Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Simon W Walker"'
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 57:7-25
Proprotein convertase subtilisin kexin 9 (PCSK9) is a serine protease with a key role in regulating plasma low-density lipoprotein (LDL) concentration. Since its discovery via parallel molecular biology and clinical genetics studies in 2003, work to
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 52:680-684
Familial hypercholesterolaemia, one of the most common inherited diseases in the general population, is associated with mutations in at least three different genes including the low density lipoprotein receptor ( LDLR), apolipoprotein B ( APOB) and p
Publikováno v:
Clinical Neuropharmacology. 35:244-253
Objective: Systematic assessment of the prevalence and pattern of liver function test (LFT) abnormalities associated with regular antipsychotics in adult humans and consideration of management of such abnormalities. Data Sources: Systematic search id
Autor:
Clement K M Ho, Robert Finnie, Sara Jenks, Christine Bell, Peter Bloomfield, Nicola Shand, Simon W Walker
Publikováno v:
The British Journal of Diabetes & Vascular Disease. 12:243-247
As in other areas of Western Europe, familial hypercholesterolaemia (FH) is one of the most frequent genetic disorders in the UK. Genetic testing for this condition is available in Scotland. This observational study describes the genetic variants fou
Concise yet comprehensive, Clinical Biochemistry Lecture Notes contains all the essential information for students and foundation doctors to understand the biochemical basis of disease and principles of biochemical diagnostics. It presents scientific
Autor:
Simon W Walker, Clement K M Ho
Publikováno v:
Therapeutic advances in drug safety. 3(1)
Inhibitors of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, commonly known as statins, are widely used in both primary and secondary prevention of occlusive cardiovascular disease. Statins are effective not only in improving t
Autor:
Simon W. Walker
Publikováno v:
Past & Present. 166:31-65
Autor:
Simon W. Walker
Publikováno v:
Speculum. 74:956-991
Richard Andrew was a prominent member of the small but distinguished group of churchmen, educated at the twin foundations of Winchester and New College, whose collective contribution did much to shape Lancastrian policy toward the government of both
Autor:
Simon W. Walker
Publikováno v:
History. 84:31-51
This article considers the case of Janico Dartasso, a Navarrese esquire who pursued a long and generally successful career in the service of the English crown. Rising from the ranks of the men-at-arms employed as garrison soldiers, Janico established
Publikováno v:
Endocrine Research. 24:769-772
Previous reports have suggested a possible dopaminergic inhibition of the actions of AII on aldosterone secretion via adenylate-cyclase inhibitory 'D2' receptors. Others suggest a possible stimulation of aldosterone secretion via a stimulatory 'D1' r