In Type 2 Diabetes Mellitus Glycated Albumin Alters Macrophage Gene Expression Impairing ABCA1-Mediated Cholesterol Efflux

Autor: Marisa Passarelli, Rodrigo T. Iborra, Adriana Machado-Lima, Pietro Traldi, Annunziata Lapolla, Ubiratan Fabres Machado, Gabriela Castilho, Simona Porcu, Daniel Giannella-Neto, Camila H. Sartori, Maria Lúcia Corrêa-Giannella, Erika R. Oliveira, Marco Roverso, L. S. Okuda, R. S. Pinto, Edna Regina Nakandakare

Publikováno v: Journal of Cellular Physiology. 230:1250-1257

Advanced glycation end products (AGE) are elevated in diabetes mellitus (DM) and predict the development of atherosclerosis. AGE-albumin induces oxidative stress, which is linked to a reduction in ABCA-1 and cholesterol efflux. We characterized the g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d55a3954a99688773319325d1946c0a0
https://doi.org/10.1002/jcp.24860

Increase in urinary purines and pyrimidines in patients with methylmalonic aciduria combined with homocystinuria

Autor: L Contini, Franco Lilliu, Benedetta Era, Antonella Fais, Pietro Traldi, Simona Porcu, Marcella Corda

Publikováno v: Clinica chimica acta
411 (2010): 853–858.
info:cnr-pdr/source/autori:Porcu, S.; Corda, M.; Lilliu, F.; Contini, L.; Era, B.; Traldi, P.; Fais, A./titolo:Increase in urinary purines and pyrimidines in patients with methylmalonic aciduria combined with homocystinuria/doi:/rivista:Clinica chimica acta (Print)/anno:2010/pagina_da:853/pagina_a:858/intervallo_pagine:853–858/volume:411

Background Methylmalonic aciduria combined with homocystinuria (MMA–HC) is the biochemical trait of a metabolic disorder resulting from impaired conversion of dietary cobalamin (cbl, or vitamin B12) to its two metabolically active forms. Effects on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa7a84d86bb5e3acfe7ca26ba32661c
https://doi.org/10.1016/j.cca.2010.02.072

Glycated human serum albumin isolated from poorly controlled diabetic patients impairs cholesterol efflux from macrophages: An investigation by mass spectrometry

Autor: Annunziata Lapolla, Marco Roverso, Maria Lúcia Corrêa-Giannella, Edna Regina Nakandakare, Simona Porcu, Pietro Traldi, Gabriela Castilho, Marisa Passarelli, Adriana Machado-Lima, Camila H. Sartori

Publikováno v: European journal of mass spectrometry 21 (2015): 233–244. doi:10.1255/ejms.1322
info:cnr-pdr/source/autori:Castilho G.; Sartori C.H.; Machado-Lima A.; Nakandakare E.R.; Correa-Giannella M.L. C.; Roverso M.; Porcu S.; Lapolla A.; Traldi P.; Passarelli M./titolo:Glycated human serum albumin isolated from poorly controlled diabetic patients impairs cholesterol efflux from macrophages: an investigation by mass spectrometry/doi:10.1255%2Fejms.1322/rivista:European journal of mass spectrometry/anno:2015/pagina_da:233/pagina_a:244/intervallo_pagine:233–244/volume:21

Advanced glycation end-products impair ABCA-1-mediated cholesterol efflux by eliciting inflammation, the generation of reactive oxygen species and endoplasmatic reticulum (ER) stress. The glycation level of human serum albumin (HSA) from type 1 and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bffc3b8117c2234ba64d650df8bb05a
http://hdl.handle.net/11577/3193937

Abstract 460: Characterization of Glycated Albumin Isolated From Poorly Controlled Diabetic Patients and Its Role in Macrophage Cholesterol Efflux

Autor: Edna Regina Nakandakare, Simona Porcu, Adriana Machado-Lima, Annunziata Lapolla, Maria Lúcia Corrêa-Giannella, Marco Roverso, Marisa Passarelli, Gabriela Castilho, Pietro Traldi, Rodrigo T. Iborra, Erika R. Oliveira

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 34

Advanced glycation end products (AGE) are elevated in diabetes mellitus (DM) and predict the development of atherosclerosis. In vitro produced AGE-albumin induces oxidative stress that is linked to the reduction in ABCA-1 levels and cholesterol efflu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a816a0a0558f393d1e0dafaf67e04d1
https://doi.org/10.1161/atvb.34.suppl_1.460

A preliminary investigation on placenta protein profile reveals only modest changes in well controlled gestational diabetes mellitus

Autor: Annunziata Lapolla, G. Bogana, Pietro Traldi, Simona Porcu, Monica Carrozzini, Marco Roverso, Giovanni Battista Nardelli, Gernot Desoye, Chiara Cosma

Publikováno v: European journal of mass spectrometry (Chichester, England). 19(3)

Gestational diabetes mellitus (GDM) is associated with a wide range of tissue-specific changes depending on the quality of glycemic control of the mothers. Here we tested the hypothesis that GDM is associated with alterations in the human term placen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bb6b90ec85e208d82cd4ae41537209
https://pubmed.ncbi.nlm.nih.gov/24308201