FIXED-DURATION VENETOCLAX PLUS OBINUTUZUMAB IMPROVES PFS AND MINIMAL RESIDUAL DISEASE NEGATIVITY IN PATIENTS WITH PREVIOUSLY UNTREATED CLL AND COMORBIDITIES

Autor: Mark Dixon, Maneesh Tandon, C. Utoft Niemann, Liliya Sivcheva, Karl-Anton Kreuzer, Kathryn Humphrey, Laura M. Fogliatto, Simon Warburton, Sue Robinson, Anthonie Willem Langerak, C M Wendtner, Eugen Tausch, Barbara Eichhorst, Anna Marina Liberati, Robert Weinkove, Sandra Robrecht, Stephan Stilgenbauer, Kirsten Fischer, Javier Pinilla-Ibarz, Mehrdad Mobasher, M. Porro Lurà, Matthias Ritgen, Valentin Goede, Thomas J. Kipps, William Schary, Sebastian Boettcher, Michael Hallek, K. Le Dû, Stephen Opat, Othman Al-Sawaf, A. M. Fink, Jasmin Bahlo, Olga Samoylova

Publikováno v: Hematological Oncology. 37:82-84

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6058960fee67ca2d46c10b3b69c4a09
https://doi.org/10.1002/hon.52_2629

Venetoclax and obinutuzumab in chronic lymphocytic leukemia

Autor: Simon Warburton, Jasmin Bahlo, Eugen Tausch, Sebastian Böttcher, Kirsten Fischer, Javier López, Thomas J. Kipps, Michael Hallek, Lukas Frenzel, Matthias Ritgen, Valentin Goede, Othman Al-Sawaf, Sue Robinson, Anna-Maria Fink, Jacque J.M. Van Dongen, Anton W. Langerak, Stephen Opat, Kathryn Humphrey, Clemens M. Wendtner, Stephan Stilgenbauer, Barbara Eichhorst, Mark Dixon, Carolyn Owen, Rod A. Humerickhouse, Till Seiler, Robert Weinkove, Mehrdad Mobasher

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Blood, 129(19), 2702-2705. American Society of Hematology

To the editor: In chronic lymphocytic leukemia (CLL), the median age at diagnosis is 72 years, and most patients requiring therapy have coexisting medical conditions. Venetoclax is a potent BH3-mimetic compound that selectively antagonizes BCL-2 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc05c7b1b81cb997630e4809873e0a7
https://saludmadrid.ibai.com/handle/20.500.12530/32342

Cell proliferation in the liver and thyroid of C57Bl/10J mice after dietary administration of chlordane

Autor: David A. Jackson, Mairi G. Stewart, Simon Warburton, Alan M. Marsden, Peter Wadsworth, Jacqui Aitchison, Terry C. Orton, Nigel Barrass

Publikováno v: Environmental Health Perspectives

Chlordane is a polychlorinated hydrocarbon that causes liver enlargement and induces mixed-function oxidases similar to those induced by phenobarbitone in the mouse. We have assessed the hepatocarcinogenicity (after 2 years) and the time course (over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b369343c28f4d7c0798298c74a9a67
https://doi.org/10.1289/ehp.93101s5219

Cell Proliferation in the Liver and Thyroid of C57B1/10J Mice after Dietary Administration of Chlordane

Autor: Nigel Barrass, Mairi Stewart, Simon Warburton, Jacqui Aitchison, David Jackson, Peter Wadsworth, Alan Marsden, Terry Orton

Publikováno v: Environmental Health Perspectives. 101:219

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ec6bb8a976a40a063b4339dca560046
https://doi.org/10.2307/3431871