Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Simon Peter Williams"'
Autor:
Shravan Kumar Sriraman, Christopher W. Davies, Herman Gill, James R. Kiefer, Jianping Yin, Annie Ogasawara, Alejandra Urrutia, Vincent Javinal, Zhonghua Lin, Dhaya Seshasayee, Ryan Abraham, Phil Haas, Christopher Koth, Jan Marik, James T. Koerber, Simon Peter Williams
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 50:679-691
Autor:
Simon-Peter Williams, Suzie J. Scales, Jan Marik, Ron Firestein, Dongwei Li, Nidhi Gupta, Jeff N. Tinianow, Alexander N. Vanderbilt, Glenn Pacheco, Annie Ogasawara, Anton G.T. Terwisscha van Scheltinga
Supplementary Figure 1: Serum levels of AMA-MMAE in mice. Supplementary Figure 2: Correlation plot of tumor growth inhibition versus specific tumor uptake. Supplementary Table 1: Overview results. Supplementary Table 2: Tumor growth inhibition study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468bd46c914b424ebc2d10e18892c40f
https://doi.org/10.1158/1535-7163.22508646
https://doi.org/10.1158/1535-7163.22508646
Autor:
Annie, Ogasawara, James R, Kiefer, Herman, Gill, Eugene, Chiang, Shravan, Sriraman, Gregory Z, Ferl, James, Ziai, Sandra Sanabria, Bohorquez, Sebastian, Guelman, Xiangdan, Wang, Jihong, Yang, Minh Michael, Phan, Van, Nguyen, Shan, Chung, Christine, Yu, Jeff, Tinianow, Stijn Jan Hein, Waaijer, Alex, De Crespigny, Jan, Marik, C Andrew, Boswell, Tanja, Zabka, Karin, Staflin, Simon-Peter, Williams
Publikováno v:
European journal of nuclear medicine and molecular imaging. 50(2)
ZED8 is a novel monovalent antibody labeled with zirconium-89 for the molecular imaging of CD8. This work describes nonclinical studies performed in part to provide rationale for and to inform expectations in the early clinical development of ZED8, s
Autor:
Shravan Kumar, Sriraman, Christopher W, Davies, Herman, Gill, James R, Kiefer, Jianping, Yin, Annie, Ogasawara, Alejandra, Urrutia, Vincent, Javinal, Zhonghua, Lin, Dhaya, Seshasayee, Ryan, Abraham, Phil, Haas, Christopher, Koth, Jan, Marik, James T, Koerber, Simon Peter, Williams
Publikováno v:
European journal of nuclear medicine and molecular imaging.
Cancer immunotherapies (CITs) have revolutionized the treatment of certain cancers, but many patients fail to respond or relapse from current therapies, prompting the need for new CIT agents. CD8To this end, we discovered and developed a 13-kDa singl
Autor:
Annie Ogasawara, James R. Kiefer, Herman Gill, Eugene Chiang, Shravan Sriraman, Gregory Z. Ferl, James Ziai, Sandra Sanabria Bohorquez, Sebastian Guelman, Xiangdan Wang, Jihong Yang, Minh Michael Phan, Van Nguyen, Shan Chung, Christine Yu, Jeff Tinianow, Stijn Jan Hein Waaijer, Alex De Crespigny, Jan Marik, C. Andrew Boswell, Tanja Zabka, Karin Staflin, Simon‑Peter Williams
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 50:631-631
Autor:
Alex de Crespigny, Paul E. Christian, Sandra Sanabria Bohorquez, Lance D. Burrell, Andrei Iagaru, Paulo Castaneda, Justin Albiani, Nicholas Sandella, John M. Hoffman, Simon-Peter Williams
Publikováno v:
Journal of Nuclear Medicine Technology. 48:54-57
Objective: To harmonize multicenter 89Zr PET imaging for oncology trials and to evaluate lesion detection. Methods: Seven PET scanners were evaluated using a custom chest oncology phantom with nine spherical lesions, 7-20 mm in diameter. A 4:1 lesion
Autor:
Thomas Bengtsson, Michael Ward, Paul T. Manser, David Alagille, Jan Marik, Geoffrey A. Kerchner, Jeff N. Tinianow, Sandra Sanabria Bohorquez, Herman Gill, Kenneth Marek, Olivier Barret, Simon-Peter Williams, Robby M. Weimer, J Seibyl, Annie Ogasawara, Gai Ayalon, Gilles Tamagnan
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 46:2077-2089
Neurofibrillary tangles (NFTs), consisting of intracellular aggregates of the tau protein, are a pathological hallmark of Alzheimer’s disease (AD). Here we report the identification and initial characterization of Genentech Tau Probe 1 ([18F]GTP1),
Autor:
Isabella de Jong, Herman Gill, Simon-Peter Williams, Jan Marik, Ohad Ilovich, Jian Yin, Jihong Yang, Alexandra Gouasmat, Minh Michael Phan, Richard Seipert, Vincent M. Carroll, Xiangdan Wang, Annie Ogasawara
Publikováno v:
The AAPS Journal. 22
Immuno-PET is a molecular imaging technique utilizing positron emission tomography (PET) to measure the biodistribution of an antibody species labeled with a radioactive isotope. When applied as a clinical imaging technique, an immuno-PET imaging age
Autor:
Herman, Gill, Richard, Seipert, Vincent M, Carroll, Alexandra, Gouasmat, Jian, Yin, Annie, Ogasawara, Isabella, de Jong, Minh Michael, Phan, Xiangdan, Wang, Jihong, Yang, Ohad, Ilovich, Jan, Marik, Simon-Peter, Williams
Publikováno v:
The AAPS journal. 22(2)
Immuno-PET is a molecular imaging technique utilizing positron emission tomography (PET) to measure the biodistribution of an antibody species labeled with a radioactive isotope. When applied as a clinical imaging technique, an immuno-PET imaging age
Autor:
Jan Marik, Alexander N. Vanderbilt, Sharla L. White, Annie Ogasawara, Georgia Hatzivassiliou, Kevin DeMent, Jeff N. Tinianow, Tang Tang, Simon-Peter Williams, Wendy Sandoval, Mengling Wong, Herman Gill
Publikováno v:
Nuclear Medicine and Biology. 51:10-17
Indoleamine and tryptophan 2,3-dioxygenases (IDO1 and TDO2) are pyrrolases catalyzing the oxidative cleavage of the 2,3-double bond of L-tryptophan in kynurenine pathway. In the tumor microenvironment, their increased activity prevents normal immune