Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Simona, Pellecchia"'
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Most primary Triple Negative Breast Cancers (TNBCs) show amplification of the Epidermal Growth Factor Receptor (EGFR) gene, leading to increased protein expression. However, unlike other EGFR-driven cancers, targeting this recepto
Externí odkaz:
https://doaj.org/article/036f678330144a45b4e6b9e53bef263c
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Intra-tumour heterogeneity (ITH) presents a significant obstacle in formulating effective treatment strategies in clinical practice. Single-cell RNA sequencing (scRNA-seq) has evolved as a powerful instrument for probing ITH at th
Externí odkaz:
https://doaj.org/article/5619108741b24d43999d6024ad171e4a
Autor:
Marco De Martino, Simona Pellecchia, Francesco Esposito, Federica Liotti, Sara Carmela Credendino, Nella Prevete, Myriam Decaussin-Petrucci, Paolo Chieffi, Gabriella De Vita, Rosa Marina Melillo, Alfredo Fusco, Pierlorenzo Pallante
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Thyroid cancer is the most prevalent endocrine malignancy and comprises a wide range of lesions subdivided into differentiated (DTC) and undifferentiated thyroid cancer (UTC), mainly represented by the anaplastic thyroid carcinoma (ATC). Thi
Externí odkaz:
https://doaj.org/article/14328b9a03ed4d13b0d1dc8260b2cacb
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/4a96212e5421441abb5bc6f8619f2e5d
Although many primary triple negative breast cancers (TNBCs) have enhanced expression of epidermal growth factor receptor (EGFR), EGFR-targeted therapies have shown only variable and unpredictable clinical responses in TNBCs. Here we integrate cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c3697aee8fc1adfc5a1bd286c7dfef8
https://doi.org/10.1101/2023.04.04.535588
https://doi.org/10.1101/2023.04.04.535588
Publikováno v:
NAR Genomics and Bioinformatics. 5
Although an essential step, the functional annotation of cells often proves particularly challenging in the analysis of single-cell transcriptional data. Several methods have been developed to accomplish this task. However, in most cases, these rely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f326cfe4fc77a781cc7c78849168e0
https://doi.org/10.1093/nargab/lqad024
https://doi.org/10.1093/nargab/lqad024
Autor:
Marco De Martino, Simona Pellecchia, Francesco Esposito, Nadia Tosti, Cristina Quintavalle, Serenella Eppenberger-Castori, Vincenza Carafa, Alberto Righi, Paolo Chieffi, Alfredo Fusco, Luigi Maria Terracciano, Pierlorenzo Pallante
Publikováno v:
Cell Cycle
Neuroendocrine tumors (NETs) are neoplasms derived from neuroendocrine cells. One of their main features is to often remain asymptomatic and clinically undetectable. High Mobility Group A (HMGA) proteins belong to a family of non-histone chromatinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c8da1f900a3c80552e77cca7468616
http://hdl.handle.net/11591/476968
http://hdl.handle.net/11591/476968
Autor:
Paula Mussnich, Serena Saggio, Daniela D'Angelo, Filippo Fraggetta, Alfredo Fusco, Domenico Solari, Paolo Cappabianca, Romina Sepe, Maddalena Raia, Sara Petrosino, Luigi Del Vecchio, Simona Pellecchia
Publikováno v:
Journal of Molecular Medicine. 97:1019-1032
Long non-coding RNAs (lncRNAs) are emerging as fundamental players in cancer biology. Indeed, they are deregulated in several neoplasias and have been associated with cancer progression, tumor recurrence, and resistance to treatment, thus representin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdca1b9df80ddbfb39faecb57b09898
https://doi.org/10.1007/s00109-019-01789-7
https://doi.org/10.1007/s00109-019-01789-7
Publikováno v:
Translational Cancer Research. 8:S211-S215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa504242f70776b0ee1729e000e76aaa
https://doi.org/10.21037/tcr.2019.03.10
https://doi.org/10.21037/tcr.2019.03.10
Autor:
Pierlorenzo Pallante, Marco De Martino, Cristina Quintavalle, Alfredo Fusco, Simona Pellecchia, Francesco Esposito
Publikováno v:
Cell Cycle
Glioblastoma (GBM) is the most aggressive and lethal neoplasia of the central nervous system in adults. Based on the molecular signature genes, GBM has been classified in proneural, neural, mesenchymal and classical subtypes. The Metallophosphoestera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0271066f17a98db86740bdd10dbbf2d4
https://europepmc.org/articles/PMC8078659/
https://europepmc.org/articles/PMC8078659/