Aptamer proteomics of serum exosomes from patients with Primary Raynaud's and patients with Raynaud's at risk of evolving into Systemic Sclerosis.

Autor: Sonsoles Piera-Velazquez, Simon T Dillon, Xuesong Gu, Towia A Libermann, Sergio A Jimenez

Publikováno v: PLoS ONE, Vol 17, Iss 12, p e0279461 (2022)

BackgroundA major unmet need for Systemic Sclerosis (SSc) clinical management is the lack of biomarkers for the early diagnosis of patients with Raynaud's Phenomenon at high risk of evolving into SSc.ObjectiveTo identify proteins contained within ser

Externí odkaz: https://doaj.org/article/c56ec960cdd242d3820496881cdee3a7

Aptamer-Based Proteomics Measuring Preoperative Cerebrospinal Fluid Protein Alterations Associated with Postoperative Delirium

Autor: Simon T. Dillon, Sarinnapha M. Vasunilashorn, Hasan H. Otu, Long Ngo, Tamara Fong, Xuesong Gu, Michele Cavallari, Alexandra Touroutoglou, Mouhsin Shafi, Sharon K. Inouye, Zhongcong Xie, Edward R. Marcantonio, Towia A. Libermann

Publikováno v: Biomolecules, Vol 13, Iss 9, p 1395 (2023)

Delirium is a common postoperative complication among older patients with many adverse outcomes. Due to a lack of validated biomarkers, prediction and monitoring of delirium by biological testing is not currently feasible. Circulating proteins in cer

Externí odkaz: https://doaj.org/article/bb2419d550e8401db3bd11a1ec37db0e

The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile

Autor: Tammy T. Hshieh, Sarinnapha M. Vasunilashorn, Madeline L. D'Aquila, Steven E. Arnold, Bradford C. Dickerson, Tamara G. Fong, Richard N. Jones, Edward R. Marcantonio, Eva M. Schmitt, Guoquan Xu, Yun Gou, Fan Chen, Lisa J. Kunze, Kamen V. Vlassakov, Ayesha R. Abdeen, Jeffrey K. Lange, Brandon E. Earp, Alexandra Touroutoglou, Becky C. Carlyle, Pia Kivisakk‐Webb, Thomas G. Travison, Simon T. Dillon, Towia A. Libermann, Sharon K. Inouye, RISE Study Group, Steven Arnold, Bradford Dickerson, Tamara Fong, Richard Jones, Thomas Travison, Michele Cavallari, Jacob Hooker, Tammy Hshieh, Savannah Kandigian, Long Ngo, Hasan Otu, Bianca Trombetta, Sarinnapha Vasunilashorn, Ayesha Abdeen, Douglas Ayres, Brandon Earp, Jeffrey Lange, Gregory Brick, Antonia Chen, Robert Davis, Jacob Drew, Richard Iorio, Fulton Kornack, Michael Weaver, Anthony Webber, Richard Wilk, Lisa Kunze, David Shaff, Kamen Vlassakov, Brett Armstrong, Angelee Banda, Sylvie Bertrand, Madeline D'Aquila, Jacqueline Gallagher, Baileigh Hightower, Shannon Malloy, Jacqueline Nee, Chloe Nobuhara, Abigail Overstreet, Annie Racine, David Urick, Grae Arabasz, Michael Brickhouse, Regan Butterfield, Shirley Hsu, Sara Makaretz, Judit Sore, Douglas Tommet, Sabrina Carretie, Ted Gruen, Katherine Tasker

Publikováno v: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 752-762 (2019)

Abstract Introduction The Role of Inflammation after Surgery for Elders study correlates novel inflammatory markers measured in blood, cerebrospinal fluid (CSF) assays, and [11C]‐PBR28 positron‐emission tomography imaging. Methods This study invo

Externí odkaz: https://doaj.org/article/b778d4458ac14bf5af9509298ab701af

Patterns and Persistence of Perioperative Plasma and Cerebrospinal Fluid Neuroinflammatory Protein Biomarkers After Elective Orthopedic Surgery Using SOMAscan

Autor: Simon T, Dillon, Hasan H, Otu, Long H, Ngo, Tamara G, Fong, Sarinnapha M, Vasunilashorn, Zhongcong, Xie, Lisa J, Kunze, Kamen V, Vlassakov, Ayesha, Abdeen, Jeffrey K, Lange, Brandon E, Earp, Zara R, Cooper, Eva M, Schmitt, Steven E, Arnold, Tammy T, Hshieh, Richard N, Jones, Sharon K, Inouye, Edward R, Marcantonio, Towia A, Libermann, Katherine, Tasker

Publikováno v: Anesthesia and analgesia.

The neuroinflammatory response to surgery can be characterized by peripheral acute plasma protein changes in blood, but corresponding, persisting alterations in cerebrospinal fluid (CSF) proteins remain mostly unknown. Using the SOMAscan assay, we de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7f699a6f9fad158fd4c902daf27d1b
https://pubmed.ncbi.nlm.nih.gov/35389379

Circulating proteomic profiles associated with endometriosis in adolescents and young adults

Autor: Naoko Sasamoto, Long Ngo, Allison F Vitonis, Simon T Dillon, Stacey A Missmer, Towia A Libermann, Kathryn L Terry

Publikováno v: Hum Reprod

STUDY QUESTION What are the systemic molecular profiles of endometriosis diagnosed in adolescents and young adults? SUMMARY ANSWER Significant enrichment and increased activation of proteins related to angiogenesis and cell migration pathways were ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422ddbfe8d02a2b41763bab7c59f4b0c
https://doi.org/10.1093/humrep/deac146