Rare diseases: why is a rapid referral to an expert center so important?

Autor: Tina Willmen, Lukas Willmen, Anne Pankow, Simon Ronicke, Heinz Gabriel, Annette Doris Wagner

Publikováno v: BMC Health Services Research, Vol 23, Iss 1, Pp 1-8 (2023)

Abstract Background Patients with rare diseases usually go through years of diagnostic odysseys. The large number of rare diseases and the associated lack of expertise pose a major challenge to physicians. There are few physicians dealing with patien

Externí odkaz: https://doaj.org/article/64826be8022d42ac9bc828a304433f33

Health economic benefits through the use of diagnostic support systems and expert knowledge

Autor: Tina Willmen, Lukas Völkel, Simon Ronicke, Martin C. Hirsch, Jessica Kaufeld, Reinhard P. Rychlik, Annette D. Wagner

Publikováno v: BMC Health Services Research, Vol 21, Iss 1, Pp 1-11 (2021)

Abstract Background Rare diseases are difficult to diagnose. Due to their rarity, heterogeneity, and variability, rare diseases often result not only in extensive diagnostic tests and imaging studies, but also in unnecessary repetitions of examinatio

Externí odkaz: https://doaj.org/article/16bacde1aae14561b0b1ec9a5e412c2e

Poor Outcomes in Patients With Transplant Glomerulopathy Independent of Banff Categorization or Therapeutic Interventions

Autor: Kaiyin Wu, Danilo Schmidt, Covadonga López del Moral, Bilgin Osmanodja, Nils Lachmann, Fabian Halleck, Mira Choi, Friederike Bachmann, Simon Ronicke, Wiebke Duettmann, Marcel Naik, Eva Schrezenmeier, Birgit Rudolph, Klemens Budde

Publikováno v: Frontiers in Medicine, Vol 9 (2022)

BackgroundTransplant glomerulopathy (TG) may indicate different disease entities including chronic AMR (antibody-mediated rejection). However, AMR criteria have been frequently changed, and long-term outcomes of allografts with AMR and TG according t

Externí odkaz: https://doaj.org/article/20262ecd9f70436abe164bd3a87e9312

Can a decision support system accelerate rare disease diagnosis? Evaluating the potential impact of Ada DX in a retrospective study

Autor: Simon Ronicke, Martin C. Hirsch, Ewelina Türk, Katharina Larionov, Daphne Tientcheu, Annette D. Wagner

Publikováno v: Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-12 (2019)

Abstract Background Rare disease diagnosis is often delayed by years. A primary factor for this delay is a lack of knowledge and awareness regarding rare diseases. Probabilistic diagnostic decision support systems (DDSSs) have the potential to accele

Externí odkaz: https://doaj.org/article/6e203414afb64eccab18b79369bbc544

Poor Long-Term Renal Allograft Survival in Patients with Chronic Antibody-Mediated Rejection, Irrespective of Treatment—A Single Center Retrospective Study

Autor: Kaiyin Wu, Danilo Schmidt, Covadonga López del Moral, Bilgin Osmanodja, Nils Lachmann, Qiang Zhang, Fabian Halleck, Mira Choi, Friederike Bachmann, Simon Ronicke, Wiebke Duettmann, Marcel G. Naik, Eva Schrezenmeier, Birgit Rudolph, Klemens Budde

Publikováno v: Journal of Clinical Medicine, Vol 11, Iss 199, p 199 (2022)
Journal of Clinical Medicine; Volume 11; Issue 1; Pages: 199
Journal of Clinical Medicine

The Banff 2017 report permits the diagnosis of pure chronic antibody-mediated rejection (cAMR) in absence of microcirculation inflammation. We retrospectively investigated renal allograft function and long-term outcomes of 67 patients with cAMR, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27651394ebd21f22f54a78220b3010dd
https://www.mdpi.com/2077-0383/11/1/199