Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Simona, Malaspina"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The aim of this study was to develop a convolutional neural network (CNN) for classifying positron emission tomography (PET) images of patients with and without head and neck squamous cell carcinoma (HNSCC) and other types of head and neck c
Externí odkaz:
https://doaj.org/article/9fdb55474bbd441597a19d720ae9c98b
Autor:
Jukka Kemppainen, Aki Kangasmäki, Simona Malaspina, Bernd Pape, Jarno Jalomäki, Kalevi Kairemo, Juha Kononen, Timo Joensuu
Publikováno v:
Cancers, Vol 14, Iss 24, p 6155 (2022)
Background: 177Lu-PSMA-617 is a promising theragnostic treatment for metastatic castration-resistant prostate cancer (mCRPC). However, both the optimal treatment dose and interval in mCRPC and the rate of identification of responders from non-respond
Externí odkaz:
https://doaj.org/article/14ce7a0f9ef5475790a736d30cf26978
Publikováno v:
Metabolites, Vol 12, Iss 4, p 321 (2022)
Evaluating in vivo the metabolic rates of the human liver has been a challenge due to its unique perfusion system. Positron emission tomography (PET) represents the current gold standard for assessing non-invasively tissue metabolic rates in vivo. He
Externí odkaz:
https://doaj.org/article/2e05efbc7a8345cea88d5bfd3114edd0
Autor:
Simona Malaspina, Otto Ettala, Tuula Tolvanen, Johan Rajander, Olli Eskola, Peter. J. Boström, Jukka Kemppainen
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 50:613-621
Purpose Short-term androgen deprivation therapy (ADT) is known to increase heterogeneously prostate-specific membrane antigen (PSMA) expression. This phenomenon might indicate the potential of cancer lesions to respond to ADT. In this prospective stu
Autor:
Sarita Murtojärvi, Simona Malaspina, Ilpo Kinnunen, Terhi Tuokkola, Miikka-Juhani Honka, Virva Saunavaara, Tuula Tolvanen, Aleksi Schrey, Jukka Kemppainen
Publikováno v:
Contrast Media & Molecular Imaging. 2022:1-13
Purpose. In head and neck squamous cell carcinoma (HNSCC), the early diagnosis and efficient detection of recurrences and/or residual tumor after treatment play a very important role in patient’s prognosis. Positron emission tomography (PET) using
Autor:
Anna Kuisma, Simona Malaspina, Mika Scheinin, Ernst J. Postema, Kalle Mattila, Kari K. Kalliokoski, Peter J. Boström, Otto Ettala, Matthew P. Miller, Heikki Minn, Vesa Oikonen
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose This phase 1 open-label study evaluated the uptake kinetics of a novel theranostic PET radiopharmaceutical, 18F-rhPSMA-7.3, to optimise its use for imaging of prostate cancer. Methods Nine men, three with high-risk localised prostate cancer,
Autor:
Simona, Malaspina, Otto, Ettala, Tuula, Tolvanen, Johan, Rajander, Olli, Eskola, Peter J, Boström, Jukka, Kemppainen
Publikováno v:
European journal of nuclear medicine and molecular imaging. 50(2)
Short-term androgen deprivation therapy (ADT) is known to increase heterogeneously prostate-specific membrane antigen (PSMA) expression. This phenomenon might indicate the potential of cancer lesions to respond to ADT. In this prospective study, we e
Autor:
Sarita, Murtojärvi, Simona, Malaspina, Ilpo, Kinnunen, Terhi, Tuokkola, Miikka-Juhani, Honka, Virva, Saunavaara, Tuula, Tolvanen, Aleksi, Schrey, Jukka, Kemppainen
Publikováno v:
Contrast mediamolecular imaging. 2022
In head and neck squamous cell carcinoma (HNSCC), the early diagnosis and efficient detection of recurrences and/or residual tumor after treatment play a very important role in patient's prognosis. Positron emission tomography (PET) using 2-deoxy-2-T
Autor:
Samuli Arvola, Marko Seppänen, Simona Malaspina, Sorjo Mätzke, Juho Raiko, Kirsi L. Timonen, Otto Ettala, Ivan Jambor, Mikael Anttinen, Anna Kuisma, Eliisa Löyttyniemi, Peter J. Boström, Antti Sohlberg, Tommi Noponen
Objective The aim of this study was to compare reprojected bone SPECT/CT (RBS) against planar bone scintigraphy (BS) in the detection of bone metastases in breast and prostate cancer patients. Methods Twenty-six breast and 105 prostate cancer patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c29e66670f9afb4ade498c973fb1c1
http://hdl.handle.net/10138/344265
http://hdl.handle.net/10138/344265
Autor:
Simona Malaspina, Matthew P. Miller, Salla Lahdenpohja, Kari K. Kalliokoski, Anna Kuisma, Tuula Tolvanen, Mika Scheinin, Ernst J. Postema
Publikováno v:
Journal of Nuclear Medicine. 62:679-684
This first-in-human study investigated the safety, biodistribution and radiation dosimetry of the novel 18F-labeled radiohybrid prostate-specific membrane antigen (rhPSMA) positron emission tomography (PET) imaging agent, 18F-rhPSMA-7.3. Methods: Six