Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Simon Roman-Goldstein"'
Autor:
Robert A. KrolI, Michael A. Pagel, Leslie L. Muldoon, Simon Roman-Goldstein, Edward A. Neuwelt
Publikováno v:
Neurosurgery. 38:746-754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45839d885618442dbc6440163b36ea23
https://doi.org/10.1227/00006123-199604000-00024
https://doi.org/10.1227/00006123-199604000-00024
Autor:
Michael A. Pagel, Robert A. Kroll, Edward A. Neuwelt, Simon Roman-Goldstein, Leslie L. Muldoon
Publikováno v:
Neurosurgery. :746-754
The volume of distribution in tissue (Vt) that can be achieved by direct interstitial infusion of therapeutic agents into brain is limited. The maintenance of a pressure gradient during interstitial infusion to establish fluid convection has been sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a094e56cc83db0a96538969a2d9d5ca0
https://doi.org/10.1097/00006123-199604000-00024
https://doi.org/10.1097/00006123-199604000-00024
Publikováno v:
Pediatric Neurosurgery. 22:20-28
We reviewed 27 patients with congenital anomalies of the sacral spine. There were 16 males and 11 females with a mean follow-up of 81.1 months (range 8-211 months). Fifteen patients had sacral agenesis and 12 had sacral dysgenesis. Fifteen patients h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fa2ca6fe657c2f985af6cfd01dfbce
https://doi.org/10.1159/000121295
https://doi.org/10.1159/000121295
Autor:
Jerzy Szumowski, Eva Marie Shannon, Edward A. Neuwelt, Gajanan Nilaver, Michael A. Pagel, Laura G. Remsen, Simon Roman-Goldstein, Leslie L. Muldoon, Ralph Weissleder, Robert A. Kroll, Christopher I. McCormick, Russell S. Jones
Publikováno v:
Neurosurgery. 34:777-784
Delivery of viral particles to the brain is limited by the volume of distribution that can be obtained. Additionally, there is currently no way to non-invasively monitor the distribution of virus following delivery to the central nervous system (CNS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a6359080a067258f4988eaefb3ec7f
https://doi.org/10.1227/00006123-199404000-00048
https://doi.org/10.1227/00006123-199404000-00048
Autor:
Bruce Dana, Suellen A. Dahlborg, Edward A. Neuwelt, John R. Crossen, Simon Roman-Goldstein, Fred L. Ramsey, David L. Goldman, Rita M. Braziel
Publikováno v:
Journal of Clinical Oncology. 9:1580-1590
Combination chemotherapy with or without radiotherapy has had only modest efficacy in the treatment of primary CNS lymphoma. Median survival of these patients, treated primarily with radiotherapy, is 13 months; 5-year survival is less than 5%. Thirty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3782624d9401da96fe7bd4590ba8e51
https://doi.org/10.1200/jco.1991.9.9.1580
https://doi.org/10.1200/jco.1991.9.9.1580
Autor:
Edward A. Neuwelt, Michael A. Pagel, Robert A. Kroll, Simon Roman-Goldstein, Leslie L. Muldoon
Publikováno v:
Gene Therapy for Neurological Disorders and Brain Tumors ISBN: 9781475753141
Delivery is a major issue in the treatment of neurological disease and tumors affecting the central nervous system (CNS). Delivery of genetic material to target cells at the molecular level has been reviewed elsewhere (please see the preceding chapte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f634c55e17c2be5830b7753391fb230
https://doi.org/10.1385/0-89603-507-7:295
https://doi.org/10.1385/0-89603-507-7:295
Publikováno v:
Neurosurgery. 43(3)
Objective and importance Primary central nervous system lymphoma is a disease with increasing incidence. Atypical presentations are becoming more frequent. Clinical presentation Three patients bearing cavernous sinus lesions presented initially with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ab4fcefe114dea831d64e3df374ab6
https://pubmed.ncbi.nlm.nih.gov/9733317
https://pubmed.ncbi.nlm.nih.gov/9733317
Autor:
Raymond Garcia, Laura G. Remsen, Michele Mass, Harper D. Pearse, Gary Sexton, Simon Roman-Goldstein, Christopher I. McCormick, Edward A. Neuwelt
Publikováno v:
Neurosurgery. 40(5)
OBJECTIVE: The goal was to evaluate, at 1 year, 75 Long-Evans rats for survival rates and toxicity associated with the sequencing of cranial irradiation and enhanced chemotherapy delivery. METHODS: Seventy-five Long-Evans rats were randomized into fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7d093b5f0e9a5520755096598bed8e
https://pubmed.ncbi.nlm.nih.gov/9149262
https://pubmed.ncbi.nlm.nih.gov/9149262
Autor:
Robert E. Brummett, Paul Williams, Mara Tableman, Bruce Dana, Simon Roman-Goldstein, W. D. Henner, Edward A. Neuwelt, Suellen A. Dahlborg
Publikováno v:
Neurosurgery. 37(1)
CARBOPLATIN AND ETOPOSIDE have been investigated in preclinical studies and a limited toxicity study in 13 patients; these studies have established carboplatin and etoposide as a tolerable combination when administered with blood-brain barrier disrup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7f716f80e0051c13397bcbf1f5602c
https://pubmed.ncbi.nlm.nih.gov/8587686
https://pubmed.ncbi.nlm.nih.gov/8587686
Autor:
Fred L. Ramsey, Peggy A. Barnett, Jerzy Szumowski, Eva Marie Shannon, Christopher I. McCormick, Michele Mass, Edward A. Neuwelt, Simon Roman-Goldstein
Publikováno v:
Journal of computer assisted tomography. 18(5)
Objective This experiment was done to evaluate the gross neurotoxicity of intravenous Gd-DTPA administered in conjunction with osmotic blood-brain barrier (BBB) disruption and to image a human small cell lung carcinoma intracerebral tumor xenograft b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e761ab68c97415e43e547879ed1553
https://pubmed.ncbi.nlm.nih.gov/8089321
https://pubmed.ncbi.nlm.nih.gov/8089321