Výsledky vyhledávání - "Simon Welner"

Akademický článek

Reduced Virus Load in Lungs of Pigs Challenged with Porcine Reproductive and Respiratory Syndrome Virus after Vaccination with Virus Replicon Particles Encoding Conserved PRRSV Cytotoxic T-Cell Epitopes

Autor: Simon Welner, Nicolas Ruggli, Matthias Liniger, Artur Summerfield, Lars Erik Larsen, Gregers Jungersen

Publikováno v: Vaccines, Vol 9, Iss 3, p 208 (2021)

Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe respiratory distress and reproductive failure in swine. Modified live virus (MLV) vaccines provide the highest degree of protection and are most often the preferred choice. Whi

Externí odkaz: https://doaj.org/article/0a4b3e46ac7f4386955421839d1b0d7e

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Prediction and in vitro verification of potential CTL epitopes conserved among PRRSV-2 strains

Autor: Morten Nielsen, Simon Welner, Gregers Jungersen, Søren Buus, Michael R. Rasmussen, Lars Erik Larsen

Publikováno v: Welner, S, Nielsen, M, Rasmussen, M, Buus, S, Jungersen, G & Larsen, L E 2017, ' Prediction and in vitro verification of potential CTL epitopes conserved among PRRSV-2 strains ', Immunogenetics, vol. 69, no. 10, pp. 689-702 . https://doi.org/10.1007/s00251-017-1004-8
Immunogenetics

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is the causative agent of one of the most important porcine diseases with a high impact on animal health, welfare, and production economy. PRRSV exhibits a multitude of immunoevasive strateg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9692e6b6e12ba87dceb68968e412f92
https://doi.org/10.1007/s00251-017-1004-8

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Identification and mapping of a linear epitope of centromere protein F using monoclonal antibodies

Autor: Nicole Hartwig Trier, Paul R. Hansen, Simon Welner, Gunnar Houen

Publikováno v: Journal of Peptide Science. 19:95-101

Autoantibodies against centromere protein -F have been reported to be associated with various types of cancer with poor prognosis. The characterization of these autoantibody specificities is important in both diagnostics and basic research. In this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::83651b482a346e91b991c136ec8affe7
https://doi.org/10.1002/psc.2478

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Tracking the elusive cytotoxic T cell response in pigs

Autor: Gregers Jungersen, Morten Nielsen, Nana Haahr Overgaard, Thomas Mørch Frøsig, Maria Rathmann Sørensen, Simon Welner, Mikael Lenz Strube, Lasse Eggers Pedersen, Ole Lund, Golde, William T., Søren Buus

Publikováno v: Jungersen, G, Nielsen, M, Overgaard, N H, Frøsig, T M, Sørensen, M R, Welner, S, Strube, M L, Pedersen, L E, Lund, O, Golde, W T & Buus, S 2016, ' Tracking the elusive cytotoxic T cell response in pigs ' 11th International Veterinary Immunology Symposium, Gold Coast, Australia, 16/08/2016-19/08/2016, .
Technical University of Denmark Orbit

Quantitative and qualitative assessment of antigen-specific cytotoxic T cell (CTL) responses in pigs is not a straightforward process. Through the years we have developed a series of reagents, tools and protocols to characterize peptide-specific CTL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::25517b208c38cbe40403ecdbac68ea50
http://orbit.dtu.dk/en/publications/tracking-the-elusive-cytotoxic-t-cell-response-in-pigs(a755e4e8-0ed3-4032-9b51-fbc319ac9329).html

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Establishing the pig as a large animal model for vaccine development against human cancer

Autor: Gregers Jungersen, Simon Welner, Thomas Mørch Frøsig, Maria Rathmann Sørensen, Nana Haahr Overgaard, Mette Ilsøe, Søren Buus, Mads Hald Andersen, Michael R. Rasmussen

Publikováno v: Frontiers in Genetics, Vol 6 (2015)
Overgaard, N H, Frøsig, T M, Welner, S, Rasmussen, M, Ilsøe, M, Sørensen, M R, Andersen, M H, Buus, S & Jungersen, G 2015, ' Establishing the pig as a large animal model for vaccine development against human cancer ', Frontiers in Genetics, vol. 6, 286 . https://doi.org/10.3389/fgene.2015.00286
Frontiers in Genetics

Immunotherapy has increased overall survival of metastatic cancer patients, and cancer antigens are promising vaccine targets. To fulfill the promise, appropriate tailoring of the vaccine formulations to mount in vivo cytotoxic T cell (CTL) responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851da4d168887f44aa33caff4079f8d8
https://doi.org/10.3389/fgene.2015.00286

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Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

Autor: Henning Locht, Simon Welner, Nicole Hartwig Trier, Paul R. Hansen, Morten Frisch, Gunnar Houen

Publikováno v: Molecular Cancer

Background Centromere protein-F (CENP-F) is a large nuclear protein of 367 kDa, which is involved in multiple mitosis-related events such as proper assembly of the kinetochores, stabilization of heterochromatin, chromosome alignment and mitotic check

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22def81e42909889823cb4be47bf872
https://doi.org/10.1186/1476-4598-12-95

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Identification and mapping of a linear epitope of centromere protein F using monoclonal antibodies

Autor: Simon, Welner, Nicole H, Trier, Gunnar, Houen, Paul R, Hansen

Publikováno v: Journal of peptide science : an official publication of the European Peptide Society. 19(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5484238c93b9c02b25380fa8ca768e18
https://pubmed.ncbi.nlm.nih.gov/23297090

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The pig as a model for therapeutic human anti-cancer vaccine development, elucidating the T-cell reactivity against IDO and RhoC

Autor: Nana Haahr Overgaard, Thomas Mørch Frøsig, Simon Welner, Michael Rasmussen, Mette Ilsøe, Maria Rathmann Sørensen, Mads Hald Andersen, Søren Buus, Gregers Jungersen

Publikováno v: Technical University of Denmark Orbit
Overgaard, N H, Frøsig, T M, Welner, S, Rasmussen, M, Ilsøe, M, Sørensen, M R, Andersen, M H, Buus, S & Jungersen, G 2015, ' The pig as a model for therapeutic human anti-cancer vaccine development, elucidating the T-cell reactivity against IDO and RhoC ', 5th European Veterinary Immunology Workshop, Vienna, Austria, 02/09/2015-04/09/2015 .

Immunotherapy against cancer has shown increased overall survival of metastatic cancer patients and is a promising new vaccine target. For this to succeed, appropriate tailoring of vaccine formulations to mount in vivo cytotoxic T cell (CTL) response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ce5f9a1472ac9c949cbf9d4b2b168591
https://orbit.dtu.dk/en/publications/ac7d253f-ced9-49a3-8c6f-a1ff7d265e29

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The pig as a large preclinical model for therapeutic human anti-cancer vaccine development

Autor: Nana Haahr Overgaard, Thomas Mørch Frøsig, Simon Welner, Michael Rasmussen, Jeanne Toft Jakobsen, Mette Ilsøe, Maria Rathmann Sørensen, Andersen, Mads H., Søren Buus, Dennis Christensen, Gregers Jungersen

Publikováno v: Technical University of Denmark Orbit
Overgaard, N H, Frøsig, T M, Welner, S, Rasmussen, M, Jakobsen, J T, Ilsøe, M, Sørensen, M R, Andersen, M H, Buus, S, Christensen, D & Jungersen, G 2016, ' The pig as a large preclinical model for therapeutic human anti-cancer vaccine development ' 11th International Veterinary Immunology Symposium, Gold Coast, Australia, 16/08/2016-19/08/2016, .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d0a9b68e10390450f1e53aeab6a28048
https://orbit.dtu.dk/en/publications/46e8aff7-dc5d-408f-8234-1e270dbc5944

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