Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Simona, Paladino"'
Autor:
Stéphanie Lebreton, Simona Paladino, Mickaël Lelek, Marc Tramier, Christophe Zimmer, Chiara Zurzolo
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
The spatiotemporal compartmentalization of membrane-associated glycosylphosphatidylinositol-anchored proteins (GPI-APs) on the cell surface regulates their biological activities. These GPI-APs occupy distinct cellular functions such as enzymes, recep
Externí odkaz:
https://doaj.org/article/9fa0b161e643413bbf6e4506620c1af9
Autor:
Laura De Rosa, Dominga Fasano, Lucrezia Zerillo, Valeria Valente, Antonella Izzo, Nunzia Mollo, Giuseppina Amodio, Elena Polishchuk, Roman Polishchuk, Mariarosa Anna Beatrice Melone, Chiara Criscuolo, Anna Conti, Lucio Nitsch, Paolo Remondelli, Giovanna Maria Pierantoni, Simona Paladino
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Endosomal trafficking is essential for cellular homeostasis. At the crossroads of distinct intracellular pathways, the endolysosomal system is crucial to maintain critical functions and adapt to the environment. Alterations of endosomal compartments
Externí odkaz:
https://doaj.org/article/bb7c01ded3ef4671ac7aa624d3cba628
Autor:
Federica Liotti, Narender Kumar, Nella Prevete, Maria Marotta, Daniela Sorriento, Caterina Ieranò, Andrea Ronchi, Federica Zito Marino, Sonia Moretti, Renato Colella, Efiso Puxeddu, Simona Paladino, Yoshihito Kano, Michael Ohh, Stefania Scala, Rosa Marina Melillo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Abstract Background The programmed cell death-1 (PD-1) receptor and its ligands PD-L1 and PD-L2 are immune checkpoints that suppress anti-cancer immunity. Typically, cancer cells express the PD-Ls that bind PD-1 on immune cells, inhibiting their acti
Externí odkaz:
https://doaj.org/article/2f4f62c217e14f8f9af474f8e752ef34
Autor:
Luigi Marino, Bruno Charlier, Valentina Giudice, Paolo Remondelli, Simona Paladino, Rosa Vitolo, Fabrizio Dal Piaz, Barbara Izzo, Pio Zeppa, Viviana Izzo, Amelia Filippelli, Carmine Selleri
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 356-360 (2020)
Externí odkaz:
https://doaj.org/article/b9c5fbbb22784fa28441231d92ac56a5
Autor:
Nunzia Mollo, Miriam Aurilia, Roberta Scognamiglio, Lucrezia Zerillo, Rita Cicatiello, Ferdinando Bonfiglio, Pasqualina Pagano, Simona Paladino, Anna Conti, Lucio Nitsch, Antonella Izzo
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Down syndrome is a neurodevelopmental disorder frequently characterized by other developmental defects, such as congenital heart disease. Analysis of gene expression profiles of hearts from trisomic fetuses have shown upregulation of extracellular ma
Externí odkaz:
https://doaj.org/article/6f3f852b01ea4178816acde55f113e27
Autor:
Vincenzo Vestuto, Giuseppina Amodio, Giacomo Pepe, Manuela Giovanna Basilicata, Raffaella Belvedere, Enza Napolitano, Daniela Guarnieri, Valentina Pagliara, Simona Paladino, Manuela Rodriquez, Alessia Bertamino, Pietro Campiglia, Paolo Remondelli, Ornella Moltedo
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 2009 (2022)
Parkinson’s disease (PD) represents one of the most common neurodegenerative disorders, characterized by a dopamine (DA) deficiency in striatal synapses and misfolded toxic α-synuclein aggregates with concomitant cytotoxicity. In this regard, the
Externí odkaz:
https://doaj.org/article/8273afd6b2414f98a31c9f0baef5e4d5
Autor:
Nunzia Mollo, Maria Nitti, Lucrezia Zerillo, Deriggio Faicchia, Teresa Micillo, Rossella Accarino, Agnese Secondo, Tiziana Petrozziello, Gaetano Calì, Rita Cicatiello, Ferdinando Bonfiglio, Viviana Sarnataro, Rita Genesio, Antonella Izzo, Paolo Pinton, Giuseppe Matarese, Simona Paladino, Anna Conti, Lucio Nitsch
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/e7a461318e36402eb25ecba9b05896ba
Autor:
Valeria De Pasquale, Patrizia Sarogni, Valeria Pistorio, Giuliana Cerulo, Simona Paladino, Luigi Michele Pavone
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 8-16 (2018)
Mucopolysaccharidoses (MPSs) are inherited metabolic diseases caused by the deficiency of lysosomal enzymes needed to catabolize glycosaminoglycans (GAGs). Four therapeutic options are currently considered: enzyme replacement therapy, substrate reduc
Externí odkaz:
https://doaj.org/article/0a95da95c6a04cbc8f1dec282116e797
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 5, Pp 1951-1976 (2018)
A general hallmark of neurological diseases is the loss of redox homeostasis that triggers oxidative damages to biomolecules compromising neuronal function. Under physiological conditions the steady-state concentrations of reactive oxygen species (RO
Externí odkaz:
https://doaj.org/article/18d17e3817c04eada0176d2c7d2cadf4
Autor:
Antonella Izzo, Nunzia Mollo, Maria Nitti, Simona Paladino, Gaetano Calì, Rita Genesio, Ferdinando Bonfiglio, Rita Cicatiello, Maria Barbato, Viviana Sarnataro, Anna Conti, Lucio Nitsch
Publikováno v:
Molecular Medicine, Vol 24, Iss 1, Pp 1-8 (2018)
Abstract Trisomy of chromosome 21 (TS21) is the most common autosomal aneuploidy compatible with postnatal survival with a prevalence of 1 in 700 newborns. Its phenotype is highly complex with constant features, such as mental retardation, dysmorphic
Externí odkaz:
https://doaj.org/article/4ee9b0798112484caf1c2a218a487dab