Zobrazeno 1 - 10
of 390
pro vyhledávání: '"Simon Young"'
Autor:
Chi T. Viet, Kesava R. Asam, Gary Yu, Emma C. Dyer, Sara Kochanny, Carissa M. Thomas, Nicholas F. Callahan, Anthony B. Morlandt, Allen C. Cheng, Ashish A. Patel, Dylan F. Roden, Simon Young, James Melville, Jonathan Shum, Paul C. Walker, Khanh K. Nguyen, Stephanie N. Kidd, Steve C. Lee, Gretchen S. Folk, Dan T. Viet, Anupama Grandhi, Jeremy Deisch, Yi Ye, Fatemeh Momen-Heravi, Alexander T. Pearson, Bradley E. Aouizerat
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Oral squamous cell carcinoma (OSCC) biomarker studies rarely employ multi-omic biomarker strategies and pertinent clinicopathologic characteristics to predict mortality. In this study we determine for the first time a combined epigenetic, ge
Externí odkaz:
https://doaj.org/article/63aef0703ac64ce0b658b39a70199d81
Autor:
Simon Young, Andrew Sikora, Sofia Cortes, Ratna Veeramachaneni, Fabio Henrique Brasil da Costa, Rohan Bhavane, Sarah L Latka, Andrew Badachhape, Renuka TR Menon, Prajwal Bhandari, Ketankumar B Ghaghada, Ananth V Annapragada
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/dbc65667cb8a4e7d8530ca539f6894c4
Autor:
Minh Phuong Dong, Neeraja Dharmaraj, Estela Kaminagakura, Jianfei Xue, David G. Leach, Jeffrey D. Hartgerink, Michael Zhang, Hana-Joy Hanks, Yi Ye, Bradley E. Aouizerat, Kyle Vining, Carissa M. Thomas, Sinisa Dovat, Simon Young, Chi T. Viet
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 920 (2024)
Oral squamous cell carcinoma (OSCC) presents significant treatment challenges due to its poor survival and intense pain at the primary cancer site. Cancer pain is debilitating, contributes to diminished quality of life, and causes opioid tolerance. T
Externí odkaz:
https://doaj.org/article/6e08a52ce46a4c4ebfc4aafaca817580
Autor:
Neelam Ahuja, Kamal Awad, Su Yang, He Dong, Antonios Mikos, Pranesh Aswath, Simon Young, Marco Brotto, Venu Varanasi
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 189 (2024)
Healing in compromised and complicated bone defects is often prolonged and delayed due to the lack of bioactivity of the fixation device, secondary infections, and associated oxidative stress. Here, we propose amorphous silicon oxynitride (SiONx) as
Externí odkaz:
https://doaj.org/article/5f621ba688d24830961e0d1fa0b2ec1e
Autor:
Kamal Awad, Neelam Ahuja, Ahmed S. Yacoub, Leticia Brotto, Simon Young, Antonios Mikos, Pranesh Aswath, Venu Varanasi
Publikováno v:
Frontiers in Aging, Vol 4 (2023)
In this review, we explore the application of novel biomaterial-based therapies specifically targeted towards craniofacial bone defects. The repair and regeneration of critical sized bone defects in the craniofacial region requires the use of bioacti
Externí odkaz:
https://doaj.org/article/add35b0a75ff4f588bd77cd214bc661b
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Self-assembling peptides are a type of biomaterial rapidly emerging in the fields of biomedicine and material sciences due to their promise in biocompatibility and effectiveness at controlled release. These self-assembling peptides can form diverse n
Externí odkaz:
https://doaj.org/article/f3e5a7da7bf0451f8d985757625f13a2
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0288039 (2023)
IntroductionThe Amyloid/Tau/Neurodegeneration (ATN) framework was proposed to identify the preclinical biological state of Alzheimer's disease (AD). We investigated whether ATN phenotype can be predicted using routinely collected research cohort data
Externí odkaz:
https://doaj.org/article/c0028ac315cf439f88dd941aac8db92a
Autor:
Sarmi Sri, Adam Greenstein, Alessandra Granata, Alex Collcutt, Angela C C Jochems, Barry W McColl, Blanca Díaz Castro, Caleb Webber, Carmen Arteaga Reyes, Catherine Hall, Catherine B Lawrence, Cheryl Hawkes, Chrysia-Maria Pegasiou-Davies, Claire Gibson, Colin L Crawford, Colin Smith, Denis Vivien, Fiona H McLean, Frances Wiseman, Gaia Brezzo, Giovanna Lalli, Harry A T Pritchard, Hugh S Markus, Isabel Bravo-Ferrer, Jade Taylor, James Leiper, Jason Berwick, Jian Gan, John Gallacher, Jonathan Moss, Jozien Goense, Letitia McMullan, Lorraine Work, Lowri Evans, Michael S Stringer, MLJ Ashford, Mohamed Abulfadl, Nina Conlon, Paresh Malhotra, Philip Bath, Rebecca Canter, Rosalind Brown, Selvi Ince, Silvia Anderle, Simon Young, Sophie Quick, Stefan Szymkowiak, Steve Hill, Stuart Allan, Tao Wang, Terry Quinn, Tessa Procter, Tracy D Farr, Xiangjun Zhao, Zhiyuan Yang, Atticus H Hainsworth, Joanna M Wardlaw
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 5, Iss , Pp 100189- (2023)
Although dementia research has been dominated by Alzheimer's disease (AD), most dementia in older people is now recognised to be due to mixed pathologies, usually combining vascular and AD brain pathology. Vascular cognitive impairment (VCI), which e
Externí odkaz:
https://doaj.org/article/9ffe49ccbd5b476183d732a9dab4e59d
Autor:
Chi T. Viet, Xinyu Zhang, Ke Xu, Gary Yu, Kesava Asam, Carissa M. Thomas, Nicholas F. Callahan, Coleen Doan, Paul C. Walker, Khanh Nguyen, Stephanie C. Kidd, Steve C. Lee, Anupama Grandhi, Clint T. Allen, Simon Young, James C. Melville, Jonathan W. Shum, Dan T. Viet, Alan S. Herford, Dylan F. Roden, Manuel L. Gonzalez, Jiang F. Zhong, Bradley E. Aouizerat
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-10 (2021)
Abstract Background Oral squamous cell carcinoma (OSCC) has poor survival rates. There is a pressing need to develop more precise risk assessment methods to tailor clinical treatment. Epigenome-wide association studies in OSCC have not produced a via
Externí odkaz:
https://doaj.org/article/260f7bc1d90040bebd27e0254089dfb3
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Nomograms are currently used in predicting individualized outcomes in clinical oncology of several cancers. However, nomograms for evaluating occult nodal metastasis of patients with squamous cell carcinoma of lateral tongue (SCCL
Externí odkaz:
https://doaj.org/article/ac44ca76a1884f04a9b299f9e5dd8a70