Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Simon Yona"'
Autor:
Gourab Dey, Reut Sinai‐Turyansky, Evalyn Yakobovich, Emmanuelle Merquiol, Jure Loboda, Nikhila Sridharan, Yael Houri‐Haddad, David Polak, Simon Yona, Dusan Turk, Ori Wald, Galia Blum
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Cathepsin‐K (CTSK) is an osteoclast‐secreted cysteine protease that efficiently cleaves extracellular matrices and promotes bone homeostasis and remodeling, making it an excellent therapeutic target. Detection of CTSK activity in complex
Externí odkaz:
https://doaj.org/article/55a9f6f7610d46bd811724ab06c48696
Autor:
Lei Xia, Anastasia Komissarova, Arielle Jacover, Yehuda Shovman, Sebastian Arcila-Barrera, Sharona Tornovsky-Babeay, Milsee Mol Jaya Prakashan, Abdelmajeed Nasereddin, Inbar Plaschkes, Yuval Nevo, Idit Shiff, Oshri Yosefov-Levi, Tamara Izhiman, Eleonora Medvedev, Elad Eilon, Asaf Wilensky, Simon Yona, Oren Parnas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Genetic engineering of immune cells has opened new avenues for improving their functionality but it remains a challenge to pinpoint which genes or combination of genes are the most beneficial to target. Here, we conduct High Multiplicity of
Externí odkaz:
https://doaj.org/article/b0e9908d96c24b16a84a01bc03b9af6b
Autor:
Ekaterini Maria Lyras, Karin Zimmermann, Lisa Katharina Wagner, Dorothea Dörr, Christoph SN Klose, Cornelius Fischer, Steffen Jung, Simon Yona, Avi-Hai Hovav, Werner Stenzel, Steffen Dommerich, Thomas Conrad, Achim Leutz, Alexander Mildner
Publikováno v:
eLife, Vol 11 (2022)
The tongue is a unique muscular organ situated in the oral cavity where it is involved in taste sensation, mastication, and articulation. As a barrier organ, which is constantly exposed to environmental pathogens, the tongue is expected to host an im
Externí odkaz:
https://doaj.org/article/bdec5d45da9b4982bda0ef6698f9511b
Autor:
Amit A. Patel, Simon Yona
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Blood monocytes develop in the bone marrow before being released into the peripheral circulation. The circulating monocyte pool is composed of multiple subsets, each with specialized functions. These cells are recruited to repopulate resident monocyt
Externí odkaz:
https://doaj.org/article/45aa2dfcc3c94d79b0aa4733a5a60e7e
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The phagosome microenvironment maintains enzyme activity and function. Here we compared the phagosomal pH of human neutrophils, monocytes, dendritic cells (DC), and monocyte-derived cells. An unexpected observation was the striking difference in phag
Externí odkaz:
https://doaj.org/article/07d694d74ac24902beca50a34a73a080
Autor:
Noam Cohen, Raanan Margalit, Meirav Pevsner-Fischer, Simon Yona, Steffen Jung, Lea Eisenbach, Irun R Cohen
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39193 (2012)
Mice are exceedingly sensitive to intra-peritoneal (IP) challenge with some virulent pneumococci (LD50 = 1 bacterium). To investigate how peripheral contact with bacterial capsular polysaccharide (PS) antigen can induce resistance, we pulsed bone mar
Externí odkaz:
https://doaj.org/article/17d44963cdd944b1a44f0416d69881a0
Autor:
Wouter ten Voorde, Robert Rissmann, Michelle Osse, Manon A. A. Jansen, G. Feiss, Edwin Florencia, Mascha Schoonakker, Floris C. van Hindevoort, Matthijs Moerland, Erik Lubberts, Pieter W Hameeteman, Thomas P. Buters, Jeffrey Damman, Amit Patel, Iris M. E. Jansen, Marieke L. de Kam, Jacobus Burggraaf, Simon Yona, Derek W. Gilroy, Hendrika W. Grievink
Publikováno v:
British Journal of Clinical Pharmacology, 88(2), 680-690. Wiley-Blackwell Publishing Ltd
British Journal of Clinical Pharmacology, 88(2), 680-690. WILEY
British Journal of Clinical Pharmacology, 88(2), 680-690. WILEY
Aims: Whereas intravenous administration of Toll-like receptor 4 ligand lipopolysaccharide (LPS) to human volunteers is frequently used in clinical pharmacology studies, systemic use of LPS has practical limitations. We aimed to characterize the intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb4f5bb07a1c0316ac2a4f7f02dc25a
http://www.scopus.com/inward/record.url?scp=85113808796&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85113808796&partnerID=8YFLogxK
INTRODUCTION: Monocyte distribution width (MDW), a parameter generated alongside full blood counts (FBC) in new-generation haematology analysers, has been proposed as a diagnostic test for severe infection/sepsis. It represents the standard deviation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48dc8b5bf55fd00d60caf0eebcbdcf5
Autor:
Asaf Wilensky, A Laviv, Gabriel Mizraji, Oded Heyman, Y Horev, Lior Shapira, H Sharawi, Avi-Hai Hovav, Simon Yona
Publikováno v:
Journal of Dental Research. 100:1330-1336
As the most potent cells activating and polarizing naive T cells, dendritic cells (DCs) are of major importance in the induction of immunity and tolerance. DCs are a heterogeneous population of antigen-presenting cells that are widely distributed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b16cd90bcc04ee3fc07a88f19c2759
https://doi.org/10.1177/00220345211004864
https://doi.org/10.1177/00220345211004864