Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Simon S, Gao"'
Autor:
Heming Yao, PhD, Zhichao Wu, BAppSc(Optom), PhD, Simon S. Gao, PhD, Robyn H. Guymer, MBBS, PhD, Verena Steffen, MSc, Hao Chen, PhD, Mohsen Hejrati, PhD, Miao Zhang, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 3, Pp 100428- (2024)
Purpose: Nascent geographic atrophy (nGA) refers to specific features seen on OCT B-scans, which are strongly associated with the future development of geographic atrophy (GA). This study sought to develop a deep learning model to screen OCT B-scans
Externí odkaz:
https://doaj.org/article/2923b293db234d3684c1e211097b8e74
Autor:
Dolly S. Chang, MD, PhD, Natalia F. Callaway, MD, MS, Verena Steffen, MSc, Karl Csaky, MD, PhD, Robyn H. Guymer, MBBS, PhD, David G. Birch, PhD, Praveen J. Patel, MD, Michael Ip, MD, Simon S. Gao, PhD, Jayla Briggs, BS, Lee Honigberg, PhD, Phillip Lai, MD, Daniela Ferrara, MD, PhD, Yasir J. Sepah, MBBS
Publikováno v:
Ophthalmology Science, Vol 4, Iss 1, Pp 100351- (2024)
Purpose: To assess different microperimetry (MP) macular sensitivity outcome measures capturing functional deterioration in eyes with geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Design: Patients were included from 2 i
Externí odkaz:
https://doaj.org/article/4cac05321aed4ed8bfcbc006faad2bbe
Autor:
Sehyun Kim, Amy Stockwell, Han Qin, Simon S Gao, Meredith Sagolla, Ivaylo Stoilov, Arthur Wuster, Phillip Lai, Brian L Yaspan, Marion Jeanne
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0280484 (2023)
BackgroundThe basis of Age-related macular degeneration (AMD) genetic risk has been well documented; however, few studies have looked at genetic biomarkers of disease progression or treatment response within advanced AMD patients. Here we report the
Externí odkaz:
https://doaj.org/article/a104a72d384b445883c61de824b7656d
Autor:
Phyllis Chan, Han Ting Ding, Bianca M. Liederer, Jialin Mao, Paula Belloni, Liuxi Chen, Simon S. Gao, Victory Joseph, Xiaoying Yang, Joseph S. Lin, Mayur S. Mitra, Wendy S. Putnam, Angelica Quartino, Rebecca N. Bauer, Lin Pan
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1945-1954 (2021)
Abstract GDC‐0334 is a novel small molecule inhibitor of transient receptor potential cation channel member A1 (TRPA1), a promising therapeutic target for many nervous system and respiratory diseases. The pharmacokinetic (PK) profile and pharmacody
Externí odkaz:
https://doaj.org/article/38338915571446a38eeb11b03b47d34b
Autor:
Neha, Anegondi, Simon S, Gao, Verena, Steffen, Richard F, Spaide, SriniVas R, Sadda, Frank G, Holz, Christina, Rabe, Lee, Honigberg, Elizabeth M, Newton, Julia, Cluceru, Michael G, Kawczynski, Thomas, Bengtsson, Daniela, Ferrara, Qi, Yang
Publikováno v:
Ophthalmology Retina. 7:243-252
To develop deep learning models for annualized geographic atrophy (GA) growth rate prediction using fundus autofluorescence (FAF) images and spectral-domain OCT volumes from baseline visits, which can be used for prognostic covariate adjustment to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388c96da0a556148af7955c3ccaeab91
https://doi.org/10.1016/j.oret.2022.08.018
https://doi.org/10.1016/j.oret.2022.08.018
Publikováno v:
Taiwan Journal of Ophthalmology, Vol 7, Iss 3, Pp 115-129 (2017)
Optical coherence tomography angiography (OCTA) is a functional extension of OCT that provides information on retinal and choroidal circulations without the need for dye injections. With the recent development of high-speed OCT systems and efficient
Externí odkaz:
https://doaj.org/article/1bbd73d9ba1f406491f09ca60a62cfe5
Autor:
Han Ting Ding, Wendy S. Putnam, Simon S. Gao, Joseph Lin, Bianca M. Liederer, Jialin Mao, Angelica Quartino, Victory Joseph, Xiaoying Yang, Liuxi Chen, Paula Belloni, Phyllis Chan, Rebecca N. Bauer, Mayur S. Mitra, Lin Pan
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1945-1954 (2021)
Clinical and Translational Science
Clinical and Translational Science
GDC‐0334 is a novel small molecule inhibitor of transient receptor potential cation channel member A1 (TRPA1), a promising therapeutic target for many nervous system and respiratory diseases. The pharmacokinetic (PK) profile and pharmacodynamic (PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14caea2d2691c3e776c7ba0522c5ea6
https://doaj.org/article/38338915571446a38eeb11b03b47d34b
https://doaj.org/article/38338915571446a38eeb11b03b47d34b
Autor:
Sehyun Kim, Amy Stockwell, Han Qin, Simon S. Gao, Meredith Sagolla, Ivaylo Stoilov, Arthur Wuster, Phillip Lai, Brian L. Yaspan, Marion Jeanne
BackgroundThe basis of Age-related macular degeneration (AMD) genetic risk has been well documented; however, few studies have looked at genetic biomarkers of disease progression or treatment response within advanced AMD patients. Here we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce118c975d914ac90bde4817168fe4b
https://doi.org/10.1101/2022.06.22.497149
https://doi.org/10.1101/2022.06.22.497149
Autor:
Steffen Schmitz-Valckenberg, Marlene Saßmannshausen, Sarah Thiele, Simon S. Gao, Frank G. Holz, Martina Braun, Hao Chen, Daniela Ferrara, Lee Honigberg, Verena Steffen
Publikováno v:
Ophthalmologica. 244:523-534
Introduction: This retrospective analysis assessed geographic atrophy (GA) progression in fellow eyes from the Proxima B trial intermediate age-related macular degeneration (iAMD) subcohort using high-resolution multimodal imaging anchored on optical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7342d28858dcbb278ccee0cb7f25688e
https://doi.org/10.1159/000517881
https://doi.org/10.1159/000517881
Autor:
Cory Thrasher, Simon S. Gao, Joseph Lin, Nand Singh, Robby M. Weimer, Rebecca N. Bauer, Wiebke Theess, Justin Elstrott, Victory Joseph, Xiaoying Yang
Publikováno v:
British Journal of Clinical Pharmacology. 87:129-139
Background and purpose Develop a translational assay of Transient Receptor Potential Ankyrin 1 (TRPA1) activity for use as a preclinical and clinical biomarker. Experimental approach Allyl isothiocyanate (AITC), capsaicin or citric acid were applied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca22ecd980ad287b818464d41a2bbef
https://doi.org/10.1111/bcp.14370
https://doi.org/10.1111/bcp.14370