Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Simon Surprenant"'
Autor:
Rina Aharoni, Zulfiqar Ahmad, Suhail Akhtar, N. D. Prasad Atmuri, Carmen Avendaño, Ivneet Banga, Shai Bel, Łukasz Berlicki, Yair Blumberg, Carine Bourguet, Marlon Henrique Cardoso, Samraggi Choudhury, Sitan Diarra, Marvin N. Driessen, Michael K. Dunn, Vandon T. Duong, Offir Ertracht, Emer S. Ferro, Octavio Luiz Franco, Tatiana Galochkina, Sonu Gandhi, Shikun Ge, Jean-Christophe Gelly, Mayara C.F. Gewehr, Rujuta Ghorpade, Eric R. Gross, Wessal Hanout, Tamia A. Harris, Adrienne Joseph, Srinivasaraghavan Kannan, Abidemi Paul Kappo, Krishna Kumar, Maushmi S. Kumar, Dilraj Lama, Jolene L. Lau, Jianguo Li, Adi Litmanovich, Jamie Liu, William D. Lubell, Lloyd Mabonga, Subhasis Mahari, Priscilla Masamba, J. Carlos Menéndez, Gassan Moady, Satheesh Kumar Nanjappan, Ami Navon, Ines Neundorf, Meital Nuriel-Ohayon, Dmitriy Orlov, David Paul, Ron Piran, William Farias Porto, Nir Qvit, Samuel J.S. Rubin, Mussa Saad, Deepshikha Shahdeo, Olga Shamova, Kathleen M. Sicinski, Abhishek Singh, Worood Sirhan, Shruti Surendran, Simon Surprenant, Yaw Sing Tan, Mukesh Thakur, Ekaterina Umnyakova, Özge Ünsal, Chandra S Verma, Nana-Maria Wagner, Zhipeng A. Wang, Bryan J. Xie, Long Xu, Vanessa O. Zambelli, Xiaoying Zhang, Ji-Shen Zheng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd1766f7274d84b4d2ea94b9168ec00
https://doi.org/10.1016/b978-0-12-820141-1.00034-0
https://doi.org/10.1016/b978-0-12-820141-1.00034-0
Autor:
Steven R. LaPlante, René Coulombe, Thao Trinh, Dominik Wernic, Rebekah J. Carson, Nathalie Rioux, Bruno Simoneau, Catherine Chabot, Youla S. Tsantrizos, Jianmin Duan, Simon Surprenant, Pierre R. Bonneau, Carl Thibeault, Stephen W. Mason, Serge Landry, Craig Fenwick, François Bilodeau, Araz Jakalian, Murray D. Bailey, Stephen H. Kawai, Clint James, Yves Bousquet, Bounkham Thavonekham, Michel Garneau, Eric Beaulieu, Sébastien Morin, Christiane Yoakim, Ted Halmos, Lee Fader, Jennifer Tsoung
Publikováno v:
ACS Medicinal Chemistry Letters. 7:797-801
Optimization of pyridine-based noncatalytic site integrase inhibitors (NCINIs) based on compound 2 has led to the discovery of molecules capable of inhibiting virus harboring N124 variants of HIV integrase (IN) while maintaining minimal contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88190548f46d19bc513630aa18caccd
https://doi.org/10.1021/acsmedchemlett.6b00194
https://doi.org/10.1021/acsmedchemlett.6b00194
Autor:
Bruno Simoneau, Oliver Hucke, Ingrid Guse, Martin Duplessis, Alexandre Gagnon, Yves Bousquet, Patrick Deroy, Jianmin Duan, Martin Tremblay, Christopher T. Lemke, Pierre R. Bonneau, Stephen W. Mason, Steve Titolo, Nathalie Goudreau, Stephen H. Kawai, Simon Surprenant, Michel Garneau, Christiane Yoakim
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:7512-7517
A uHTS campaign led to the discovery of a 5-(5-furan-2-ylpyrazol-1-yl)-1H-benzimidazole series that inhibits assembly of HIV-1 capsid. Synthetic manipulations at N1, C2 and C16 positions improved the antiviral potency by a . The X-ray structure of 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4edddc4e78686af2be77d664ae3966
https://doi.org/10.1016/j.bmcl.2012.10.034
https://doi.org/10.1016/j.bmcl.2012.10.034
Publikováno v:
ChemInform. 38
The nucleophilic aromatic substitution reaction between electron-deficient aryl fluorides and terminal alkynes is shown to be efficiently promoted by sodium bis(trimethylsilyl)amide as a base. Moderate to excellent yields of 2-ethynylnitrobenzene pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e86e126c1aaa7ef44d9e062f0f009d
https://doi.org/10.1002/chin.200744059
https://doi.org/10.1002/chin.200744059
Autor:
Simon Surprenant, William D. Lubell
Publikováno v:
Organic letters. 8(13)
[reaction: see text] Macrocyclic and fused bicyclic dipeptides are complementary motifs for mimicry of different types of beta-turn geometry. Macrocyclic dipeptide mimics have served as precursors for the synthesis of their bicyclic counterparts usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746473674b70de656534d54064d5f58a
https://pubmed.ncbi.nlm.nih.gov/16774273
https://pubmed.ncbi.nlm.nih.gov/16774273
Autor:
William D. Lubell, Simon Surprenant
Publikováno v:
The Journal of organic chemistry. 71(2)
[reaction: see text] The 9-(4-bromophenyl)-9-fluorenyl (BrPhF) group has been developed as a novel safety-catch amine protection. This relatively acid-stable protecting group can be successfully activated by palladium-catalyzed cross-coupling reactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0af2424c2b572c037b1ab68af39356
https://pubmed.ncbi.nlm.nih.gov/16409010
https://pubmed.ncbi.nlm.nih.gov/16409010
Publikováno v:
Organic letters. 5(25)
Julia olefination between alpha-alkoxy sulfones 2a-c and a wide variety of ketones or aldehydes afforded substituted vinyl ethers in 46-90% yields. Sulfones 2a-c were readily prepared in two steps from commercially available reagents in 68-80% yields
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70626155c33ad027f85cdb1a82803758
https://pubmed.ncbi.nlm.nih.gov/14653690
https://pubmed.ncbi.nlm.nih.gov/14653690
Publikováno v:
The Journal of Organic Chemistry. 70:4901-4902
[structures: see text] A systematic study was performed to establish general synthesis protocols for forming enantiomerically pure macrocyclic dipeptide lactams. Focusing on macrocycles of 8-, 9-, and 10-membered rings, effective syntheses were achie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c87ed41f8ba3bb0cef19fa30df74743
https://doi.org/10.1021/jo056027o
https://doi.org/10.1021/jo056027o
Publikováno v:
Organic Letters; Jul2007, Vol. 9 Issue 14, p2741-2743, 3p