Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Simona Camero"'
Autor:
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel, Francesca Antonella Aiello, Francesca Vulcano, Luisa Milazzo, Simona Camero, Deborah Pajalunga, Massimo Spada, Valeria Manzi, Giovanni Luca Gravina, Silvia Codenotti, Michela Piccione, Miriam Tomaciello, Michele Signore, Giovanni Barillari, Cinzia Marchese, Alessandro Fanzani, Biagio De Angelis, Concetta Quintarelli, Christopher R. Vakoc, Eleanor Y. Chen, Francesca Megiorni, Franco Locatelli, Sergio Valente, Antonello Mai, Rossella Rota, Francesco Marampon
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-20 (2024)
Abstract Radiotherapy (RT) plays a critical role in the management of rhabdomyosarcoma (RMS), the prevalent soft tissue sarcoma in childhood. The high risk PAX3-FOXO1 fusion-positive subtype (FP-RMS) is often resistant to RT. We have recently demonst
Externí odkaz:
https://doaj.org/article/d2578a217b0d469480a398078bb622c7
Autor:
Simona Camero, Luisa Milazzo, Francesca Vulcano, Federica Ceccarelli, Paola Pontecorvi, Francesca Pedini, Alessandra Rossetti, Elena Sofia Scialis, Giulia Gerini, Fabrizio Cece, Silvia Pomella, Matteo Cassandri, Antonella Porrazzo, Enrico Romano, Claudio Festuccia, Giovanni Luca Gravina, Simona Ceccarelli, Rossella Rota, Lavinia Vittoria Lotti, Fabio Midulla, Antonio Angeloni, Cinzia Marchese, Francesco Marampon, Francesca Megiorni
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-24 (2024)
Abstract Background Despite a multimodal approach including surgery, chemo- and radiotherapy, the 5-year event-free survival rate for rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in childhood, remains very poor for metastatic patients,
Externí odkaz:
https://doaj.org/article/0b81896720af4a4a9845e88f03e04c18
Autor:
Sara Vaccaro, Alessandra Rossetti, Antonella Porrazzo, Simona Camero, Matteo Cassandri, Silvia Pomella, Miriam Tomaciello, Giampiero Macioce, Francesca Pedini, Giovanni Barillari, Cinzia Marchese, Rossella Rota, Giovanni Cenci, Mario Tombolini, Robert A. Newman, Peiying Yang, Silvia Codenotti, Alessandro Fanzani, Francesca Megiorni, Claudio Festuccia, Giuseppe Minniti, Giovanni Luca Gravina, Francesca Vulcano, Luisa Milazzo, Francesco Marampon
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Treatment of rhabdomyosarcoma (RMS), the most common a soft tissue sarcoma in childhood, provides intensive multimodal therapy, with radiotherapy (RT) playing a critical role for local tumor control. However, since RMS efficiently activates mechanism
Externí odkaz:
https://doaj.org/article/35544f0854274470951c3529077bc1d1
Autor:
Simona Camero, Matteo Cassandri, Silvia Pomella, Luisa Milazzo, Francesca Vulcano, Antonella Porrazzo, Giovanni Barillari, Cinzia Marchese, Silvia Codenotti, Miriam Tomaciello, Rossella Rota, Alessandro Fanzani, Francesca Megiorni, Francesco Marampon
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Management of rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children, frequently accounting the genitourinary tract is complex and requires a multimodal therapy. In particular, as a consequence of the advancement in dose conformity t
Externí odkaz:
https://doaj.org/article/6ae4c65046c24c3fbce7b1e3457a09c9
Autor:
Clara Perrone, Silvia Pomella, Matteo Cassandri, Michele Pezzella, Giuseppe Maria Milano, Marta Colletti, Cristina Cossetti, Giulia Pericoli, Angela Di Giannatale, Emmanuel de Billy, Maria Vinci, Stefania Petrini, Francesco Marampon, Concetta Quintarelli, Riccardo Taulli, Josep Roma, Soledad Gallego, Simona Camero, Paolo Mariottini, Manuela Cervelli, Roberta Maestro, Lucio Miele, Biagio De Angelis, Franco Locatelli, Rossella Rota
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Rhabdomyosarcoma (RMS) is a pediatric myogenic soft tissue sarcoma. The Fusion-Positive (FP) subtype expresses the chimeric protein PAX3-FOXO1 (P3F) while the Fusion-Negative (FN) is devoid of any gene translocation. FP-RMS and metastatic FN-RMS are
Externí odkaz:
https://doaj.org/article/ee3525baf2b04329b1397817076f26b7
Autor:
Francesco Petragnano, Ilaria Pietrantoni, Simona Camero, Silvia Codenotti, Luisa Milazzo, Francesca Vulcano, Giampiero Macioce, Ilenia Giordani, Paolo Tini, Sara Cheleschi, Giovanni Luca Gravina, Claudio Festuccia, Alessandra Rossetti, Simona Delle Monache, Alessandra Ordinelli, Carmela Ciccarelli, Annunziata Mauro, Barboni Barbara, Cristina Antinozzi, Amalia Schiavetti, Roberto Maggio, Luigi Di Luigi, Antonella Polimeni, Cinzia Marchese, Vincenzo Tombolini, Alessandro Fanzani, Nicola Bernabò, Francesca Megiorni, Francesco Marampon
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-18 (2020)
Abstract Background The probability of local tumor control after radiotherapy (RT) remains still miserably poor in pediatric rhabdomyosarcoma (RMS). Thus, understanding the molecular mechanisms responsible of tumor relapse is essential to identify pe
Externí odkaz:
https://doaj.org/article/6c60768f760542368bab33f512e1c44b
Autor:
Enrica Vescarelli, Giulia Gerini, Francesca Megiorni, Eleni Anastasiadou, Paola Pontecorvi, Luciana Solito, Claudia De Vitis, Simona Camero, Claudia Marchetti, Rita Mancini, Pierluigi Benedetti Panici, Carlo Dominici, Ferdinando Romano, Antonio Angeloni, Cinzia Marchese, Simona Ceccarelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-15 (2020)
Abstract Background Ovarian cancer (OC) is the most lethal gynecological malignancy and the second leading cause of cancer-related death in women. Treatment with PARP inhibitors (PARPi), such as Olaparib, has been recently introduced for OC patients,
Externí odkaz:
https://doaj.org/article/44a1df77c3704f56baee7d518d8349e0
Autor:
Eleni Anastasiadou, Simona Ceccarelli, Elena Messina, Giulia Gerini, Francesca Megiorni, Paola Pontecorvi, Simona Camero, Maria Giuseppina Onesti, Pankaj Trivedi, Mario Faenza, Enrico Coscioni, Giovanni Francesco Nicoletti, Claudio Napoli, Cinzia Marchese
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257070 (2021)
Adipose-derived mesenchymal stem cells (ASCs) are promising therapeutic tools in regenerative medicine because they possess self-renewal, differentiation and immunomodulatory capacities. After isolation, ASCs are passaged multiple times in vitro pass
Externí odkaz:
https://doaj.org/article/130fb854da61478d8bc50f8d95f23915
Autor:
Simona Camero, Giulia Vitali, Paola Pontecorvi, Simona Ceccarelli, Eleni Anastasiadou, Francesca Cicchetti, Elisabetta Flex, Silvia Pomella, Matteo Cassandri, Rossella Rota, Francesco Marampon, Cinzia Marchese, Amalia Schiavetti, Francesca Megiorni
Publikováno v:
Cells, Vol 10, Iss 11, p 2956 (2021)
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood. Recently, we demonstrated the overexpression of both DNA methyltransferase 3A (DNMT3A) and 3B (DNMT3B) in RMS tumour biopsies and cell lines compared to normal skeletal muscl
Externí odkaz:
https://doaj.org/article/664cd9295ee447589ec4efc14f072f15
Autor:
Francesca Megiorni, Giovanni Luca Gravina, Simona Camero, Simona Ceccarelli, Andrea Del Fattore, Vincenzo Desiderio, Federica Papaccio, Heather P. McDowell, Rajeev Shukla, Antonio Pizzuti, Filip Beirinckx, Philippe Pujuguet, Laurent Saniere, Ellen Van der Aar, Roberto Maggio, Francesca De Felice, Cinzia Marchese, Carlo Dominici, Vincenzo Tombolini, Claudio Festuccia, Francesco Marampon
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-19 (2017)
Abstract Background EPH (erythropoietin-producing hepatocellular) receptors are clinically relevant targets in several malignancies. This report describes the effects of GLPG1790, a new potent pan-EPH inhibitor, in human embryonal rhabdomyosarcoma (E
Externí odkaz:
https://doaj.org/article/c2ec0ef788624ddf8f31c6257cf4ffc9