Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Simon Willis"'
Autor:
Diana Zatreanu, Helen M. R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, Diego Grande, Vera Grinkevich, Robert A. Heald, Sophie Langdon, Jayesh Majithiya, Claire McWhirter, Niall M. B. Martin, Shaun Moore, Joana Neves, Eeson Rajendra, Marco Ranzani, Theresia Schaedler, Martin Stockley, Kimberley Wiggins, Rachel Brough, Sandhya Sridhar, Aditi Gulati, Nan Shao, Luned M. Badder, Daniela Novo, Eleanor G. Knight, Rebecca Marlow, Syed Haider, Elsa Callen, Graeme Hewitt, Joost Schimmel, Remko Prevo, Christina Alli, Amanda Ferdinand, Cameron Bell, Peter Blencowe, Chris Bot, Mathew Calder, Mark Charles, Jayne Curry, Tennyson Ekwuru, Katherine Ewings, Wojciech Krajewski, Ellen MacDonald, Hollie McCarron, Leon Pang, Chris Pedder, Laurent Rigoreau, Martin Swarbrick, Ed Wheatley, Simon Willis, Ai Ching Wong, Andre Nussenzweig, Marcel Tijsterman, Andrew Tutt, Simon J. Boulton, Geoff S. Higgins, Stephen J. Pettitt, Graeme C. M. Smith, Christopher J. Lord
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Polθ has been recently identified as a therapeutic target in cancer but specific inhibitors are currently unavailable. Here, the authors identify small molecule inhibitors of Polθ’s polymerase activity which elicit BRCA1/2 synthetic lethality, en
Externí odkaz:
https://doaj.org/article/a5462d8522964b13a5f79a9e1b35250a
Autor:
Martin L. Stockley, Amanda Ferdinand, Giovanni Benedetti, Peter Blencowe, Susan M. Boyd, Mat Calder, Mark D. Charles, Lucy V. Edwardes, Tennyson Ekwuru, Harry Finch, Alessandro Galbiati, Lerin Geo, Diego Grande, Vera Grinkevich, Nicholas D. Holliday, Wojciech W. Krajewski, Ellen MacDonald, Jayesh B. Majithiya, Hollie McCarron, Claire L. McWhirter, Viral Patel, Chris Pedder, Eeson Rajendra, Marco Ranzani, Laurent J. M. Rigoreau, Helen M. R. Robinson, Theresia Schaedler, Julija Sirina, Graeme C. M. Smith, Martin E. Swarbrick, Andrew P. Turnbull, Simon Willis, Robert A. Heald
Publikováno v:
Journal of Medicinal Chemistry. 65:13879-13891
Human DNA polymerase theta (Polθ), which is essential for microhomology-mediated DNA double strand break repair, has been proposed as an attractive target for the treatment of BRCA deficient and other DNA repair pathway defective cancers. As previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3234589eaa7f5350d23a2af196b12e
https://doi.org/10.1021/acs.jmedchem.2c01142
https://doi.org/10.1021/acs.jmedchem.2c01142
Publikováno v:
ECS Meeting Abstracts. :1123-1123
Aluminum oxide (alumina) thin films deposited through atomic layer deposition (ALD) are of great interest in chemical barrier and corrosion protection applications. However, the stability of ALD alumina in aqueous solutions is still not fully underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20eac8fee5905223543b164b9e4dc9bd
https://doi.org/10.1149/ma2022-02311123mtgabs
https://doi.org/10.1149/ma2022-02311123mtgabs
Autor:
Chris Murdock, Ralph Whitcher, J Hunter, Tim Coldwell, Sarah Dorling, Simon Willis, P Cole, G Mott
Publikováno v:
Journal of radiological protection : official journal of the Society for Radiological Protection. 40(4)
This article reports on the research by a working group, comprising members from the Association of University Radiation Protection Officers, on the radiation safety culture in the UK higher education, research and teaching (HERT) sectors. The impetu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02390a6d3725758ff43d8631dca9cb5c
https://pubmed.ncbi.nlm.nih.gov/33105110
https://pubmed.ncbi.nlm.nih.gov/33105110
Publikováno v:
Anesthesiology Clinics. 35:247-257
Obesity has increased in incidence worldwide. Along with the increased number of obese patients, comorbid conditions are also more prevalent in this population. Obesity leads to changes in the physiology of patients along with an altered response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c2174e9e79b2c2fdb1d117197fc535
https://doi.org/10.1016/j.anclin.2017.01.010
https://doi.org/10.1016/j.anclin.2017.01.010
Publikováno v:
Deer's Treatment of Pain ISBN: 9783030122805
Radiofrequency (RF) therapy has been utilized in the management of many chronic pain conditions. The setup of the RF circuit includes a generator, a dispersive pad (often referred to as a “grounding pad”), an insulated introducer needle, and an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89f9636a85a6f390d1e9b8e0d28cbdf
https://doi.org/10.1007/978-3-030-12281-2_33
https://doi.org/10.1007/978-3-030-12281-2_33
Publikováno v:
Adaptive Sports Medicine ISBN: 9783319565668
Adaptive water sports provide an excellent resource and opportunity for athletes with a disability with varying types and levels of impairment to participate on both the recreational and competitive stage. Through modifications and adaptations, athle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad69e6782a642371ca4faa96401abd25
https://doi.org/10.1007/978-3-319-56568-2_21
https://doi.org/10.1007/978-3-319-56568-2_21
Autor:
Maunuk V. Rana, Simon Willis
Publikováno v:
Challenging Cases and Complication Management in Pain Medicine ISBN: 9783319600703
Lead migration represents the most common complication observed in both trial and permanent spinal cord stimulators (SCS). Depending on the level of migration or lead translocation, patients may demonstrate predominantly sensory characteristics, rare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89057ac13d75fbb85eca3ab9aedb92cd
https://doi.org/10.1007/978-3-319-60072-7_51
https://doi.org/10.1007/978-3-319-60072-7_51
Autor:
Simon Willis, Reid A. Waldman
Publikováno v:
Physical Medicine and Rehabilitation Research. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d439dd253912c702e2ce8b08ee078917
https://doi.org/10.15761/pmrr.1000104
https://doi.org/10.15761/pmrr.1000104
Autor:
Simon Willis
Publikováno v:
Journal of Money Laundering Control. 3:45-49
In the author's last article (JMLC, Vol. 2, No. 3) reference was made to ‘thefts dressed as non‐performing loans’ and the catastrophic risks run by individual financial institutions as well as whole markets and economies that compromise with cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5dd5958e6a0cb07893005bfef05a3d0
https://doi.org/10.1108/eb027210
https://doi.org/10.1108/eb027210