Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Simon R.N. Sauter"'
Autor:
Kathrin Ullrich, Stephan Diekmann, Gerald P. Gellermann, Christiane Unger, Marcus Fändrich, Simon R.N. Sauter
Publikováno v:
Journal of Neuroscience Research. 85:2037-2044
Amyloid diseases are characterized by the formation of insoluble amyloid fibrils from previously soluble polypeptides. In Alzheimer's disease (AD), amyloid fibrils, formed from β-amyloid peptides, are deposited as extracellular amyloid plaques only
Autor:
Uwe Horn, Michael Decker, Astrid Tannert, Simon R.N. Sauter, Kathrin Ullrich, Gerald P. Gellermann, Marcus Fändrich, Peter Hortschansky, Christiane Unger, Gernot Habicht, Ute Möllmann, Jochen Lehmann
Publikováno v:
Journal of Molecular Biology. 360:251-257
The cerebral deposition of Aβ-peptide as amyloid fibrils and plaques represents a hallmark characteristic of Alzheimer's disease (AD). AD plaques are defined by their green birefringence after Congo red staining, their spherulite-like superstructure