Výsledky vyhledávání - "Simon Rohrbach"

Digitization and validation of a chemical synthesis literature database in the ChemPU

Autor: Simon Rohrbach, Mindaugas Šiaučiulis, Greig Chisholm, Petrisor-Alin Pirvan, Michael Saleeb, S. Hessam M. Mehr, Ekaterina Trushina, Artem I. Leonov, Graham Keenan, Aamir Khan, Alexander Hammer, Leroy Cronin

Publikováno v: Science (New York, N.Y.). 377(6602)

Despite huge potential, automation of synthetic chemistry has only made incremental progress over the past few decades. We present an automatically executable chemical reaction database of 100 molecules representative of the range of reactions found

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc3949eb0d87b2807c4e707a7cd8657
https://pubmed.ncbi.nlm.nih.gov/35857541

Zobrazit plný text záznamu

Plný text ve formátu HTML

Convergence of multiple synthetic paradigms in a universally programmable chemical synthesis machine

Autor: Jakob Wolf, Stefanie Krambeck, Simon Rohrbach, Alexander J. S. Hammer, Leroy Cronin, Greig Chisholm, Davide Angelone, Sergey S. Zalesskiy, Jarosław M. Granda

Publikováno v: Nature Chemistry. 13:63-69

Although the automatic synthesis of molecules has been established, each reaction class uses bespoke hardware. This means that the connection of multi-step syntheses in a single machine to run many different protocols and reactions is not possible, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570b6d0d0f6b0fe0717fba3ff4fc39b7
https://doi.org/10.1038/s41557-020-00596-9

Zobrazit plný text záznamu

Computational study on the boundary between the concerted and stepwise mechanism of bimolecular SNAr reactions

Autor: John A. Murphy, Tell Tuttle, Simon Rohrbach

The text-book mechanism of bimolecular nucleophilic aromatic substitutions (SNAr) reactions is a stepwise process that proceeds via a so-called Meisenheimer intermediate. Only recently the alternative, concerted version of this mechanism has gained a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1928ba931e028410a74715f5e0c63b49
https://strathprints.strath.ac.uk/73526/7/Rohrbach_etal_JACS_2020_Computational_study_on_the_boundary_between_the_concerted_and_stepwise.pdf

Zobrazit plný text záznamu

Computational Study on the Boundary Between the Concerted and Stepwise Mechanism of Bimolecular S

Autor: Simon, Rohrbach, John A, Murphy, Tell, Tuttle

Publikováno v: Journal of the American Chemical Society

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b6b2ccc02e3d82767d6438df73b99ee
https://pubmed.ncbi.nlm.nih.gov/32786763

Zobrazit plný text záznamu

N‐Silylation of Amines Mediated by Et 3 SiH/KO t Bu

Autor: Fabrizio Palumbo, Tell Tuttle, John A. Murphy, Simon Rohrbach

Publikováno v: Helvetica Chimica Acta. 102

Silylation of primary and secondary amines is reported, using triethylsilane as the silylating reagent in the presence of potassium tert-butoxide (KOtBu). The reaction proceeds well in the presence of 0.2 equiv of KOtBu. In competition experiments, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5602c3f69115597c1f89b5ed03ba022d
https://doi.org/10.1002/hlca.201900235

Zobrazit plný text záznamu

Konzertierte nukleophile aromatische Substitutionen

Autor: Tell Tuttle, Shunsuke Chiba, Simon Rohrbach, Jia Hao Pang, Darren L. Poole, John A. Murphy, Andrew Smith

Jüngste Entwicklungen in der experimentellen und theoretischen Chemie haben zur Identifizierung einer schnell wachsenden Klasse von nukleophilen aromatischen Substitutionsreaktionen geführt, die einem konzertierten Mechanismus (cSNAr) folgen, und n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51c869de1925b141ce87938c213935b
https://strathprints.strath.ac.uk/78957/1/Rohrbach_etal_AC_2019_Konzertierte_nukleophile_aromatische_substitutionen.pdf

Zobrazit plný text záznamu

Concerted nucleophilic aromatic substitution reactions

Autor: Andrew J. Smith, Jia Hao Pang, John A. Murphy, Darren L. Poole, Shunsuke Chiba, Tell Tuttle, Simon Rohrbach

Publikováno v: Angewandte Chemie (International Ed. in English)

Recent developments in experimental and computational chemistry have identified a rapidly growing class of nucleophilic aromatic substitutions that proceed by concerted (cSNAr) rather than classical, two‐step, SNAr mechanisms. Whereas traditional S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc7fdb8dcde51452c8db5ef0012abdb
https://strathprints.strath.ac.uk/67652/7/Rohrbach_etal_ACIE_2019_Concerted_nucleophilic_aromatic_substitution_reactions.pdf

Zobrazit plný text záznamu

Cyclopropanation of Terminal Alkenes via Sequential Atom Transfer Radical Addition – 1,3-Elimination

Autor: Philippe Renaud, Weronika Michalska, Nicholas D. C. Tappin, Simon Rohrbach

An operationally simple protocol to affect an atom transfer radical addition (ATRA) of commercially available ICH2Bpin to terminal alkenes has been developed. The intermediate iodide can be transformed in a one-pot process into the corresponding cycl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7c194dbd23d29ec78f2f1effbfd97c
https://doi.org/10.26434/chemrxiv.8325251.v1

Zobrazit plný text záznamu

Neutral Organic Super Electron Donors Made Catalytic

Autor: John A. Murphy, Tell Tuttle, Simon Rohrbach, Rushabh S. Shah

Publikováno v: Angewandte Chemie (International ed. in English). 58(33)

Neutral organic super electron donors (SEDs) display impressive reducing power but, until now, it has not been possible to use them catalytically in radical chain reactions. This is because, following electron transfer, these donors form persistent r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff27ec08c9804aa4b3e70aaca7a03128
https://pubmed.ncbi.nlm.nih.gov/31609546

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání