Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Simona Alfonsi"'
1
Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation
Autor: Simona Alfonsi, Pedro Bullón, Adrian Gonzalez-Alonso, Rocío García-Marín, Manuel de Miguel, Mario D. Cordero, Maurizio Battino, José L. Quiles, Maria del Carmen Ramirez-Tortosa
Publikováno v: Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
BMC Medicine
BMC Medicine, Vol 10, Iss 1, p 122 (2012)
Authors are indebted with Ms Monica Glebocki for extensive editing of the manuscript
Background: Periodontitis, the most prevalent chronic inflammatory disease, has been related to cardiovascular diseases. Autophagy provides a mechanism for the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b204bf77058636659816e9d4b70904e0
http://hdl.handle.net/10481/63129
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2
HER family receptor expression and prognosis in pancreatic cancer
Autor: Chiara Pellei, Simona Alfonsi, Stefano Cascinu, Marina Scarpelli, Cristian Loretelli, Alessandro Bittoni, Francesco Piva, Andrea Lanese, Kalliopi Andrikou, Alessandra Mandolesi, Matteo Santoni
Publikováno v: The International journal of biological markers. 30(3)
BackgroundHER family receptors play a key role in tumor progression in several malignancies, such as colorectal, lung or breast cancer. The aims of this study were to investigate expression of HER-1, HER-2 and HER-3 in pancreatic cancer (PC) samples
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e2d6b88363955c352e11b63c8e52ae
https://pubmed.ncbi.nlm.nih.gov/26109364
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3
Beyond the intestinal celiac mucosa: diagnostic role of anti TG2 deposits, a systematic review
Autor: Simona Gatti, Giovanni Cobellis, M. Rossi, Simona Alfonsi, Alessandra Mandolesi, Carlo Catassi
Publikováno v: Frontiers in Medicine, Vol 1 (2014)
Frontiers in Medicine
Aim: to review the existing literature on the role and significance of intestinal transglutaminase 2 IgA deposits (TG2 deposits) in patients with overt CD, potential CD and other autoimmune or gluten-related conditions. Methods: we conducted a system
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fe87413bd5c92729ad2d566ca89f02
http://journal.frontiersin.org/Journal/10.3389/fmed.2014.00009/full
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4
Primary intra-abdominal synovial sarcoma: a case report
Autor: Grazia, Travaglini, Simona, Biagetti, Simona, Alfonsi, Italo, Bearzi, Cristina, Marmorale
Publikováno v: Annali italiani di chirurgia. 84
The authors report a case of intra-abdominal synovial-sarcoma of the gastrocolic ligament in a 64-years-old woman hospitalized for a palpable abdominal mass and pain. CT scan detected an intra-abdominal mass extended through the abdominal wall into t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::72d72a777603cea288b1af1e1a41e2f1
https://pubmed.ncbi.nlm.nih.gov/24505604
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5
Prognostic Factors in Pancreatic Cancer: The Role of Perineural, Vascular and Lymphatic Invasion and of Ca19-9
Autor: olesi A, Miriam Caramanti, Alessandra Lucarelli, Azzurra Onofri, Stefano Cascinu, Pellei C, Simona Alfonsi, Agnese Savini, Bearzi I, Elena Maccaroni, Rossana Berardi, Simona Biagetti
Publikováno v: Journal of Gastrointestinal & Digestive System.
Objective: The aim of our analysis was to investigate the impact of perineural, vascular and lymphatic invasion and of CA19-9 on survival in patients with locally advanced and metastatic pancreatic cancer, with the objective to serve as a tool for a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26ab1c7cdbf39477c31d28efd109872f
https://doi.org/10.4172/2161-069x.1000134
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6
Role of β4 integrin in HER-3-negative, K-RAS wild-type metastatic colorectal tumors receiving cetuximab
Autor: Mario Scartozzi, Italo Bearzi, Luca Faloppi, Alessandra Mandolesi, Cristian Loretelli, Maristella Bianconi, M. Del Prete, Stefano Cascinu, Alessandro Bittoni, Riccardo Giampieri, Simona Biagetti, Simona Alfonsi
Aims: Altered α6β4 integrin expression has been demonstrated in HER-3-negative tumors and may be responsible for anti-HER treatment resistance. The current study aimed to evaluate the interaction between polymorphisms of α6 and β4 integrins and c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6dc52a5afb31fad5916768766cea5c2
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7
Is inflammation a mitochondrial dysfunction-dependent event in fibromyalgia?
Autor: Pedro Bullón, Mario D. Cordero, Manuel de Miguel, Angel M. Carrión, José Antonio Sánchez-Alcázar, Eduardo Díaz-Parrado, Simona Alfonsi, Maurizio Battino
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Fibromyalgia (FM) is a complex disorder that affects up to 5% of the general population worldwide. Both mitochondrial dysfunction and inflammation have been implicated in the pathophysiology of FM. We have investigated the possible relationship betwe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8880414399692eb23115fc4943475cfa
https://pubmed.ncbi.nlm.nih.gov/22938055
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8
Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab
Autor: Alessandra Mandolesi, Michela Del Prete, Italo Bearzi, Simona Biagetti, Alessandro Bittoni, Lucio Giustini, Mario Scartozzi, Luca Faloppi, Cristian Loretelli, Maristella Bianconi, Riccardo Giampieri, Elena Maccaroni, Stefano Cascinu, Simona Alfonsi
Publikováno v: Journal of Translational Medicine
Journal of Translational Medicine, Vol 10, Iss 1, p 71 (2012)
e14086 Background: Other than the well-known EGFR pathway activation via the Ras-Raf-MAP-kinase, a possible role of other potential biomarkers could be relevant in determining resistance to anti-EGFR treatment, such as the protein-serine/threonine ki
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21dccd4d45f22c665e2708ca21cc4f6f
https://pubmed.ncbi.nlm.nih.gov/22490361
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10
Cox-2 Status Modulates the Activation of Hedgehog Pathway and Consequently the Expression of Stem Cell Markers in Patients with Pancreatic Ductal Adenocarcinoma
Autor: Cristian Loretelli, Stefano Cascinu, Simona Alfonsi, Matteo Santoni, Alessandra Mandolesi, Andrea Lanese, Kalliopi Andrikou, Alessandro Bittoni, Alessandro Conti, Marina Scarpelli, Chiara Pellei
Publikováno v: Annals of Oncology. 25:iv237
Aim: Inflammation is a key driver in the development of pancreatic ductal adenocarcinoma (PDAC). Cyclooxygenase-2 (COX-2) and Interleukin (IL)-6 are key modulators of inflammation and act as a potential link between chronic pancreatitis and subsequen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::472cb38a407ff34cb6eca62574c8b8ba
https://doi.org/10.1093/annonc/mdu334.83
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