Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Simon Völkl"'
Autor:
Ariful Haque Abir, Leonie Weckwerth, Artur Wilhelm, Jana Thomas, Clara M. Reichardt, Luis Munoz, Simon Völkl, Uwe Appelt, Markus Mroz, Raluca Niesner, Anja Hauser, Rebecca Sophie Fischer, Katharina Pracht, Hans-Martin Jäck, Georg Schett, Gerhard Krönke, Dirk Mielenz
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101981- (2024)
Objective: The metabolism of different cells within the same microenvironment can differ and dictate physiological or pathological adaptions. Current single-cell analysis methods of metabolism are not label-free. Methods: The study introduces a label
Externí odkaz:
https://doaj.org/article/5b381a534cf04e8f9f71a6a2532ba488
Autor:
Alexander Biedermann, Maria Patra-Kneuer, Dimitrios Mougiakakos, Maike Büttner-Herold, Doris Mangelberger-Eberl, Johannes Berges, Christian Kellner, Sarah Altmeyer, Jörg Thomas Bittenbring, Christian Augsberger, Kristina Ilieva-Babinsky, Stefan Haskamp, Fabian Beier, Christopher Lischer, Julio Vera, Anja Lührmann, Simone Bertz, Simon Völkl, Benedikt Jacobs, Stefan Steidl, Andreas Mackensen, Heiko Bruns
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Macrophages are one of the key mediators of the therapeutic effects exerted by monoclonal antibodies, such as the anti-CD19 antibody tafasitamab, approved in combination with lenalidomide for the treatment of relapsed or refractory (r/r) diffuse larg
Externí odkaz:
https://doaj.org/article/83e0d53a47ba41ce83058f40a666be1f
Autor:
Elisabeth Naschberger, Maximilian Fuchs, Nicholas Dickel, Meik Kunz, Bernt Popp, Charles Gwellem Anchang, Richard Demmler, Yanmin Lyu, Steffen Uebe, Arif Bülent Ekici, Carol Immanuel Geppert, Arndt Hartmann, Christian Flierl, Katja Petter, Tobias Gass, Simon Völkl, Michael Scharl, Andreas Ramming, Claudia Günther, Susanne Merkel, Vera Simone Schellerer, Michael Stürzl
Publikováno v:
Cancer Communications, Vol 43, Iss 11, Pp 1280-1285 (2023)
Externí odkaz:
https://doaj.org/article/b5897fea14a54e958b01f425353926f6
Autor:
Daniel Nunez, Darshil Patel, Jenell Volkov, Steven Wong, Zachary Vorndran, Fabian Müller, Michael Aigner, Simon Völkl, Andreas Mackensen, Georg Schett, Samik Basu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101104- (2023)
Chimeric antigen receptor (CAR) T cells targeting CD19+ B cells have demonstrated efficacy in refractory systemic lupus erythematosus (SLE). Although initial clinical data suggest that anti-CD19 CAR T cell therapy is well tolerated and highly effecti
Externí odkaz:
https://doaj.org/article/0226c9915d6d459eb5c58c1b5608d0c9
Autor:
Silja Richter, Martin Böttcher, Simon Völkl, Andreas Mackensen, Evelyn Ullrich, Benedikt Jacobs, Dimitrios Mougiakakos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Previous studies indicated a role of the reconstituting immune system for disease outcome upon high-dose chemotherapy (HDCT) and autologous stem cell transplantation (auto-SCT) in multiple myeloma (MM) and lymphoma patients. Since immune cel
Externí odkaz:
https://doaj.org/article/3aaf292587c54a5393bcac24c5236c94
Autor:
Sebastian Zundler, Francesco Vitali, Soraya Kharboutli, Simon Völkl, Iris Polifka, Andreas Mackensen, Raja Atreya, Markus F. Neurath, Dimitrios Mougiakakos
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Chimeric antigen receptor (CAR) T cell therapy has become a new mainstay in the treatment of several hematologic malignancies, but the spectrum of associated complications is still incompletely defined. Here, we report the case of a 70-year-old femal
Externí odkaz:
https://doaj.org/article/42dee58b8474466b9ab7b7acac47b13e
Autor:
Regina Jitschin, Simon Völkl, Andreas Mackensen, Dimitrios Mougiakakos, Andreas Gießl, Heiko Bruns, Martin Böttcher, Rebecca Baur, Andrej Stoll, Thomas Fischer, Franziska Karl, Romy Böttcher-Loschinski, Cindy Flamann, Ursula Schlötzer-Schrehardt, Denis M Schewe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents the only curative treatment option for a number of hemato-oncological disorders. In fact, allo-HSCT is considered as one of the most successful immunotherapies as its clinical
Externí odkaz:
https://doaj.org/article/03f44df1f3a242ae85281eb8bc2b8891
Autor:
María Fernanda Lammoglia Cobo, Julia Ritter, Regina Gary, Volkhard Seitz, Josef Mautner, Michael Aigner, Simon Völkl, Stefanie Schaffer, Stephanie Moi, Anke Seegebarth, Heiko Bruns, Wolf Rösler, Kerstin Amann, Maike Büttner-Herold, Steffen Hennig, Andreas Mackensen, Michael Hummel, Andreas Moosmann, Armin Gerbitz
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010206 (2022)
Reconstitution of the T cell repertoire after allogeneic stem cell transplantation is a long and often incomplete process. As a result, reactivation of Epstein-Barr virus (EBV) is a frequent complication that may be treated by adoptive transfer of do
Externí odkaz:
https://doaj.org/article/55ec7bb4d6a64ff5b734714b6b22f290
Autor:
Regina Jitschin, Simon Völkl, Andreas Mackensen, Dimitrios Mougiakakos, Daniela Schmidt, Maike Büttner-Herold, Rebecca Baur, Soraya Kharboutli, Andrej Stoll, Wolf Rösler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Chimeric antigen receptor (CAR)-modified T-cells targeting CD19 represent a promising therapy for relapsed or refractory (r/r) lymphoma and leukemia. The most common adverse events are immune related and include cytokine release syndrome and neurotox
Externí odkaz:
https://doaj.org/article/3a73d5b864f04cb082724c98e4cd6d5d
Autor:
Tanja M. Müller, Emily Becker, Maximilian Wiendl, Lisa Lou Schulze, Caroline Voskens, Simon Völkl, Andreas E. Kremer, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundInfection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a wide range of symptoms including gastrointestinal manifestations, and intestinal epithelial cells are a target of the virus. However, it is unkno
Externí odkaz:
https://doaj.org/article/aa7dc904cbf64fedb1240afb7bb42d87