Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Simon W. M. Eng"'
Autor:
Cory Stingl, Jeffrey A. Dvergsten, Simon W. M. Eng, Rae S. M. Yeung, Marvin J. Fritzler, Thomas Mason, Cynthia Crowson, Deepak Voora, Ann M. Reed
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 8, Pp 671-681 (2022)
Objective The study objective was to identify differences in gene expression between treatment responders (TRs) and treatment non‐responders (TNRs) diagnosed with juvenile dermatomyositis (JDM). Methods Gene expression analyses were performed using
Externí odkaz:
https://doaj.org/article/2eb17506c6c343138e40c5679d1dae1c
Autor:
Simon W. M. Eng, Jeannette M. Olazagasti, Anna Goldenberg, Cynthia S. Crowson, Chester V. Oddis, Timothy B. Niewold, Rae S. M. Yeung, Ann M. Reed
Publikováno v:
ACR Open Rheumatology, Vol 2, Iss 3, Pp 158-166 (2020)
Objective Published predictive models of disease outcomes in idiopathic inflammatory myopathies (IIMs) are sparse and of limited accuracy due to disease heterogeneity. Computational methods may address this heterogeneity by partitioning patients base
Externí odkaz:
https://doaj.org/article/9d92f243072c471780161d15beb82080
Autor:
Florence A. Aeschlimann, Simon W. M. Eng, Shehla Sheikh, Ronald M. Laxer, Diane Hebert, Damien Noone, Marinka Twilt, Christian Pagnoux, Susanne M. Benseler, Rae S. M. Yeung
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-10 (2017)
Abstract Background Takayasu arteritis (TAK) is a large vessel vasculitis that rarely affects children. Data on childhood TAK are scarce. The aim of this study was to analyze the presenting features, course and outcome of children with TAK, compare e
Externí odkaz:
https://doaj.org/article/1b9e4cf6327049aa95a1f41c1ce06f42
Autor:
Jennifer J Y, Lee, Simon W M, Eng, Jaime, Guzman, Ciáran M, Duffy, Lori B, Tucker, Kiem, Oen, Rae S M, Yeung, Brian M, Feldman
Publikováno v:
Arthritis & Rheumatology. 74:1409-1419
The aim of the Paediatric Rheumatology International Trials Organisation (PRINTO) juvenile idiopathic arthritis (JIA) classification criteria, which is still in development, is to identify homogeneous groups of JIA patients. This study was undertaken
Autor:
Adam M. Huber, Anthony Kusalik, Roman Jurencak, Daniel J. Hogan, Susan Tupper, Shirley M. L. Tse, Lynn Spiegel, Ciarán M. Duffy, Rosie Scuccimarri, Stephen W. Scherer, Kimberly Morishita, Suzanne E. Ramsey, Jaime Guzman, Kristin Houghton, Regina M. Taylor-Gjevre, Elizabeth Stringer, John R. Gordon, Ronald M. Laxer, Bianca Lang, David A. Cabral, Richard F. Wintle, Paul Dancey, Alan M. Rosenberg, Brett Trost, Sarah Campillo, Gilles Boire, Simon W. M. Eng, Kiem Oen, Elham Rezaei, Stuart E. Turvey, Rae S. M. Yeung, Anne-Laure Chetaille, Ross E. Petty, Lori B. Tucker, Karen Watanabe Duffy, Gaëlle Chédeville
Publikováno v:
Rheumatology. 59:1066-1075
Objective To identify discrete clusters comprising clinical features and inflammatory biomarkers in children with JIA and to determine cluster alignment with JIA categories. Methods A Canadian prospective inception cohort comprising 150 children with
Publikováno v:
Expert Rev Clin Immunol
Juvenile idiopathic arthritis (JIA) encompasses a heterogeneous group of inflammatory disorders linked by chronic joint inflammation [1]. Stratifying patients in a logical manner would improve the ...
Autor:
Jeannette M. Olazagasti, Anna Goldenberg, Timothy B. Niewold, Chester V. Oddis, Cynthia S. Crowson, Simon W. M. Eng, Rae S. M. Yeung, Ann M. Reed
Publikováno v:
ACR Open Rheumatology
ACR Open Rheumatology, Vol 2, Iss 3, Pp 158-166 (2020)
ACR Open Rheumatology, Vol 2, Iss 3, Pp 158-166 (2020)
Objective Published predictive models of disease outcomes in idiopathic inflammatory myopathies (IIMs) are sparse and of limited accuracy due to disease heterogeneity. Computational methods may address this heterogeneity by partitioning patients base
Autor:
Florence A. Aeschlimann, Simon W. M. Eng, Rae S. M. Yeung, Mira van Veenendaal, Roberta A. Berard, Quaid Morris, Alan M. Rosenberg
Publikováno v:
PLoS Medicine, Vol 16, Iss 2, p e1002750 (2019)
Paediatrics Publications
PLoS Medicine
Paediatrics Publications
PLoS Medicine
Background Joint inflammation is the common feature underlying juvenile idiopathic arthritis (JIA). Clinicians recognize patterns of joint involvement currently not part of the International League of Associations for Rheumatology (ILAR) classificati
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Objective Childhood arthritis encompasses a heterogeneous family of diseases. Significant variation in clinical presentation remains despite consensus-driven diagnostic classifications. Developments in data analysis provide powerful tools for interro
Autor:
Marc R. Fabian, Simon W. M. Eng, Jean-François Côté, Wade H. Dunham, Halil Bagci, Mikhail Bashkurov, Quaid Morris, Graham MacLeod, Ginny I. Chen, James D.R. Knight, Ji-Young Youn, Bhavisha Rathod, Stephane Angers, Anne-Claude Gingras, Seo Jung Hong
Publikováno v:
Molecular cell. 69(3)
mRNA processing, transport, translation, and ultimately degradation involve a series of dedicated protein complexes that often assemble into large membraneless structures such as stress granules (SGs) and processing bodies (PBs). Here, systematic in