689a
https://doi.org/10.1093/neuonc/noab300
https://doi.org/10.1093/neuonc/noab300