Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Simon R. Johnson"'
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Background Lymphangioleiomyomatosis (LAM) is common in tuberous sclerosis complex (TSC) yet under recognised with management mostly based upon evidence obtained from patients with sporadic LAM. We performed a prospective audit of patients wi
Externí odkaz:
https://doaj.org/article/81ebfc6a88b641acb1299c3726a5b50b
Autor:
Michael A. Portelli, Sangita Bhaker, Vincent Pang, David O. Bates, Simon R. Johnson, Andrew P. Mazar, Dominick Shaw, Christopher Brightling, Ian Sayers
Publikováno v:
Clinical and Translational Allergy, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Background Expression of the urokinase plasminogen activator receptor (uPAR) is elevated in the airway epithelium in asthma; however, the contribution of uPAR to asthma pathogenesis and scope for therapeutic targeting remains unknown. Object
Externí odkaz:
https://doaj.org/article/b98b2138b6a345bba5e4c156f9115f19
Autor:
Maurizio Chioccioli, Subhadeep Roy, Rachel Newell, Linda Pestano, Brent Dickinson, Kevin Rigby, Jose Herazo-Maya, Gisli Jenkins, Steward Ian, Gauri Saini, Simon R. Johnson, Rebecca Braybrooke, Guying Yu, Maor Sauler, Farida Ahangari, Shuizi Ding, Joseph DeIuliis, Nachelle Aurelien, Rusty L. Montgomery, Naftali Kaminski
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104304- (2022)
Summary: Background: MicroRNAs are non-coding RNAs that negatively regulate gene networks. Previously, we reported that systemically delivered miR-29 mimic MRG-201 reduced fibrosis in animal models, supporting the consideration of miR-29-based therap
Externí odkaz:
https://doaj.org/article/0b9f4e10e633477c90233cf6675cf157
Autor:
Cynthia Gonano, Jérôme Pasquier, Cécile Daccord, Simon R. Johnson, Sergio Harari, Violette Leclerc, Lucy Falconer, Eleonora Miano, Jean-François Cordier, Vincent Cottin, Romain Lazor
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-8 (2018)
Abstract Background Pulmonary lymphangioleiomyomatosis (LAM) is a rare disease of women characterized by multiple lung cysts leading to respiratory insufficiency and frequent pneumothorax (PT). Air travel (AT) could increase the risk of PT in LAM thr
Externí odkaz:
https://doaj.org/article/55dff177b7c046f585d83c74b5f46155
Autor:
Nicholas M. P. Annear, Richard E. Appleton, Zahabiyah Bassi, Rupesh Bhatt, Patrick F. Bolton, Pamela Crawford, Alex Crowe, Maureen Tossi, Frances Elmslie, Eric Finlay, Daniel P. Gale, Alex Henderson, Elizabeth A. Jones, Simon R. Johnson, Shelagh Joss, Larissa Kerecuk, Graham Lipkin, Patrick J. Morrison, Finbar J. O'Callaghan, Jill Cadwgan, Albert C. M. Ong, Julian R. Sampson, Charles Shepherd, J. Chris Kingswood
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/416cfa5982e74156bdce76fe0309cc6b
Autor:
Iain Stewart, Joseph Jacob, Peter M. George, Philip L. Molyneaux, Joanna C. Porter, Richard J. Allen, Shahab Aslani, J. Kenneth Baillie, Shaney L. Barratt, Paul Beirne, Stephen M. Bianchi, John F. Blaikley, James D. Chalmers, Rachel C. Chambers, Nazia Chadhuri, Christopher Coleman, Guilhem Collier, Emma K. Denneny, Annemarie Docherty, Omer Elneima, Rachael A. Evans, Laura Fabbri, Michael A. Gibbons, Fergus V. Gleeson, Bibek Gooptu, Neil J. Greening, Beatriz Guillen Guio, Ian P. Hall, Neil A. Hanley, Victoria Harris, Ewen M. Harrison, Melissa Heightman, Toby E. Hillman, Alex Horsley, Linzy Houchen-Wolloff, Ian Jarrold, Simon R. Johnson, Mark G. Jones, Fasihul Khan, Rod Lawson, Olivia Leavy, Nazir Lone, Michael Marks, Hamish McAuley, Puja Mehta, Dhruv Parekh, Karen Piper Hanley, Manuela Platé, John Pearl, Krisnah Poinasamy, Jennifer K. Quint, Betty Raman, Matthew Richardson, Pilar Rivera-Ortega, Laura Saunders, Ruth Saunders, Malcolm G. Semple, Marco Sereno, Aarti Shikotra, A. John Simpson, Amisha Singapuri, David J. F. Smith, Mark Spears, Lisa G. Spencer, Stefan Stanel, David R. Thickett, A. A. Roger Thompson, Mathew Thorpe, Simon L. F. Walsh, Samantha Walker, Nicholas David Weatherley, Mark E. Weeks, Jim M. Wild, Dan G. Wootton, Chris E. Brightling, Ling-Pei Ho, Louise V. Wain, Gisli R. Jenkins
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:693-703
Autor:
Amanda L. Tatler, Christopher J. Philp, Michael R. Hill, Sam Cox, Andrew M. Bullock, Anthony Habgood, Alison John, Robert Middlewick, Katherine E. Stephenson, Amanda T. Goodwin, Charlotte K. Billington, Reuben D. O’Dea, Simon R. Johnson, Bindi S. Brook
Publikováno v:
L284
L271
L271
Airway remodeling occurs in chronic asthma leading to increased airway smooth muscle (ASM) mass and extracellular matrix (ECM) deposition. Although extensively studied in murine airways, studies report only selected larger airways at one time-point m
Publikováno v:
Thorax. 78:61-68
Study questionIn lymphangioleiomyomatosis, airflow obstruction and impairment of gas transfer progress at variable rates and serial lung function is recommended for disease monitoring. As these measurements are variable, recognising subjects needing
Autor:
Bruno Guedes Baldi, Elzbieta Radzikowska, Vincent Cottin, Daniel F. Dilling, Ali Ataya, Carlos Roberto Ribeiro Carvalho, Sergio Harari, Matthew Koslow, Jan C. Grutters, Yoshikazu Inoue, Nishant Gupta, Simon R. Johnson
Publikováno v:
Chest. 161:1589-1593
Autor:
Julian R. Sampson, J. Chris Kingswood, Anne E. Tattersfield, Justin J. Cross, Kate Pointon, Tim Doyle, Christopher J. Howe, Peter C. Watson, Andreas L. Serra, Jane A. Cox, Deborah L. McCartney, Simon R. Johnson, Petrus J. de Vries, D. Mark Davies
Supplementary Tables 1-3 from Sirolimus Therapy for Angiomyolipoma in Tuberous Sclerosis and Sporadic Lymphangioleiomyomatosis: A Phase 2 Trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c366cc4d8df2ef3719d2af4e332f1abb
https://doi.org/10.1158/1078-0432.22441219
https://doi.org/10.1158/1078-0432.22441219