Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Simon Wabitsch"'
Autor:
Yuta Myojin, Justin D. McCallen, Chi Ma, Kylynda C. Bauer, Benjamin Ruf, Mohamed-Reda Benmebarek, Benjamin L. Green, Simon Wabitsch, John C. McVey, Claude Fu, Changqing Xie, Tim F. Greten
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100959- (2024)
Backgrounds & Aims: The efficacy of immune checkpoint inhibitor (ICI) therapy for liver cancer remains limited. As the hypoxic liver environment regulates adenosine signaling, we tested the efficacy of adenosine A2a receptor (A2aR) inhibition in comb
Externí odkaz:
https://doaj.org/article/8a8b8d9041384815ac5be269a8423a00
Autor:
Chi Ma, Tim F Greten, Firouzeh Korangy, Benjamin L Green, Benjamin Ruf, Mohamed-Reda Benmebarek, Yuta Myojin, Jonathan Qi, Simon Wabitsch, Amran Nur, Kylynda C Bauer, Rajiv Trehan, Danielle Springer, Audrey Noguchi, Morteza Peiravi, Heather Potts
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6d696f0757554567bc25be120834fb8e
Autor:
Simon Wabitsch, Wenzel Schoening, Julia-Sophia Bellingrath, Christian Brenzing, Alexander Arnold, Uli Fehrenbach, Moritz Schmelzle, Johann Pratschke
Publikováno v:
Journal of Minimal Access Surgery, Vol 17, Iss 1, Pp 63-68 (2021)
Background: Liver resection is the treatment of choice for patients with localised Caroli disease. While liver resection was traditionally performed as open procedure, this case series aims to evaluate the safety and efficacy of minimally invasive, l
Externí odkaz:
https://doaj.org/article/a8be4d0957764801bc3bdf4f1f60a6fe
Autor:
Simon Wabitsch, Mayank Tandon, Benjamin Ruf, Qianfei Zhang, Justin D. McCallen, John C. McVey, Chi Ma, Benjamin L. Green, Laurence P. Diggs, Bernd Heinrich, Tim F. Greten
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1166-1178 (2021)
Background & Aims: Intrahepatic cholangiocarcinoma (iCCA) accounts for a fraction of primary liver cancers but has a 5-year survival rate of only 10%. Immune checkpoint inhibitors are effective in treating many solid cancers, but immune checkpoint in
Externí odkaz:
https://doaj.org/article/7653432cbbe048aa9d6e9262cb8dbb33
Autor:
John C. McVey, Benjamin L. Green, Benjamin Ruf, Justin D. McCallen, Simon Wabitsch, Varun Subramanyam, Laurence P. Diggs, Bernd Heinrich, Tim F. Greten, Chi Ma
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103847- (2022)
Summary: Non-alcoholic fatty liver disease (NAFLD) has become an important etiology leading to liver cancer. NAFLD alters adaptive T cell immunity and has a profound influence on liver cancer development. However, it is unclear how NAFLD affects tumo
Externí odkaz:
https://doaj.org/article/a5729820c7ea4f7fa2e4a3f196e9671e
Autor:
Julius Maximilian Plewe, Simon Wabitsch, Felix Krenzien, Philipp Haber, Timm Denecke, Bernhard Gebauer, Robert Öllinger, Johann Pratschke, Moritz Schmelzle
Publikováno v:
Journal of Minimal Access Surgery, Vol 16, Iss 2, Pp 185-189 (2020)
Objective: Portal vein embolisation (PVE) represents the standard procedure for augmentation of the contralateral lobe before extended right hepatectomy. However, possible limitations for the percutaneous transhepatic approach exist, for example, lar
Externí odkaz:
https://doaj.org/article/a3f325e88e964496b5bb2ab9ee806faa
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100517- (2021)
Summary: Immunomodulatory drugs can alter lymphocyte function. Hydroxychloroquine (HCQ) is prescribed for many autoimmune diseases and is under investigation as an anti-tumor autophagy inhibitor. Here, we describe a protocol to evaluate the influence
Externí odkaz:
https://doaj.org/article/54a27c8e94314bb2bdad87710812b00e
Autor:
Simon Wabitsch, John C. McVey, Chi Ma, Benjamin Ruf, Olena Kamenyeva, Justin D. McCallen, Laurence P. Diggs, Bernd Heinrich, Tim F. Greten
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101990- (2021)
Summary: Hydroxychloroquine (HCQ) is a well-known anti-inflammatory drug but is also known as an anti-inflammatory drug. Here, we evaluate the influence of HCQ treatment on the effect of anti-PD1 tumor immunotherapy. Anti-PD1 therapy-sensitive tumor
Externí odkaz:
https://doaj.org/article/d82811e1bbf545b393e42c4d2cd936b5
Autor:
Simon Wabitsch, Justin D. McCallen, Olena Kamenyeva, Benjamin Ruf, John C. McVey, Juraj Kabat, Juliane S. Walz, Yaron Rotman, Kylynda C. Bauer, Amanda J. Craig, Marie Pouzolles, Ira Phadke, Vanessa Catania, Benjamin L. Green, Claude Fu, Laurence P. Diggs, Bernd Heinrich, Xin Wei Wang, Chi Ma, Tim F. Greten
Publikováno v:
Journal of Hepatology. 77:748-760
Autor:
Tim F. Greten, Daniel L. Barber, Clifton E. Barry, Sangmi Oh, Shunsuke Sakai, Raj Chari, Christine N. Evans, Marie Pouzolles, Linda L. Cui, Varun Subramanyam, Bernd Heinrich, Qianfei Zhang, Laurence P. Diggs, Chi Ma, Simon Wabitsch, Vanessa V. Catania, Benjamin Ruf
Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells that recognize non-peptide antigens including riboflavin derivates. Although in vitro–activated MAIT cells show antitumor activity, the in vivo role of MAIT cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45dd66d0500f2ac40de215037fd687c8
https://doi.org/10.1158/2326-6066.c.6550414.v1
https://doi.org/10.1158/2326-6066.c.6550414.v1