Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Simona Blotta"'
Publikováno v:
Biologics: Targets & Therapy, Vol 2008, Iss Issue 3, Pp 419-431 (2008)
Aldo M Roccaro1, Irene M Ghobrial1, Simona Blotta1, Steven P Treon1, Michele Malagola2, Kenneth C Anderson1, Paul G Richardson1, Domenico Russo21Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA;
Externí odkaz:
https://doaj.org/article/bad66ef67c3943c793fa1f520c88a596
Autor:
Jana Jakubikova, David Cervi, Melissa Ooi, Kihyun Kim, Sabikun Nahar, Steffen Klippel, Dana Cholujova, Merav Leiba, John F. Daley, Jake Delmore, Joseph Negri, Simona Blotta, Douglas W. McMillin, Teru Hideshima, Paul G. Richardson, Jan Sedlak, Kenneth C. Anderson, Constantine S. Mitsiades
Publikováno v:
Haematologica, Vol 96, Iss 8 (2011)
Background Isothiocyanates, a family of phytochemicals found in cruciferous vegetables, have cytotoxic effects against several types of tumor cells. Multiple myeloma is a fatal disease characterized by clonal proliferation of plasma cells in the bone
Externí odkaz:
https://doaj.org/article/6ecdffc9d691420c9800454442ed5225
Autor:
Giovanni Martinelli, Armando Santoro, Carlo Gambacorti-Passerini, Susana Vives Polo, Scott R. Solomon, Sudipto Mukherjee, Ewa Lech-Maranda, Moshe Yair Levy, Agnieszka Wierzbowska, María Calbacho-Robles, Giovanni Marconi, Maria Benedetta Giannini, Isabel Cano, Laura Torres Miñana, Evelyn Acuña-Cruz, Noemi Angelosanto, Tariq I. Mughal, Antonio Galleu, Simona Blotta, Farhad Ravandi, Pau Montesinos
Publikováno v:
Clinical lymphoma, myeloma & leukemia
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Context: Mutations in the FLT3 tyrosine kinase and in IDH1/IDH2 (collectively IDHm) co-occur in up to 30% of adults with acute myeloid leukemia (AML). SEL24/MEN1703 is an orally available, first-in-class, dual PIM/FLT3 kinase inhibitor. Preliminary r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8cad985ce732618e14f993793fb0cf
https://hdl.handle.net/10281/411245
https://hdl.handle.net/10281/411245
Autor:
Giovanni Martinelli, Armando Santoro, Carlo Gambacorti-Passerini, Susana Vives Polo, Scott R. Solomon, Sudipto Mukherjee, Ewa Lech-Maranda, Moshe Yair Levy, Agnieszka Wierzbowska, María Calbacho-Robles, Giovanni Marconi, Maria Benedetta Giannini, Isabel Cano, Laura Torres Miñana, Evelyn Acuña-Cruz, Noemi Angelosanto, Tariq I. Mughal, Antonio Galleu, Simona Blotta, Farhad Ravandi, Pau Montesinos
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::740bf7a63dd56de86f02bde578458718
https://doi.org/10.1016/s2152-2650(22)00831-x
https://doi.org/10.1016/s2152-2650(22)00831-x
Autor:
Giovanni Martinelli, Armando Santoro, Carlo Gambacorti-Passerini, Susana Vives Polo, Scott R. Solomon, Sudipto Mukherjee, M. Yair Levy, Agnieszka Wierzbowska, Maria Calbacho, Noemi Angelosanto, Antonio Galleu, Simone Baldini, Simona Blotta, Nassir Habboubi, Farhad Ravandi, Pau Montesinos
Publikováno v:
Journal of Clinical Oncology. 40:7024-7024
7024 Background: Mutations in the FLT3 tyrosine kinase are the most frequent ones that occur in adults with acute myeloid leukemia (AML) and can co-occur with mutations in IDH1 or IDH2 (collectively IDHm) in up to 30% of cases. SEL24/MEN1703 is an or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c506e707e5ff91a38f9feca46d807f
https://doi.org/10.1200/jco.2022.40.16_suppl.7024
https://doi.org/10.1200/jco.2022.40.16_suppl.7024
Autor:
Constantine S. Mitsiades, David Cervi, Teru Hideshima, Paul G. Richardson, Jan Sedlak, Steffen Klippel, Sabikun Nahar, Dana Cholujova, Simona Blotta, Kenneth C. Anderson, Merav Leiba, Jana Jakubikova, Ki-Hyun Kim, John F. Daley, Jake Delmore, Melissa G. Ooi, Joseph Negri, Douglas W. McMillin
Publikováno v:
Haematologica. 96:1170-1179
Background Isothiocyanates, a family of phytochemicals found in cruciferous vegetables, have cytotoxic effects against several types of tumor cells. Multiple myeloma is a fatal disease characterized by clonal proliferation of plasma cells in the bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09033eced0924e6461b6b9a7c022d4c8
https://doi.org/10.3324/haematol.2010.029363
https://doi.org/10.3324/haematol.2010.029363
Autor:
David Cervi, Simona Blotta, Sun-Young Kong, Jake Delmore, Melissa G. Ooi, Maria Kost-Alimova, Jacob P. Laubach, Jana Jakubikova, Constantine S. Mitsiades, Kenneth C. Anderson, Dana Cholujova, Jan Sedlak, Merav Leiba, Sophia Adamia, Paul G. Richardson, Steffen Klippel, John F. Daley
Publikováno v:
Blood. 117:4409-4419
Recurrence of multiple myeloma (MM) after therapy suggests the presence of tumor-initiating subpopulations. In our study, we performed flow cytometry–based Hoechst 33342 staining to evaluate the existence of a MM population with stem-like features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d910f758b584203c131715de081dcac
https://doi.org/10.1182/blood-2010-02-267344
https://doi.org/10.1182/blood-2010-02-267344
Autor:
Lynne Uhl, Simona Blotta, Poorvi Somaiya, Donald Kufe, James D. Levine, Baldev Vasir, Yan Emily Yuan, Edie Weller, Donna Fitzgerald, Jacalyn Rosenblatt, Nikhil C. Munshi, Karen Francoeur, Dilani Dombagoda, Kenneth C. Anderson, Zekui Wu, Paul G. Richardson, David Avigan, Claire MacNamara, Robin Joyce
Publikováno v:
Blood. 117:393-402
We have developed a tumor vaccine in which patient-derived myeloma cells are chemically fused with autologous dendritic cells (DCs) such that a broad spectrum of myeloma-associated antigens are presented in the context of DC-mediated costimulation. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749e27343a7677292d2cb404ffef4841
https://doi.org/10.1182/blood-2010-04-277137
https://doi.org/10.1182/blood-2010-04-277137
Autor:
Rao Prabhala, David Cervi, Constantine S. Mitsiades, Brunella Franco, Samir B. Amin, Klaus Podar, Kenneth C. Anderson, Nikhil C. Munshi, Alessandro Zullo, Pierfrancesco Tassone, Jana Jakubikova, Yu-Tzu Tai, Piersandro Tagliaferri, Simona Blotta
Publikováno v:
Blood; Vol 114
The transformation from monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) is thought to be associated with changes in immune processes. We have therefore used serologic analysis of recombinant cDNA expression library
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6ce2ce7ede2c6f8b692e549da47067
https://doi.org/10.1182/blood-2009-04-219436
https://doi.org/10.1182/blood-2009-04-219436
Autor:
Judith Runnels, Antonio Sacco, Hai T. Ngo, Barrett J. Rollins, Charles P. Lin, Irene M. Ghobrial, Molly R. Melhem, Costas Pitsillides, Abdel Kareem Azab, Feda Azab, Brian Thompson, Simona Blotta, Kenneth C. Anderson, Xiaoying Jia, Aldo M. Roccaro
Publikováno v:
Blood. 114:619-629
The interaction of multiple myeloma (MM) cells with the bone marrow (BM) milieu plays a crucial role in MM pathogenesis. Stromal cell–derived factor-1 (SDF1) regulates homing of MM cells to the BM. In this study, we examined the role of RhoA and Ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128b2747f4cbbe3b3d4f558686f013b6
https://doi.org/10.1182/blood-2009-01-199281
https://doi.org/10.1182/blood-2009-01-199281