Výsledky vyhledávání - "Simon P.S., Howarth"

Diencephalic syndrome in child with NF-1 and hypothalamic tumour

Autor: Pilotto, Chiara, Thomas, Adam, Simon P.S., Howarth, Didcock, Liz, Thomas, Shery, Walker, David A.

We describe a 20 month old boy with neuro-fibromatosis type 1 (NF-1) who presented with diencephalic syndrome due to a large hypothalamic tumour and developed massive necrosis after chemotherapy associated with severe encephalopathy.We report this ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::5452eca8f8e51ecdafae31b20ae6cf5d
https://nottingham-repository.worktribe.com/file/1035308/1/Diencephalic-syndrome-in-child-with-nf1-and-hypothalamic-tumour

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Effect of Low-and High-Dose Atorvastatin on Carotid Artery Distensibility Using Carotid Magnetic Resonance Imaging ^|^mdash;A Post-Hoc Sub Group Analysis of ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study

Autor: Jonathan H. Gillard, Tjun Y. Tang, Martin J. Graves, Umar Sadat, Simon P.S. Howarth, Valentina Taviani, Ammara Usman

Publikováno v: Journal of Atherosclerosis and Thrombosis. 20:46-56

Aim To assess the effect of low-(10 mg) or high-(80 mg) dose atorvastatin on carotid artery distensibility in patients with asymptomatic carotid artery disease using carotid magnetic resonance imaging. Methods Eighteen patients underwent initial 2-di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6deedba16b6f9c60762e55503e744f
https://doi.org/10.5551/jat.12633

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Iron Oxide Particles for Atheroma Imaging

Autor: Simon P.S. Howarth, Umar Sadat, Jonathan H. Gillard, Victoria E Young, Karin H. Müller, Zhi Y. Li, Tjun Y. Tang, Martin J. Graves, Stewart R. Walsh

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 29:1001-1008

The selection of patients for vascular interventions has been solely based on luminal stenosis and symptomatology. However, histological data from both the coronary and carotid vasculature suggest that other plaque features such as inflammation may b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d23bee65cc76c83c62fbcb37411abea
https://doi.org/10.1161/atvbaha.108.165514

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The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study

Autor: Andrew J. Patterson, Elizabeth A. Warburton, J.M. U-King-Im, Andrew Zalewski, Michael E. Gaunt, Zhi Y. Li, Martin J. Graves, Andy Brown, Jonathan R. Boyle, Jonathan H. Gillard, Peter J. Kirkpatrick, Kevin Varty, Sam R. Miller, Stewart R. Walsh, Paul D. Hayes, Simon P.S. Howarth, Tjun Y. Tang

Publikováno v: Journal of the American College of Cardiology. 53:2039-2050

Objectives The aim of this study was to evaluate the effects of low-dose (10 mg) and high-dose (80 mg) atorvastatin on carotid plaque inflammation as determined by ultrasmall superparamagnetic iron oxide (USPIO)-enhanced carotid magnetic resonance im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7d8b349bf19dcf1da86534304b1f49
https://doi.org/10.1016/j.jacc.2009.03.018

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Utility of USPIO-enhanced MR imaging to identify inflammation and the fibrous cap: A comparison of symptomatic and asymptomatic individuals

Autor: Sam R. Miller, Martin J. Graves, Zhiyong Li, Ruwan A. Weerakkody, Simon P.S. Howarth, Jean Marie U-King-Im, Tjun Y. Tang, Rikin A. Trivedi, Jonathan R. Boyle, Jonathan H. Gillard, Michael E. Gaunt

Publikováno v: European Journal of Radiology. 70:555-560

Inflammation is a risk factor the vulnerable atheromatous plaque. This can be detected in vivo on high-resolution magnetic resonance (MR) imaging using a contrast agent, Sinerem, an ultra-small super-paramagnetic iron oxide (USPIO). The aim of this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6dfd702ee3bf729dc4ec2226d0fcc4
https://doi.org/10.1016/j.ejrad.2008.01.047

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Temporal dependence of in vivo USPIO-enhanced MRI signal changes in human carotid atheromatous plaques

Autor: Jean Marie U-King-Im, Andrew J. Patterson, Zhiyong Li, Simon P.S. Howarth, Tjun Y. Tang, Victoria E Young, Jonathan R. Boyle, Umar Sadat, Sam R. Miller, Stewart R. Walsh, Martin J. Graves, Jonathan H. Gillard, Michael E. Gaunt

Publikováno v: Neuroradiology. 51:457-465

Ultrasmall superparamagnetic iron oxide (USPIO)-enhanced MRI has been shown to be a useful modality to image activated macrophages in vivo, which are principally responsible for plaque inflammation. This study determined the optimum imaging time-wind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983a5c48e0ffcf17f21bf03686c2286d
https://doi.org/10.1007/s00234-009-0523-x

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Correlation of Carotid Atheromatous Plaque Inflammation Using USPIO-Enhanced MR Imaging With Degree of Luminal Stenosis

Autor: Simon P.S. Howarth, Andrew J. Patterson, Tjun Y. Tang, Peter J. Kirkpatrick, Sam R. Miller, Martin J. Graves, Stewart R. Walsh, Jean-Marie U-King-Im, Elizabeth A. Warburton, Zhiyong Li, Kevin Varty, Michael E. Gaunt, Jonathan H. Gillard

Publikováno v: Stroke. 39:2144-2147

Background and Purpose— Inflammation is a recognized risk factor for the vulnerable atherosclerotic plaque. The study explores the relationship between the degree of Magnetic Resonance (MR)–defined inflammation using Ultra Small Super-Paramagneti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d82a664f3c46a9695982da982a85bb
https://doi.org/10.1161/strokeaha.107.504753

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Comparison of the inflammatory burden of truly asymptomatic carotid atheroma with atherosclerotic plaques contralateral to symptomatic carotid stenosis: an ultra small superparamagnetic iron oxide enhanced magnetic resonance study

Autor: Zhiyong Li, Sam R. Miller, Simon P.S. Howarth, Stewart R. Walsh, Peter J. Kirkpatrick, Tjun Y. Tang, Rikin A. Trivedi, Martin J. Graves, Jean Marie U-King-Im, Andy Brown, Michael E. Gaunt, Jonathan H. Gillard

Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 78:1337-1343

Background: Inflammation is a recognised risk factor for the vulnerable atherosclerotic plaque. The aim of this study was to explore whether there is a difference in the degree of magnetic resonance (MR) defined inflammation using ultra small superpa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bfec9b01dc4e21491e88a9154e8850
https://doi.org/10.1136/jnnp.2007.118901

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Internal Carotid Artery Stenosis: Accuracy of Subjective Visual Impression for Evaluation with Digital Subtraction Angiography and Contrast-enhanced MR Angiography

Autor: Simon P.S. Howarth, Jean Marie U-King-Im, Peter J. Kirkpatrick, Tjun Y. Tang, Martin J. Graves, Josephine Wat, Jonathan H. Gillard, N Higgins, Rikin A. Trivedi, Nagui M. Antoun, Justin J. Cross

Publikováno v: Radiology. 244:213-222

To prospectively determine, for both digital subtraction angiography (DSA) and contrast material-enhanced magnetic resonance (MR) angiography, the accuracy of subjective visual impression (SVI) in the evaluation of internal carotid artery (ICA) steno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869a86bdc565e6027f06de8dc07ca85d
https://doi.org/10.1148/radiol.2441060749

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