Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Simon Schwingenschuh"'
Autor:
Thomas Birngruber, Kip Vought, Simon Schwingenschuh, Peter Reisenegger, Howard Maibach, Dmitri Lissin
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2563 (2023)
Topical delivery systems (TDSs) enable the direct transport of analgesics into areas of localized pain and thus minimize the side effects of administration routes that rely on systemic drug distribution. For musculoskeletal pain, clinicians frequentl
Externí odkaz:
https://doaj.org/article/779a794117e64313aff5b38654f57c2b
Autor:
Elisabeth Hofmann, Julia Fink, Anita Eberl, Eva-Maria Prugger, Dagmar Kolb, Hanna Luze, Simon Schwingenschuh, Thomas Birngruber, Christoph Magnes, Selma I. Mautner, Lars-Peter Kamolz, Petra Kotzbeck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Burn injuries initiate numerous processes such as heat shock response, inflammation and tissue regeneration. Reliable burn models are needed to elucidate the exact sequence of local events to be able to better predict when local inflammation
Externí odkaz:
https://doaj.org/article/aa79ae995bc14dc48e7d3647aad13c78
Autor:
Judith C. J. Holzer-Geissler, Simon Schwingenschuh, Martin Zacharias, Johanna Einsiedler, Sonja Kainz, Peter Reisenegger, Christian Holecek, Elisabeth Hofmann, Barbara Wolff-Winiski, Hermann Fahrngruber, Thomas Birngruber, Lars-Peter Kamolz, Petra Kotzbeck
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 856 (2022)
The treatment of chronic wounds still challenges modern medicine because of these wounds’ heterogenic pathophysiology. Processes such as inflammation, ischemia and bacterial infection play major roles in the progression of a chronic wound. In recen
Externí odkaz:
https://doaj.org/article/0adb736ea2344004badd2ae3ce9c9c28
Autor:
Pernelle K. Schøndorff, Frank Sinner, Matthias Heschel, Thomas Birngruber, Thomas Altendorfer-Kroath, Simon Schwingenschuh
Publikováno v:
Diabetes Technology & Therapeutics. 21:740-744
Continuous subcutaneous insulin infusion (CSII) is a widely used treatment for diabetes patients. Insulin infusion sets (CSII-catheters) are continuously optimized regarding size, handling and safety, but recurring dysfunction (kinking or occlusion),
Autor:
Joanna Hummer, Thomas Augustin, Reingard Raml, Simon Schwingenschuh, Thomas Birngruber, Gerd Schwagerle, Frank Sinner, Beate Boulgaropoulos
Publikováno v:
Biomedical physicsengineering express. 6(6)
Objective: To implement OFM-recirculation and OFM-suction capable of direct and absolute in-vivo quantification of albumin in the ISF of pigs. Approach: OFM-recirculation and OFM-suction were used to collect ISF in-vivo in pigs and lymph was collecte
Autor:
Thomas Birngruber, Lars-Peter Kamolz, Christoph Magnes, Dagmar Kolb, Elisabeth Hofmann, Petra Kotzbeck, Eva-Maria Prugger, Selma Mautner, Simon Schwingenschuh, Anita Eberl, Hanna Luze, Julia Fink
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Burn injuries initiate numerous processes such as heat shock response, inflammation and tissue regeneration. Reliable burn models are needed to elucidate the exact sequence of local events to be able to better predict when local inflammation triggers
Autor:
Beate Boulgaropoulos, Simon Schwingenschuh, Katrin I. Tiffner, Elena Rantou, Sam G. Raney, Manfred Bodenlenz, Thomas Birngruber, Frank Sinner, Thomas Augustin
Publikováno v:
Pharmaceutical Research
Purpose Dermal open flow microperfusion (dOFM) has previously demonstrated its utility to assess the bioequivalence (BE) of topical drug products in a clinical study. We aimed to characterize the sources of variability in the dermal pharmacokinetic d
Autor:
Ørjan G. Martinsen, Thomas Augustin, Reingard Raml, Katrin I. Tiffner, Christian Hoefferer, Frank Sinner, Simon Schwingenschuh, E.-C. Prandl, Beate Boulgaropoulos, Christian Dragatin, Hermann Scharfetter, Martin Hajnsek
Publikováno v:
Physiological Measurement. 38:N138-N150
Objective: Pharmacokinetic and pharmacodynamic studies of topically applied drugs are commonly performed by sampling of interstitial fluid with dermal open flow microperfusion and subsequent analysis of the samples. However, the reliability of result
Autor:
Florian Gruber, Dietmar Pum, Lucia Terlecki-Zaniewicz, Michael Mildner, Markus Schosserer, Regina Weinmüllner, Thomas Birngruber, Ingo Lämmermann, Katrin Weiß, Tonja Grillenberger, Eva Stoger, Frédérique Morizot, Elsa Arcalis, Johannes Grillari, Jennifer Schwestka, Thomas Heuser, Erwin Tschachler, Simon Schwingenschuh, Madhusudhan Reddy Bobbili, Ida Perrotta, Vera Pils, Marlene Brandstetter
Publikováno v:
Journal of Investigative Dermatology. 139:2425-2436.e5
Extracellular vesicles (EVs) and their miRNA cargo are intercellular communicators transmitting their pleiotropic messages between different cell types, tissues, and body fluids. Recently, they have been reported to contribute to skin homeostasis and
Autor:
Hermann Scharfetter, Reingard Raml, Frank Sinner, Anton Mautner, Katrin I. Tiffner, Manfred Bodenlenz, Martin Hajnsek, Christian Dragatin, Simon Schwingenschuh, Ørjan G. Martinsen
Publikováno v:
Biomedizinische Technik. Biomedical engineering. 58
Open flow microperfusion can be used to assess the amount of a topically applied drug directly in the skin. Large intra- and interindividual differences in skin proper- ties can lead to biased results. In this study we propose a method based on skin