Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Simon Rothberg"'
Autor:
Simon Rothberg, Benjamin C Arp
Publikováno v:
Journal of Investigative Dermatology. 64:245-249
Epidermal aqueous extracts, previously assayed by their inhibition of epidermal mitosis, were assayed by their inhibition of 3H-thymidine incorporation into epidermal, dermal, and total skin DNA. Several experimental sources for epidermal extract, ne
Autor:
Ralph S. Jessup, Simon Rothberg
Publikováno v:
Industrial & Engineering Chemistry. 43:981-985
Autor:
Simon Rothberg
Publikováno v:
Journal of Investigative Dermatology. 43:151-157
The protective nature of the human epidermis is made possible by the layered structure formed at the topmost levels of the epidermis. This structure is the end product of the metabolic activity of epidermal cells. The major component of this layered
Autor:
Robert G. Crounse, Simon Rothberg
Publikováno v:
Journal of Investigative Dermatology. 35(2):107-111
Arginase, an enzyme which catalyses the cleavage of arginine to ornithine and urea, is widely distributed in nature (1). It is present in a variety of mammalian tissues including the liver, kidney, testes, breast (1, 2), and some animal tumors (3). M
Publikováno v:
Journal of Biological Chemistry. 229:905-920
Publikováno v:
Journal of Investigative Dermatology. 44:320-325
The postulate that keratinous protein in psoriatic epidermis is abnormal has been the subject of much discussion (1, 2). At present, there is no direct evidence that the disturbed keratinization in psoriasis results in the synthesis of an abnormal pr
Autor:
Daniel Steinberg, Simon Rothberg
Publikováno v:
Journal of the American Chemical Society. 79:3274-3278
Autor:
Simon Rothberg
Publikováno v:
Annals of the New York Academy of Sciences. 73:1004-1012
Publikováno v:
Journal of Investigative Dermatology. 37(6):497-505
A continual synthesis of keratin by the human epidermis is necessary to provide the protein found in the continuously renewed outermost layer, the stratum corneum. Normal formation of the stratum corneum in a lesion of psoriasis is incomplete, althou
Autor:
Gertrude D. Axilrod, Simon Rothberg
Publikováno v:
Science. 156:90-93
Insoluble epidermal proteins (possibly keratin), previously considered inert to enzyme action, were solubilized by either trypsin or chymotrypsin. Cleavage of the disulfide bonds prior to enzymatic action is not necessary. In addition, the enzymatic