Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Simon S Gao"'
Autor:
Sehyun Kim, Amy Stockwell, Han Qin, Simon S Gao, Meredith Sagolla, Ivaylo Stoilov, Arthur Wuster, Phillip Lai, Brian L Yaspan, Marion Jeanne
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0280484 (2023)
BackgroundThe basis of Age-related macular degeneration (AMD) genetic risk has been well documented; however, few studies have looked at genetic biomarkers of disease progression or treatment response within advanced AMD patients. Here we report the
Externí odkaz:
https://doaj.org/article/a104a72d384b445883c61de824b7656d
Publikováno v:
Taiwan Journal of Ophthalmology, Vol 7, Iss 3, Pp 115-129 (2017)
Optical coherence tomography angiography (OCTA) is a functional extension of OCT that provides information on retinal and choroidal circulations without the need for dye injections. With the recent development of high-speed OCT systems and efficient
Externí odkaz:
https://doaj.org/article/1bbd73d9ba1f406491f09ca60a62cfe5
Autor:
Yalda Moayedi, Martin L Basch, Natasha L Pacheco, Simon S Gao, Rosalie Wang, Wilbur Harrison, Ningna Xiao, John S Oghalai, Paul A Overbeek, Graeme Mardon, Andrew K Groves
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004055 (2014)
The Notch signaling pathway is thought to regulate multiple stages of inner ear development. Mutations in the Notch signaling pathway cause disruptions in the number and arrangement of hair cells and supporting cells in sensory regions of the ear. In
Externí odkaz:
https://doaj.org/article/2280be277ac146019ba8888a9e473d2a
Autor:
Anping Xia, Yohan Song, Rosalie Wang, Simon S Gao, Will Clifton, Patrick Raphael, Sung-il Chao, Fred A Pereira, Andrew K Groves, John S Oghalai
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82602 (2013)
The outer hair cell (OHC) motor protein prestin is necessary for electromotility, which drives cochlear amplification and produces exquisitely sharp frequency tuning. Tecta(C1509G) transgenic mice have hearing loss, and surprisingly have increased OH
Externí odkaz:
https://doaj.org/article/77f7899eb22d440b86876df874f1f522
Autor:
Frank J Probst, Rebecca R Corrigan, Daniela Del Gaudio, Andrew P Salinger, Isabel Lorenzo, Simon S Gao, Ilene Chiu, Anping Xia, John S Oghalai, Monica J Justice
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80408 (2013)
The study of mouse hearing impairment mutants has led to the identification of a number of human hearing impairment genes and has greatly furthered our understanding of the physiology of hearing. The novel mouse mutant neurological/sensory 5 (nse5) d
Externí odkaz:
https://doaj.org/article/cf3a1dbd43a144ffa7651cc5a3fab92d
Autor:
Sung-Il Cho, Simon S Gao, Anping Xia, Rosalie Wang, Felipe T Salles, Patrick D Raphael, Homer Abaya, Jacqueline Wachtel, Jongmin Baek, David Jacobs, Matthew N Rasband, John S Oghalai
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67618 (2013)
Given the frequent use of improvised explosive devices (IEDs) around the world, the study of traumatic blast injuries is of increasing interest. The ear is the most common organ affected by blast injury because it is the body's most sensitive pressur
Externí odkaz:
https://doaj.org/article/8bc4fc93b99a4dc19cada0c32fffd07a
Autor:
Phyllis Chan, Han Ting Ding, Bianca M. Liederer, Jialin Mao, Paula Belloni, Liuxi Chen, Simon S. Gao, Victory Joseph, Xiaoying Yang, Joseph S. Lin, Mayur S. Mitra, Wendy S. Putnam, Angelica Quartino, Rebecca N. Bauer, Lin Pan
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1945-1954 (2021)
Abstract GDC‐0334 is a novel small molecule inhibitor of transient receptor potential cation channel member A1 (TRPA1), a promising therapeutic target for many nervous system and respiratory diseases. The pharmacokinetic (PK) profile and pharmacody
Externí odkaz:
https://doaj.org/article/38338915571446a38eeb11b03b47d34b
Autor:
Neha, Anegondi, Simon S, Gao, Verena, Steffen, Richard F, Spaide, SriniVas R, Sadda, Frank G, Holz, Christina, Rabe, Lee, Honigberg, Elizabeth M, Newton, Julia, Cluceru, Michael G, Kawczynski, Thomas, Bengtsson, Daniela, Ferrara, Qi, Yang
Publikováno v:
Ophthalmology Retina. 7:243-252
To develop deep learning models for annualized geographic atrophy (GA) growth rate prediction using fundus autofluorescence (FAF) images and spectral-domain OCT volumes from baseline visits, which can be used for prognostic covariate adjustment to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388c96da0a556148af7955c3ccaeab91
https://doi.org/10.1016/j.oret.2022.08.018
https://doi.org/10.1016/j.oret.2022.08.018
Autor:
Han Ting Ding, Wendy S. Putnam, Simon S. Gao, Joseph Lin, Bianca M. Liederer, Jialin Mao, Angelica Quartino, Victory Joseph, Xiaoying Yang, Liuxi Chen, Paula Belloni, Phyllis Chan, Rebecca N. Bauer, Mayur S. Mitra, Lin Pan
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1945-1954 (2021)
Clinical and Translational Science
Clinical and Translational Science
GDC‐0334 is a novel small molecule inhibitor of transient receptor potential cation channel member A1 (TRPA1), a promising therapeutic target for many nervous system and respiratory diseases. The pharmacokinetic (PK) profile and pharmacodynamic (PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14caea2d2691c3e776c7ba0522c5ea6
https://doaj.org/article/38338915571446a38eeb11b03b47d34b
https://doaj.org/article/38338915571446a38eeb11b03b47d34b
Autor:
Sehyun Kim, Amy Stockwell, Han Qin, Simon S. Gao, Meredith Sagolla, Ivaylo Stoilov, Arthur Wuster, Phillip Lai, Brian L. Yaspan, Marion Jeanne
BackgroundThe basis of Age-related macular degeneration (AMD) genetic risk has been well documented; however, few studies have looked at genetic biomarkers of disease progression or treatment response within advanced AMD patients. Here we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce118c975d914ac90bde4817168fe4b
https://doi.org/10.1101/2022.06.22.497149
https://doi.org/10.1101/2022.06.22.497149
