Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Simon W Walker"'
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 57:7-25
Proprotein convertase subtilisin kexin 9 (PCSK9) is a serine protease with a key role in regulating plasma low-density lipoprotein (LDL) concentration. Since its discovery via parallel molecular biology and clinical genetics studies in 2003, work to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f3edae889a3556bfd3c5382ac42eb6
https://doi.org/10.1177/0004563219864379
https://doi.org/10.1177/0004563219864379
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 52:680-684
Familial hypercholesterolaemia, one of the most common inherited diseases in the general population, is associated with mutations in at least three different genes including the low density lipoprotein receptor ( LDLR), apolipoprotein B ( APOB) and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69811415cb997cf80974ad292facb41
https://doi.org/10.1177/0004563215572702
https://doi.org/10.1177/0004563215572702
Autor:
Clement K M Ho, Robert Finnie, Sara Jenks, Christine Bell, Peter Bloomfield, Nicola Shand, Simon W Walker
Publikováno v:
The British Journal of Diabetes & Vascular Disease. 12:243-247
As in other areas of Western Europe, familial hypercholesterolaemia (FH) is one of the most frequent genetic disorders in the UK. Genetic testing for this condition is available in Scotland. This observational study describes the genetic variants fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed60c0d0b8b28756b1af171416472f19
https://doi.org/10.1177/1474651412466272
https://doi.org/10.1177/1474651412466272
Publikováno v:
Clinical Neuropharmacology. 35:244-253
Objective: Systematic assessment of the prevalence and pattern of liver function test (LFT) abnormalities associated with regular antipsychotics in adult humans and consideration of management of such abnormalities. Data Sources: Systematic search id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172c9c7af786e6705cf132d1d545169a
https://doi.org/10.1097/wnf.0b013e31826818b6
https://doi.org/10.1097/wnf.0b013e31826818b6
Concise yet comprehensive, Clinical Biochemistry Lecture Notes contains all the essential information for students and foundation doctors to understand the biochemical basis of disease and principles of biochemical diagnostics. It presents scientific
Autor:
Simon W Walker, Clement K M Ho
Publikováno v:
Therapeutic advances in drug safety. 3(1)
Inhibitors of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, commonly known as statins, are widely used in both primary and secondary prevention of occlusive cardiovascular disease. Statins are effective not only in improving t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03542bdf267fcbdb2cad062e0fc71c8e
https://pubmed.ncbi.nlm.nih.gov/25083224
https://pubmed.ncbi.nlm.nih.gov/25083224
Autor:
Simon W. Walker
Publikováno v:
Past & Present. 166:31-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7cd7e5797fe6535b9fcf80c1d74577e
https://doi.org/10.1093/past/166.1.31
https://doi.org/10.1093/past/166.1.31
Autor:
Simon W. Walker
Publikováno v:
Speculum. 74:956-991
Richard Andrew was a prominent member of the small but distinguished group of churchmen, educated at the twin foundations of Winchester and New College, whose collective contribution did much to shape Lancastrian policy toward the government of both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b84f10927157a291606ca8325aa604d9
https://doi.org/10.2307/2886970
https://doi.org/10.2307/2886970
Autor:
Simon W. Walker
Publikováno v:
History. 84:31-51
This article considers the case of Janico Dartasso, a Navarrese esquire who pursued a long and generally successful career in the service of the English crown. Rising from the ranks of the men-at-arms employed as garrison soldiers, Janico established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf794262a1aa3cddd6c1f7fee6bf6c2
https://doi.org/10.1111/1468-229x.00098
https://doi.org/10.1111/1468-229x.00098
Publikováno v:
Endocrine Research. 24:769-772
Previous reports have suggested a possible dopaminergic inhibition of the actions of AII on aldosterone secretion via adenylate-cyclase inhibitory 'D2' receptors. Others suggest a possible stimulation of aldosterone secretion via a stimulatory 'D1' r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b0761c20fabbc22980146e33f237d9
https://doi.org/10.3109/07435809809032685
https://doi.org/10.3109/07435809809032685