Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: the trigeminal neuralgia experience

Autor: Joanna M. Zakrzewska, Joanne Palmer, Lars Bendtsen, Giulia Di Stefano, Dominik A. Ettlin, Stine Maarbjerg, Mark Obermann, Valerie Morisset, Deb Steiner, Simon Tate, Giorgio Cruccu

Publikováno v: Trials, Vol 19, Iss 1, Pp 1-10 (2018)

Abstract Background This study aimed to describe recruitment challenges encountered during a phase IIa study of vixotrigine, a state and use-dependent Nav1.7 channel blocker, in individuals with trigeminal neuralgia. Methods This was an international

Externí odkaz: https://doaj.org/article/b1e70077314547bc85cf2a9056d7a403

Anthropogenic emissions or just a lot of hot air? Using air pollution to teach quantitative methods to 'mathophobic' first-year geography students

Autor: Alison Copeland, Simon Tate

Publikováno v: Journal of Geography in Higher Education. :1-12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4b0b52e88f0e93413f2b6dfa70711db
https://doi.org/10.1080/03098265.2022.2045576

Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations

Autor: Robert R. Edwards, Kristin L. Schreiber, Robert H. Dworkin, Dennis C. Turk, Ralf Baron, Roy Freeman, Troels S. Jensen, Alban Latremoliere, John D. Markman, Andrew S.C. Rice, Michael Rowbotham, Roland Staud, Simon Tate, Clifford J. Woolf, Nick A. Andrews, Daniel B. Carr, Luana Colloca, Doina Cosma-Roman, Penney Cowan, Luda Diatchenko, John Farrar, Jennifer S. Gewandter, Ian Gilron, Robert D. Kerns, Serge Marchand, Gwendolyn Niebler, Kushang V. Patel, Lee S. Simon, Tina Tockarshewsky, Geertrui F. Vanhove, Daniel Vardeh, Gary A. Walco, Ajay D. Wasan, Ursula Wesselmann

Publikováno v: Edwards, R R, Schreiber, K L, Dworkin, R H, Turk, D C, Baron, R, Freeman, R, Jensen, T S, Latremoliere, A, Markman, J D, Rice, A S C, Rowbotham, M, Staud, R, Tate, S, Woolf, C J, Andrews, N A, Carr, D B, Colloca, L, Cosma-Roman, D, Cowan, P, Diatchenko, L, Farrar, J, Gewandter, J S, Gilron, I, Kerns, R D, Marchand, S, Niebler, G, Patel, K V, Simon, L S, Tockarshewsky, T, Vanhove, G F, Vardeh, D, Walco, G A, Wasan, A D & Wesselmann, U 2023, ' Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain : IMMPACT Review and Recommendations ', Journal of Pain, vol. 24, no. 2, pp. 204-225 . https://doi.org/10.1016/j.jpain.2022.08.010

Large variability in the individual response to even the most-efficacious pain treatments is observed clinically, which has led to calls for a more personalized, tailored approach to treating patients with pain (i.e., "precision pain medicine"). Prec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910e379b8ad13287fcec79441a856441
https://pubmed.ncbi.nlm.nih.gov/36198371

New to teaching geography

Autor: Lynda Yorke, Simon Tate, Martin Davis

Geography plays a crucial role in understanding our world. It makes a vital contribution to our knowledge of the rapidly changing environmental and social challenges facing us and how we should tackle them. Supporting them effectively can present mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96e492d10a54a476aaf4f810fbd09bfc
https://doi.org/10.55203/gvkz5128

A Special Relationship? : British Foreign Policy in the Era of American Hegemony

Autor: Simon Tate

This book addresses the special relationship from the perspective of post-Second World War British governments. It asks how they have perceived the special relationship and performed a foreign policy role within it? This enables the book to argue tha