Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Simon Stücheli"'
Autor:
Michael Weingartner, Simon Stücheli, Fadi Jebbawi, Bruno Gottstein, Guido Beldi, Britta Lundström-Stadelmann, Junhua Wang, Alex Odermatt
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 1, p e0009192 (2022)
BackgroundEchinococcus multilocularis causes alveolar echinococcosis (AE), a rising zoonotic disease in the northern hemisphere. Treatment of this fatal disease is limited to chemotherapy using benzimidazoles and surgical intervention, with frequent
Externí odkaz:
https://doaj.org/article/d23899232fcb418d84717e95bd178581
Impact on Bile Acid Concentrations by Alveolar Echinococcosis and Treatment with Albendazole in Mice
Autor:
Cristina Gómez, Fadi Jebbawi, Michael Weingartner, Junhua Wang, Simon Stücheli, Bruno Stieger, Bruno Gottstein, Guido Beldi, Britta Lundström-Stadelmann, Alex Odermatt
Publikováno v:
Metabolites, Vol 11, Iss 7, p 442 (2021)
Alveolar echinococcosis (AE) caused by Echinococcus multilocularis is a chronic, progressive liver disease widely distributed in the Northern Hemisphere. The main treatment options include surgical interventions and chemotherapy with benzimidazole al
Externí odkaz:
https://doaj.org/article/f081f0502e73402a819f33393e3072d7
Publikováno v:
Metabolites, Vol 10, Iss 7, p 282 (2020)
Bile acids control lipid homeostasis by regulating uptake from food and excretion. Additionally, bile acids are bioactive molecules acting through receptors and modulating various physiological processes. Impaired bile acid homeostasis is associated
Externí odkaz:
https://doaj.org/article/746a74b3ce954ef398b21588cec442b4
Autor:
Odermatt, Simon Stücheli, Selene Araya, Caner Ercan, Seraina O. Moser, John Gallon, Paul Jenö, Salvatore Piscuoglio, Luigi Terracciano, Alex
Publikováno v:
Cancers; Volume 14; Issue 13; Pages: 3074
Prostate cancer (PCa), one of the most common malignancies in men, typically responds to initial treatment, but resistance to therapy often leads to metastases and death. The dehydrogenase/reductase 7 (DHRS7, SDR34C1) is an “orphan” enzyme withou
Autor:
Simon, Stücheli, Selene, Araya, Caner, Ercan, Seraina O, Moser, John, Gallon, Paul, Jenö, Salvatore, Piscuoglio, Luigi, Terracciano, Alex, Odermatt
Publikováno v:
Cancers. 14(13)
Prostate cancer (PCa), one of the most common malignancies in men, typically responds to initial treatment, but resistance to therapy often leads to metastases and death. The dehydrogenase/reductase 7 (DHRS7, SDR34C1) is an "orphan" enzyme without kn
Autor:
Karen E. Chapman, Michael Weingartner, Petra Klusonova, Denise V. Kratschmar, Gareth G. Lavery, Julia Birk, Alex Odermatt, Simon Stücheli
Publikováno v:
British Journal of Pharmacology
BACKGROUND AND PURPOSE 11β-Hydroxysteroid dehydrogenase 1 (11β-HSD1) regulates tissue-specific glucocorticoid metabolism and its impaired expression and activity are associated with major diseases. Pharmacological inhibition of 11β-HSD1 is conside
Autor:
Fadi Jebbawi, Guido Beldi, Alex Odermatt, Michael Weingartner, Simon Stücheli, Bruno Gottstein, Junhua Wang, Britta Lundström-Stadelmann
BackgroundEchinococcus multilocularis causes alveolar echinococcosis (AE), a rising zoonotic disease in the northern hemisphere. Treatment of this fatal disease is limited to chemotherapy using benzimidazoles and surgical intervention, with relativel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc8185582aa8bdd6afef03681af9ef2
https://doi.org/10.1101/2021.02.03.429530
https://doi.org/10.1101/2021.02.03.429530
Publikováno v:
Metabolites
Volume 10
Issue 7
Metabolites, Vol 10, Iss 282, p 282 (2020)
Volume 10
Issue 7
Metabolites, Vol 10, Iss 282, p 282 (2020)
Bile acids control lipid homeostasis by regulating uptake from food and excretion. Additionally, bile acids are bioactive molecules acting through receptors and modulating various physiological processes. Impaired bile acid homeostasis is associated
Autor:
Denise V. Kratschmar, Alex Odermatt, Simon Stücheli, Maria Tsachaki, Selene Araya, Katharina Beck
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 171
DHRS7 (SDR34C1) has been associated with potential tumor suppressor effects in prostate cancer; however, its function remains largely unknown. Recent experiments using purified recombinant human DHRS7 suggested several potential substrates, including