Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Simon R. Picker"'
Autor:
Amy R Fairchild, Jessica C Pickles, François Guillemot, Martin Tisdall, Darren Hargrave, Dale Moulding, Simon M. L. Paine, Fatma Scerif, SA Yasin, Thomas S. Jacques, Simon R. Picker, Aimee Avery, Thomas J Stone, Yao-Feng Li, J. Helen Cross, Alex Virasami, William Harkness
Publikováno v:
Neuropathology and Applied Neurobiology. 47:781-795
Aims We understand little of the pathogenesis of developmental cortical lesions, because we understand little of the diversity of the cell types that contribute to the diseases or how those cells interact. We tested the hypothesis that cellular diver
Autor:
Khadijah Miller, SA Yasin, Kate Latak, Oliver Campos, Martin Smith, Maria Thom, Thomas S. Jacques, Brian Harding, Anita Ganapathi, J. Helen Cross, Glenn Anderson, Simon R. Picker, Francesca Becherini, William Harkness, Nelly Bier
Publikováno v:
Acta Neuropathologica. 120:85-96
Neural stem cells are present in the human post-natal brain and are important in the development of brain tumours. However, their contribution to non-neoplastic human disease is less clear. We have tested the hypothesis that malformations of cortical
Autor:
Antony Michalski, Ruth G. Tatevossian, Kim Phipps, Tim Forshew, Simon R. Picker, Thomas S. Jacques, Andrew R. J. Lawson, Denise Sheer
Publikováno v:
Acta Neuropathologica. 120:271-273
Brain tumours are the most common solid tumour in children and are the primary cause of cancer-related death in children and young adults [4, 6]. The most prevalent childhood brain tumours are low-grade gliomas, specifically pilocytic astrocytomas (P
Autor:
William Harkness, SA Yasin, Thomas S. Jacques, Glenn Anderson, Mathew Tata, Abu M. Ali, Sarah L. Nicholson, Elizabeth Latimer-Bowman, Simon M. L. Paine, J. Helen Cross, Simon R. Picker
Publikováno v:
Acta neuropathologica. 126(2)
Focal cortical dysplasia (FCD) is a localized malformation of cortical development and is the commonest cause of severe childhood epilepsy in surgical practice. Children with FCD are severely disabled by their epilepsy, presenting with frequent seizu
Autor:
Joelle Tchinda, Angela M. Cáceres, Stephen W. Scherer, Anne C. Stone, Charles Lee, Evan E. Eichler, Junjun Zhang, Sean McGrath, Simon R. Picker, A. John Iafrate, George H. Perry, Chris Tyler-Smith
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(21)
Copy number variation is surprisingly common among humans and can be involved in phenotypic diversity and variable susceptibility to complex diseases, but little is known of the extent of copy number variation in nonhuman primates. We have used two a
Autor:
Muhammad A. Mumin, Denise Sheer, Kim Phipps, Sheena N. Patel, Andrew R. J. Lawson, Simon R. Picker, Thomas S. Jacques, Antony Michalski, Gabriel T. Doctor, Jennie N. Jeyapalan, Tania A. Jones, Ruth G. Tatevossian, Tim Forshew
Publikováno v:
Acta Neuropathologica Communications
Introduction Pilocytic astrocytomas are slow-growing tumors that usually occur in the cerebellum or in the midline along the hypothalamic/optic pathways. The most common genetic alterations in pilocytic astrocytomas activate the ERK/MAPK signal trans