Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Simon von Kroge"'
Autor:
Laura J. Brylka, Assil-Ramin Alimy, Miriam E. A. Tschaffon-Müller, Shan Jiang, Tobias Malte Ballhause, Anke Baranowsky, Simon von Kroge, Julian Delsmann, Eva Pawlus, Kian Eghbalian, Klaus Püschel, Astrid Schoppa, Melanie Haffner-Luntzer, David J. Beech, Frank Timo Beil, Michael Amling, Johannes Keller, Anita Ignatius, Timur A. Yorgan, Tim Rolvien, Thorsten Schinke
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Piezo proteins are mechanically activated ion channels, which are required for mechanosensing functions in a variety of cell types. While we and others have previously demonstrated that the expression of Piezo1 in osteoblast lineage cells is
Externí odkaz:
https://doaj.org/article/a1586c2aa5be4762bf608a21489eff44
Autor:
Nele Vollersen, Wenbo Zhao, Tim Rolvien, Fabiola Lange, Felix Nikolai Schmidt, Stephan Sonntag, Doron Shmerling, Simon von Kroge, Kilian Elia Stockhausen, Ahmed Sharaf, Michaela Schweizer, Meliha Karsak, Björn Busse, Ernesto Bockamp, Oliver Semler, Michael Amling, Ralf Oheim, Thorsten Schinke, Timur Alexander Yorgan
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract The recent identification of homozygous WNT1 mutations in individuals with osteogenesis imperfecta type XV (OI-XV) has suggested that WNT1 is a key ligand promoting the differentiation and function of bone-forming osteoblasts. Although such
Externí odkaz:
https://doaj.org/article/dec15195222f43c6a21a6c77c8ffa7fd
Autor:
Cita Nottmeier, Maximilian G. Decker, Julia Luther, Simon von Kroge, Bärbel Kahl-Nieke, Michael Amling, Thorsten Schinke, Julian Petersen, Till Koehne
Publikováno v:
International Journal of Oral Science, Vol 12, Iss 1, Pp 1-8 (2020)
Abstract Coffin–Lowry–Syndrome (CLS) is a X-linked mental retardation characterized by skeletal dysplasia and premature tooth loss. We and others have previously demonstrated that the ribosomal S6 kinase RSK2, mutated in CLS, is essential for bon
Externí odkaz:
https://doaj.org/article/5f7eea3ea2da47208cb6a699110d50d6
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100680- (2020)
Externí odkaz:
https://doaj.org/article/e2b7c5d54d294e508ab132f529cb54ff
Autor:
Tim Rolvien, Osman Avci, Simon von Kroge, Till Koehne, Stefan Selbert, Stephan Sonntag, Doron Shmerling, Uwe Kornak, Ralf Oheim, Michael Amling, Thorsten Schinke, Timur Alexander Yorgan
Publikováno v:
Bone Reports, Vol 12, Iss , Pp 100281- (2020)
Mutations in the gene ANO5, encoding for the transmembrane protein Anoctamin 5 (Ano5), have been identified to cause gnathodiaphyseal dysplasia (GDD) in humans, a skeletal disorder characterized by sclerosis of tubular bones, increased fracture risk
Externí odkaz:
https://doaj.org/article/0680a50d4a4a43ddb73b5ae33b998844
Autor:
Leon-Gordian Koepke, Simon von Kroge, Annika Heuer, Anna Lena Kammal, Benjamin Ondruschka, Tim Rolvien, Lennart Viezens
Publikováno v:
Calcified Tissue International. 112:563-572
The odontoid process (dens) of the second cervical vertebra (axis) is prone to fracture. While the importance of its skeletal integrity has been previously noted, representative three-dimensional microarchitecture analyses in humans are not available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06b271f598641ace2c818280b8ffeb7d
https://doi.org/10.1007/s00223-023-01070-7
https://doi.org/10.1007/s00223-023-01070-7
Autor:
Kristin Zimmerman, Xiaochen Liu, Simon von Kroge, Paul Stabach, Ethan R. Lester, Emily Y. Chu, Shivani Srivastava, Martha J. Somerman, Steven M. Tommasini, Björn Busse, Thorsten Schinke, Thomas O. Carpenter, Ralf Oheim, Demetrios T. Braddock
Publikováno v:
Journal of Bone and Mineral Research. 37:1733-1749
Biallelic ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) deficiency induces vascular/soft tissue calcifications in generalized arterial calcification of infancy (GACI), and low bone mass with phosphate-wasting rickets in GACI survivors (a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314e95b8fd71f70c02b69948a42477c8
https://doi.org/10.1002/jbmr.4640
https://doi.org/10.1002/jbmr.4640
Autor:
Simon von Kroge, Julian Stürznickel, Ulrich Bechler, Kilian Elia Stockhausen, Julian Eissele, Jan Hubert, Michael Amling, Frank Timo Beil, Björn Busse, Tim Rolvien
Publikováno v:
Acta Biomaterialia. 141:233-243
Skeletal adaptation is substantially influenced by mechanical loads. Osteocytes and their lacuno-canalicular network have been identified as a key player in load sensation and bone quality regulation. In the femoral neck, one of the most common fract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d7f56026d99ac8c59fc5292dd1c0c3
https://doi.org/10.1016/j.actbio.2022.01.002
https://doi.org/10.1016/j.actbio.2022.01.002
Autor:
Thorsten Gehrke, Michael Amling, Sebastian Butscheidt, Klaus Püschel, Simon von Kroge, Julian Stürznickel, Tim Rolvien, Michael Hahn, Frank Timo Beil
Publikováno v:
Journal of Bone and Joint Surgery. 103:1996-2005
Background Impacted bone-grafting with morselized allograft chips is commonly used to reconstruct acetabular bone defects in revision total hip arthroplasty (THA). While the overall clinical outcome of this procedure is described to be excellent, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af1ef9189376084db589ab7b8fdd835
https://doi.org/10.2106/jbjs.20.01943
https://doi.org/10.2106/jbjs.20.01943
Autor:
Eva Maria Wölfel, Simon von Kroge, Levi Matthies, Till Koehne, Karin Petz, Thomas Beikler, Carmen Ulrike Schmid-Herrmann, Bärbel Kahl-Nieke, Konstantinos Tsiakas, René Santer, Nicole Maria Muschol, Jochen Herrmann, Björn Busse, Michael Amling, Tim Rolvien, Nico Maximilian Jandl, Florian Barvencik
Publikováno v:
Calcified tissue international.
Hypophosphatasia (HPP) is an inherited, systemic disorder, caused by loss-of-function variants of the ALPL gene encoding the enzyme tissue non-specific alkaline phosphatase (TNSALP). HPP is characterized by low serum TNSALP concentrations associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e845568855b4b8fdefeb64ff5acdd7
https://pubmed.ncbi.nlm.nih.gov/36414794
https://pubmed.ncbi.nlm.nih.gov/36414794