Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Simon T Barry"'
Autor:
Matthew King, Melissa Chapman, Vasu Sah, Paul Lyne, Alexey Revenko, Charles Sinclair, Ben Johnson, Maneesh Singh, Andrew Watt, Maelle Mairesse, Larissa S Carnevalli, Alison Peter, Molly Taylor, Lisa Hettrick, Stephanie Klein, Anisha Solanki, Danielle Gattis, Adina M Hughes, Lukasz Magiera, Gozde Kar, Lucy Ireland, Deanna A Mele, Josephine Walton, Mark Edbrooke, Simon T Barry, Stephen Fawell, Frederick W Goldberg, A Robert MacLeod
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/f65818566663472ca06c1db1ef39c009
Autor:
Nikita Sushentsev, Gregory Hamm, Lucy Flint, Daniel Birtles, Aleksandr Zakirov, Jack Richings, Stephanie Ling, Jennifer Y. Tan, Mary A. McLean, Vinay Ayyappan, Ines Horvat Menih, Cara Brodie, Jodi L. Miller, Ian G. Mills, Vincent J. Gnanapragasam, Anne Y. Warren, Simon T. Barry, Richard J. A. Goodwin, Tristan Barrett, Ferdia A. Gallagher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Hyperpolarised magnetic resonance imaging (HP-13C-MRI) has shown promise as a clinical tool for detecting and characterising prostate cancer. Here we use a range of spatially resolved histological techniques to identify the biological mechan
Externí odkaz:
https://doaj.org/article/5d269719830146bfb19310f180c8fbe9
Autor:
Elizabeth L. Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa Carnevalli, Fernando J. Calero-Nieto, Gemma N. Jones, Andrew J. Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P. Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J. Carl Barrett, Arsene-Bienvenu Loembé, Serge Y. Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A. Nance, Carlos Alberto Gomez Roca, Elaine Cadogan, Susan E. Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I. Gabrilovich, Simon T. Barry
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The Ataxia telangiectasia and Rad3-related (ATR) inhibitor ceralasertib in combination with the PD-L1 antibody durvalumab demonstrated encouraging clinical benefit in melanoma and lung cancer patients who progressed on immunotherapy. Here we
Externí odkaz:
https://doaj.org/article/189773f2417346dcbdf8b6281d57effa
Autor:
James R Bradford, Matthew Farren, Steve J Powell, Sarah Runswick, Susie L Weston, Helen Brown, Oona Delpuech, Mark Wappett, Neil R Smith, T Hedley Carr, Jonathan R Dry, Neil J Gibson, Simon T Barry
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66003 (2013)
Pre-clinical models of tumour biology often rely on propagating human tumour cells in a mouse. In order to gain insight into the alignment of these models to human disease segments or investigate the effects of different therapeutics, approaches such
Externí odkaz:
https://doaj.org/article/7dfb779fa8d5446c94fc9f95ab1932d3
Autor:
Lorna Hopcroft, Eleanor M. Wigmore, Stuart C. Williamson, Susana Ros, Cath Eberlein, Jennifer I. Moss, Jelena Urosevic, Larissa S. Carnevalli, Sara Talbot, Lauren Bradshaw, Catherine Blaker, Sreeharsha Gunda, Venetia Owenson, Scott Hoffmann, Daniel Sutton, Stewart Jones, Richard J. A. Goodwin, Brandon S. Willis, Claire Rooney, Elza C. de Bruin, Simon T. Barry
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Combining the selective AKT inhibitor, capivasertib, and SERD, fulvestrant improved PFS in a Phase III clinical trial (CAPItello-291), treating HR+ breast cancer patients following aromatase inhibitors, with or without CDK4/6 inhibitors. How
Externí odkaz:
https://doaj.org/article/216706db2e6b4b6eae15d98244910c27
Autor:
Dustin J. Flanagan, Raheleh Amirkhah, David F. Vincent, Nuray Gundaz, Pauline Gentaz, Patrizia Cammareri, Aoife J. McCooey, Amy M. B. McCorry, Natalie C. Fisher, Hayley L. Davis, Rachel A. Ridgway, Jeroen Lohuis, Joshua D. G. Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K. Markert, Douglas Strathdee, Laurent Bartholin, Keara L. Redmond, Emma M. Kerr, Daniel B. Longley, Fiona Ginty, Sanghee Cho, Helen G. Coleman, Maurice B. Loughrey, Alberto Bardelli, Timothy S. Maughan, Andrew D. Campbell, Mark Lawler, Simon J. Leedham, Simon T. Barry, Gareth J. Inman, Jacco van Rheenen, Philip D. Dunne, Owen J. Sansom
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
It remains critical to identify colorectal cancers (CRC) that will disseminate as early as possible. Here, the authors identify CRC tumours that are aggressive and prone to early dissemination, characterised by epithelial TGFβ and growth-factor sign
Externí odkaz:
https://doaj.org/article/685f337608c24440b7e084866104173a
Autor:
Lorna Hopcroft, Eleanor M. Wigmore, Stuart C. Williamson, Susana Ros, Cath Eberlein, Jennifer I. Moss, Jelena Urosevic, Larissa S. Carnevalli, Sara Talbot, Lauren Bradshaw, Catherine Blaker, Sreeharsha Gunda, Venetia Owenson, Scott Hoffmann, Daniel Sutton, Stewart Jones, Richard J. A. Goodwin, Brandon S. Willis, Claire Rooney, Elza C. de Bruin, Simon T. Barry
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/597341a4bba64230b85546c506522cc0
Autor:
Meng Dong, Kathrin Böpple, Julia Thiel, Bernd Winkler, Chunguang Liang, Julia Schueler, Emma J. Davies, Simon T. Barry, Tauno Metsalu, Thomas E. Mürdter, Georg Sauer, German Ott, Matthias Schwab, Walter E. Aulitzky
Publikováno v:
Cells, Vol 12, Iss 5, p 807 (2023)
Precision-cut tumor slices (PCTS) maintain tissue heterogeneity concerning different cell types and preserve the tumor microenvironment (TME). Typically, PCTS are cultured statically on a filter support at an air–liquid interface, which gives rise
Externí odkaz:
https://doaj.org/article/d128b48ef47d4ee0b93d9507b59dc750
Autor:
Dustin J. Flanagan, Raheleh Amirkhah, David F. Vincent, Nuray Gunduz, Pauline Gentaz, Patrizia Cammareri, Aoife J. McCooey, Amy M. B. McCorry, Natalie C. Fisher, Hayley L. Davis, Rachel A. Ridgway, Jeroen Lohuis, Joshua D. G. Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K. Markert, Douglas Strathdee, Laurent Bartholin, Keara L. Redmond, Emma M. Kerr, Daniel B. Longley, Fiona Ginty, Sanghee Cho, Helen G. Coleman, Maurice B. Loughrey, Alberto Bardelli, Timothy S. Maughan, Andrew D. Campbell, Mark Lawler, Simon J. Leedham, Simon T. Barry, Gareth J. Inman, Jacco van Rheenen, Philip D. Dunne, Owen J. Sansom
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d890b609d092453794d4b110a230e27b
Autor:
Simon T. Barry, Dmitry I. Gabrilovich, Owen J. Sansom, Andrew D. Campbell, Jennifer P. Morton
Publikováno v:
Nature Reviews Cancer. 23:216-237